Patent classifications
G01N2333/01
Biomimetic virus-based colorimetric sensors
The present invention provides, inter alia, a device comprising a colorimetric detection layer configured to undergo a color change upon interaction with a first analyte of interest. The detection layer comprises a first plurality of self-assembled fiber bundles. At least a fraction of the fiber bundles undergo a change from a first conformation to a second conformation upon interaction with the first analyte of interest, thereby undergoing a color change. The invention also provides a method for using the system to detect an analyte of interest.
POTENCY TEST FOR VACCINE FORMULATIONS
The invention relates to certain methods for the determination of an antigen content of a first antigen in a mixture comprising two or more antigens. The invention also relates to a potency test for an antigen in a combination vaccine. The method allows the determination of the antigen content in a mixture additionally comprising antibodies that are capable of binding with the antigen.
COMPOSITION FOR DETECTING POTATO VIRUS Y INCLUDING M13KO7 BACTERIOPHAGE AND KIT INCLUDING THE SAME
The present disclosure relates to a composition for detecting a potato virus Y including an M13KO7 bacteriophage and a kit including the same. Since the M13KO7 bacteriophage of the present disclosure may be easily produced using E. coli and is a large aggregate of proteins, the M13KO7 bacteriophage is more stable than antibodies even when exposed to external physical or chemical factors. Therefore, the composition of the present disclosure has an effect of diagnosing only the PVY specifically and accurately and may be usefully used in related industries.
Marker system, in particular for baculovirus-expressed subunit antigens
The present invention belongs to the field of compliance markers and marker vaccines which allow for the differentiation between infected and vaccinated individuals. In particular, it relates to a method of determining whether an individual has received an immunogenic composition comprising a recombinant protein produced by a baculovirus expression system in cultured insect cells.
ANTIBODY, COMPOSITE, DETECTION DEVICE AND METHOD USING SAME
The present invention is an antibody including an amino acid sequence, wherein the amino acid sequence includes, in an N- to C-direction, the following structural domains:
N-FR1-CDR1-FR2-CDR2-FR3-CDR3-FR4-C
wherein FR denotes a framework region amino acid sequence and CDR denotes a complementary determining region amino acid sequence; the CDR1 includes an amino acid sequence represented by SEQ ID NO: 1; the CDR2 includes an amino acid sequence represented by SEQ ID NO: 2; and the CDR3 includes an amino acid sequence represented by SEQ ID NO: 3.
The antibody is capable of binding to an intranuclear protein of an influenza virus.
BIOMIMETIC VIRUS-BASED COLORIMETRIC SENSORS
The present invention provides, inter alia, a device comprising a colorimetric detection layer configured to undergo a color change upon interaction with a first analyte of interest. The detection layer comprises a first plurality of self-assembled fiber bundles. At least a fraction of the fiber bundles undergo a change from a first conformation to a second conformation upon interaction with the first analyte of interest, thereby undergoing a color change. The invention also provides a method for using the system to detect an analyte of interest.
PRODUCTION METHOD AND DETECTION METHOD OF AFRICAN SWINE FEVER VIRUS
According to the present invention, immortalized cells derived from porcine kidney macrophages are found to have high infection susceptibility to various African swlne fever virus strains. As a result, using the cells, it is possible to proliferate the virus and furthermore produce and detect the virus.
AFRICAN SWINE FEVER DIVA IMMUNOASSAY
The invention relates to a diagnostic use of an African Swine Fever Vims CD2v protein, a method, a device, and a kit for the detection of the presence of ASFV antibodies in a test sample, in particular the use thereof in a DIVA immunoassay.
DISPLAY APPARATUS AND SENSING METHOD USING THE SAME
A display apparatus includes: a substrate including a sensor area and a display area, a plurality of biosensors disposed on the substrate and of which electrical resistance changes when exposed to a target material, and an organic insulating layer defining a plurality of openings therein, which expose the plurality of biosensors to the outside, where the display area includes a plurality of first through-portions, and a plurality of display portions spaced apart from each other by the plurality of first through-portions, and the sensor area includes a plurality of second through-portions, and a plurality of base portions spaced apart from each other by the plurality of second through-portions.
MARKER SYSTEM, IN PARTICULAR FOR BACULOVIRUS-EXPRESSED SUBUNIT ANTIGENS
The present invention belongs to the field of compliance markers and marker vaccines which allow for the differentiation between infected and vaccinated individuals. In particular, it relates to a method of determining whether an individual has received an immunogenic composition comprising a recombinant protein produced by a baculovirus expression system in cultured insect cells.