Operational configuration and temperature compensation methods are provided for bulk acoustic wave (BAW) resonator devices suitable for operating with liquids. Temperature compensation methods dispense with a need for temperature sensing, instead utilizing a relationship between (i) change in frequency of a BAW resonator at a phase with adequate sensitivity and (ii) change in frequency of a phase that is correlated to temperature. Operational configuration methods include determination of an initial phase response of a BAW resonator in which temperature coefficient of frequency is zero, followed by comparison of sensitivity to a level of detection threshold for a phenomenon of interest.

A method and apparatus for determining a gas influx into a wellbore. A work string defining an inner bore area and an annulus area, with a pair of inner bore sensors in the inner bore and a pair of annulus sensors in the annulus. A processor sets a gas influx alarm limit based on a steady-state value of an acoustic parameter measured by the pair of inner bore sensors in an absence of a gas influx and a steady-state value of the acoustic parameter measured by the annulus sensors in the absence of the gas influx. The processor determines a gas influx in the wellbore when a subsequent value of the acoustic parameter is outside of the alarm limit and performs an action at the work string to counteract the gas influx in the wellbore.

Systems and methods to measure states of charge of a battery may include an ultrasonic sensor and a control system. For example, the control system may instruct the ultrasonic sensor to emit ultrasonic waves toward a battery, and may instruct the ultrasonic sensor to receive echoes of the emitted ultrasonic waves reflected back from the battery. In addition, the control system may process data associated with the emitted waves and received echoes, including properties associated with the waves and echoes, such as a time of flight, frequency, amplitude, wavelength, phase, duration, or others. Based on the properties of the received echoes, and by comparison with expected properties, various physical, mechanical, chemical, and/or material characteristics of the battery may be determined, based on which a state of charge and/or a state of health of the battery may further be determined.

A method of detecting at least a blockage status in a porous member separating a measurement chamber of a device including a gas sensor positioned within the measurement chamber which is responsive to an analyte in an ambient environment to be sampled, includes emitting pressure waves from a pressure wave source which travel within the measurement chamber, measuring a first response via a first sensor responsive to pressure waves positioned at a first position within the measurement chamber, measuring a second response via a second sensor at a second position, different from the first position, and in fluid connection with the pressure wave source, determining the blockage status of the porous member based upon a functional relation of the first response and the second response.

A measurement method according to one embodiment, includes: preparing a detecting section on an upper surface of a measurement device with a reaction substance that can react specifically with a detection substance and a correction substance, wherein the detecting section measures signal values based on reactions of the reaction substance; supplying the detection substance onto the detecting section; supplying the correction substance onto the detecting section; measuring a first signal value of the signal values based on a specific reaction between the detection substance and the reaction substance; measuring a second signal value of the signal values based on a specific reaction between the correction substance and the reaction substance; and correcting the first signal value using the second signal value.

A bulk acoustic wave MEMS resonator device includes at least one functionalization (e.g., specific binding or non-specific binding) material arranged over a top side electrode, with at least one patterned enhanced surface area element arranged between a lower surface of the top side electrode and the functionalization material. The at least one patterned enhanced surface area element increases non-planarity of the at least one functionalization material, thereby providing a three-dimensional structure configured to increase sensor surface area and reduce analyte diffusion distance, and may also promote fluid mixing. Methods for biological and chemical sensing, and methods for forming MEMS resonator devices and fluidic devices are further disclosed.

Methods include treating a portion of a sample composition to be tested for presence of an analyte by depleting or blocking the target analyte. The treated composition may be used to equilibrate an acoustic wave sensor prior to exposing the sensor to the untreated sample composition for analysis. By using the treated sample composition, in which the analyte is depleted or blocked, to equilibrate the sensor, the sensor may be equilibrated with a composition having a similar viscosity and non-specific binding characteristics to the untreated sample composition, which should result in improved accuracy when analyzing the analyte in the untreated sample composition.

The invention comprises a device and method to estimate the elasticity of soft elastic solids from surface wave measurements. The method is non-destructive, reliable and repeatable. The final device is low-cost and portable. It is based in audio-frequency shear wave propagation in elastic soft solids. Within this frequency range, shear wavelength is centimeter sized. Thus, the experimental data is usually collected in the near-field of the source. Therefore, an inversion algorithm taking into account near-field effects was developed for use with the device. Example applications are shown in beef samples, tissue mimicking materials and in vivo skeletal muscle of healthy volunteers

A system for and method of antimicrobial susceptibility testing includes detecting a resonance peak of a sensor provided with live microbes on a surface thereof; applying a substance to the live microbes; detecting a resonance peak of said sensor after application of said substance; determining a width of a top of each of said resonance peaks before and after application of the substance from one of: (1) a phase angle versus frequency plot where the phase angle is the phase angle of the electrical impedance of said sensor. (2) a real part of a plot of an electrical impedance versus frequency of said sensor. (3) a plot of a magnitude of electrical impedance versus frequency of said sensor, and (4) a phase angle versus frequency plot where the phase angle is the phase angle between an output voltage and an input voltage of said sensor, and comparing the determined widths of tops of said resonance peaks or standard deviations of the frequency of said resonance peaks to determine antimicrobial susceptibility including the minimum inhibitory concentration (MIC).

A fluidic device includes at least one bulk acoustic wave (BAW) resonator structure with a functionalized active region, and at least one first (inlet) port defined through a cover structure arranged over a fluidic passage containing the active region. At least a portion of the at least one inlet port is registered with the active region, permitting fluid to be introduced in a direction orthogonal to a surface of the active region bearing functionalization material. Such arrangement promotes mixing proximate to a BAW resonator structure surface, thereby reducing analyte stratification, increasing analyte binding rate, and reducing measurement time.