The present disclosure provides NMR relaxation methods for characterizing iron carbohydrate drug products. The methods measure .sup.13C and .sup.1H nuclei relaxation parameters such as T1 and PWHH include performing 2D T1 NMR, 1D .sup.13C NMR and .sup.1H NMR to characterize certain physiochemical properties of iron sucrose drug products, for purposes of assessing bioequivalence between a tested iron sucrose product and a comparator product. The disclosure further provides a novel Fe(III)/Fe(II) reduction method using a new reducing agent Na.sub.2S.sub.2O.sub.5 and an .sup.1H NMR method to monitor the Fe(III)/Fe(II) reduction process.

According to some aspects, a method of suppressing noise in an environment of a magnetic resonance imaging system is provided. The method comprising estimating a transfer function based on multiple calibration measurements obtained from the environment by at least one primary coil and at least one auxiliary sensor, respectively, estimating noise present in a magnetic resonance signal received by the at least one primary coil based at least in part on the transfer function, and suppressing noise in the magnetic resonance signal using the noise estimate.

A radio-frequency (RF) coil for use in a low-field magnetic resonance imaging system and methods of making the same are provided. The RF coil may include a conductor arranged on a substrate in an arrangement such that symmetry in the arrangement cancels at least a portion of a common mode voltage when a current is passed through the conductor. The RF coil may be included in a magnetic resonance imaging (MRI) system for imaging a patient having at least one B.sub.0 magnet for generating a B.sub.0 magnetic field.

A magnetic resonance imaging (MRI) system and method for acquiring magnetic resonance (MR) images using a pulse sequence implementing driven equilibrium and quadratic phase cycling techniques is provided. The method includes, during a pulse repetition period of a pulse sequence and using a quadratic phase cycling scheme, applying a first RF pulse to deflect a net magnetization vector associated with the subject from a longitudinal plane into a transverse plane; after applying the first RF pulse, applying a first sequence of RF pulses each of which flips the net magnetization vector by approximately 180 degrees within the transverse plane; and after applying the first sequence of RF pulses, applying a second RF pulse to deflect the net magnetization vector from the transverse plane to the longitudinal plane.

A system and method are provided for producing at least one of an image or a map of a subject includes controlling a magnetic resonance imaging (MRI) system to perform a pulse sequence that includes a phase increment of an RF pulse selected to induce a phase difference between two echoes at different echo times (TE). The method also includes controlling the MRI system to acquire MR data corresponding to at least the two echoes at different TEs, deriving a static magnetic field (B0) map of the MRI system using the MR data corresponding to the two echoes, and using the B0 map and MR data from at least one of the two echoes, generate a map of T2 of the subject.

A subject S to which .sup.17O gas has been administered is placed within a fixed uniform static magnetic field of an NMR apparatus 1. The subject is irradiated, through proton coupling, with an excitation pulse produced using a pulse sequence having a short cycle time of 20.4 msec or less, preferably 10.4 msec or less, and more preferably 5.6 msec or less. An NMR signal generated due to .sup.17O nuclei of .sup.17O water produced within the subject by oxygen metabolism of the .sup.17O gas being excited by irradiation with the excitation pulse is detected with high sensitivity and is processed in accordance with a prescribed imaging sequence in which an MRS sequence is used.

Object specific in-homogeneities in an MRI system are corrected. Prescan information available at the MR imaging system is determined. The prescan information includes at least object specific information of an object located in the MR imaging system from which an MR image is to be generated. The prescan information does not include a B1 map of the MRI system with the object being present in the MR imaging system. The prescan information is applied to a trained machine learning module provided at the MRI system. The trained machine learning module determines and generates shimming information as output. The shimming information is applied to a shimming module of the MR imaging system, wherein the shimming module uses the shimming information to generate a corrected magnetic field B0.

A method of using the relaxation rate (R.sub.1 and/or R.sub.2) of solvent NMR signal to noninvasively assess whether viral capsids in a capsid preparation are full or empty, and the percentage of full capsids if the vial contains a mixture of full and empty capsids. The method can simply, rapidly, and non-invasively prove the safety and potency of the capsid preparation and thus whether the capsid preparation can be approved for clinical use, without requiring any sample preparation or reagent addition.

In a Method and a device for magnetic resonance imaging of a subject using a spoiled gradient echo sequence, a B.sub.0 magnetic field strength of at most 1.5 T is used during the sequence. As part of the sequence a slice select gradient acting as a spoil gradient is played out. Substantially simultaneously with the slice select gradient a predetermined RF pulse is played out in the sequence, wherein a time-bandwidth product of the RF pulse is set so that a majority of the energy of the RF pulse is transmitted in its central main lobe.

Downhole properties of a geological formation may be determined using nuclear magnetic resonance (NMR) measurements obtained by a moving tool. To do so, an interpretation of the NMR data obtained by the moving data may take into account a moving model, characterization, or calibration of the downhole NMR tool. Additionally or alternatively, a partial interpretation mask may exclude interpretation of certain areas of data (e.g., T1-T2 data points or diffusion-T2 data points) that are expected to be less likely to describe downhole materials of interest.