In one aspect, the disclosure relates to a compact membrane reactor for parahydrogen induced hyperpolarization, the reactor including an inner tube constructed of a semipermeable membrane, an outer tube surrounding the inner tube, and a means for controlling the magnetic field surrounding the outer tube. In some aspects, multiple compact membrane reactors can be arranged in parallel. In other aspects, the compact membrane reactor is equipped with a mechanism for magnetic field control. Also disclosed are fluid handling systems and sample preparation systems comprising the compact membrane reactors disclosed herein. The compact membrane reactor can be operated in a batch mode, a stopped-flow mode, or a continuous flow mode and can be configured to work with existing NMR spectrometers and MRI instruments.

A magnetic resonance (MR) system may include a MR device and a MR-compatible drive. The MR device may include a scanner with a basic magnet for generating a homogeneous basic magnetic field. The MR-compatible drive may include an electric motor with a stator. The stator of the electric motor may include a dominant component of the basic magnetic field of the basic magnet.

A device(100a(i), 100a(ii), 100a(iii), 100a(iv), 200 for cis-tracing polarization of .sup.12C isotope-based magnetic resource imaging contrast agents, comprising one or more diamond material structures(120(i), 120(ii), 120(iii), 120(iv), 210, 220) and one or more channels(105a(i), 105a (ii), 105a (iii), 105a (iv), 205) provided adjacent to the diamond material structures 120(i), 120(ii), 120(iii), 120(iv), 210, 220); the diamond material structures 120(i), 120(ii), 120(iii), 120(iv), 210, 220) provide a source of negatively charged nitrogen vacancy celles for polarization of a .sup.13C iso-type-based magnetic measure imaging contrast agesi disguised in one or more channels(105a (i), 105a (ii), 105a (iii), 105a (iv), 205) and cis diamond material structure(120(i), 120(ii), 120(iii), 120(iv), 210, 220) provides a light guide for light for excitation of nitrogen vacancy celles for polarization of .sup.13C isotope-based magnetic resource imaging contrast agent.

The present invention provides a multichannel radio frequency (RF) receive/transmit system (200) for use in an magnetic resonance (MR) imaging system (110), comprising a RF coil array (202) with multiple RF coil elements (204) for emission and reception of RF signals, whereby each RF coil element (204) is provided with tuning means (206), and a tuning/matching circuit (208) for comparing forward power provided to at least one of the RF coil elements (204) with reflected power at the respective RF coil element (204) of the at least one of the RF coil elements (204), and for tuning the at least one of the RF coil elements (204) based on a comparison of the forward power and the reflected power at least one of the RF coil elements (204). The present invention further provides a magnetic resonance (MR) imaging system (110) comprising the above multichannel RF receive/transmit system (200). Still further, the present invention further provides methods for performing magnetic resonance (MR) imaging using the above MR imaging system (110).

Reference data relating to a portion of a patient anatomy during patient motion can be acquired from a magnetic resonance imaging system (MRI) to develop a patient motion library. During a time of interest, tracking data is acquired that can be related to the reference data. Partial volumetric data is acquired during the time of interest and at approximately the same time as the acquisition of the tracking data. A volumetric image of patient anatomy that represents a particular motion state can be constructed from the acquired partial volumetric data and acquired tracking data.

Improved magnetic resonance imaging systems, methods and software are described including a low field strength main magnet, a gradient coil assembly, an RF coil system, and a control system configured for the acquisition and processing of magnetic resonance imaging data from a patient while utilizing a sparse sampling imaging technique.

An instrument, a magnetic resonance imaging scanner and a method for operating the magnetic resonance imaging scanner with the instrument in which the instrument is aligned with a patient. The medical instrument comprises a first projector for projecting a luminous pointer in a predetermined alignment relative to the medical instrument. The magnetic resonance imaging scanner comprises a positioning aid configured to mark a predetermined position on an inner wall of a patient tunnel in a manner that is visible to a user. In the method, a predetermined alignment of the first projector relative to the medical instrument or position of the positioning aid on the wall of the patient tunnel is ascertained in which the luminous pointer of the first projector coincides with the positioning aid when the medical instrument is aligned parallel to a trajectory through an entry point on the patient and a target point in the patient and the medical instrument is aligned such that the luminous pointer and the positioning aid coincide.

Techniques for correcting gradient non-linearity bias in mean diffusivity measurements by MRI systems are shown and include minimal number of spatial correction terms to achieve sufficient error control using three orthogonal diffusion weighted imaging (DWI) gradients. The correction is based on rotation of system gradient nonlinearity tensor into a DWI gradient frame where spatial bias of b-matrix is described by its Euclidian norm. The techniques obviate time consuming multi-direction acquisition and noise-sensitive mathematical diagonalization of a full diffusion tensor for medium of arbitrary anisotropy.

Techniques for correcting gradient non-linearity bias in mean diffusivity measurements by MRI systems are shown and include minimal number of spatial correction terms to achieve sufficient error control using three orthogonal diffusion weighted imaging (DWI) gradients. The correction is based on rotation of system gradient nonlinearity tensor into a DWI gradient frame where spatial bias of b-matrix is described by its Euclidian norm. The techniques obviate time consuming multi-direction acquisition and noise-sensitive mathematical diagonalization of a full diffusion tensor for medium of arbitrary anisotropy.

A method includes displaying a position of a distal end of a medical probe that is being navigated in an organ of a patient on a three-dimensional (3D) map of the organ. In response to an event, a plane of interest including the distal end is selected, a real-time Magnetic Resonance Imaging (MRI) slice of the organ is acquired at the selected plane, and the MRI slice is displayed overlaid on the 3D map.