The present disclosure relates to a contact lens type dosimeter for measuring a dose distribution of a crystalline lens during radiation therapy, and a method of manufacturing the same. The ocular dosimeter has a contact lens shape and is configured to be worn on an eyeball, which comprises a basic material containing hydrophilic polyurethane, and a radiochromic dye. When the ocular dosimeter is worn on the eyeball, the dosimeter is configured to measure a radiation dose irradiated to a crystalline lens through a variation in color of the ocular dosimeter.

The present disclosure relates to a contact lens type dosimeter for measuring a dose distribution of a crystalline lens during radiation therapy, and a method of manufacturing the same. The ocular dosimeter has a contact lens shape and is configured to be worn on an eyeball, which comprises a basic material containing hydrophilic polyurethane, and a radiochromic dye. When the ocular dosimeter is worn on the eyeball, the dosimeter is configured to measure a radiation dose irradiated to a crystalline lens through a variation in color of the ocular dosimeter.

Real-time X-ray dosimetry sensing in intraoperative radiation therapy (IORT). According to one aspect, a treatment head comprises at least one X-ray component configured to facilitate generation of therapeutic radiation in the X-ray wavelength range. A resilient balloon is disposed over the treatment head and configured for receiving therein a fluid to facilitate X-ray treatment of a tumor cavity. A plurality of X-ray sensing elements is disposed at a plurality of locations distributed on the interior or exterior of the resilient balloon and configured for sensing X-ray radiation emanating from the treatment head. A control system is provided that is responsive to data received from the X-ray sensing elements to determine a magnitude of X-ray radiation detected at each of the X-ray sensing elements.

Real-time X-ray dosimetry sensing in intraoperative radiation therapy (IORT). According to one aspect, a treatment head comprises at least one X-ray component configured to facilitate generation of therapeutic radiation in the X-ray wavelength range. A resilient balloon is disposed over the treatment head and configured for receiving therein a fluid to facilitate X-ray treatment of a tumor cavity. A plurality of X-ray sensing elements is disposed at a plurality of locations distributed on the interior or exterior of the resilient balloon and configured for sensing X-ray radiation emanating from the treatment head. A control system is provided that is responsive to data received from the X-ray sensing elements to determine a magnitude of X-ray radiation detected at each of the X-ray sensing elements.

A radiation monitor apparatus and method based on wavelength-dependent optical absorption in fused silica optical fibers. The radiation monitor uses the radiation induced optical changes in fused silica optical fibers as a way to quantify and differentiate the large doses of radiation from high energy photons and neutrons as well as providing a method to extend the sensitivity over a large dynamic range of doses from 103 to beyond 106 rads. The radiation monitor enables dynamic monitoring of highly ionizing radiation environments. The radiation monitor reduces sensitivity saturation at high dose levels, provides increased sensitivity over a large dynamic range of doses, and enables differentiation between high energy photon and neutron contributions or poor signal to noise.

A radiation monitor apparatus and method based on wavelength-dependent optical absorption in fused silica optical fibers. The radiation monitor uses the radiation induced optical changes in fused silica optical fibers as a way to quantify and differentiate the large doses of radiation from high energy photons and neutrons as well as providing a method to extend the sensitivity over a large dynamic range of doses from 103 to beyond 106 rads. The radiation monitor enables dynamic monitoring of highly ionizing radiation environments. The radiation monitor reduces sensitivity saturation at high dose levels, provides increased sensitivity over a large dynamic range of doses, and enables differentiation between high energy photon and neutron contributions or poor signal to noise.

An implantable dosimeter uses salt crystals such as NaCl or KCl, or other materials that vary in color as a function of incident, ionizing radiation. The color change of the salts may occur through the creation of F-centers, where electrons become trapped in crystal defects (e.g., halide vacancies) and absorb light at certain wavelengths. Vacancies in the salt crystals absorb photons at precise wavelengths. Thus, the change in color can be correlated to the integrated dose in an implantation site. The salt crystals may be optically coupled to optical fibers or the like for remote measurement of color using, e.g., a spectrometer and a computer system. In this manner, the dosage of ionizing radiation can be measured in vivo with a fault tolerant, passively integrating dosimeter.

An implantable dosimeter uses salt crystals such as NaCl or KCl, or other materials that vary in color as a function of incident, ionizing radiation. The color change of the salts may occur through the creation of F-centers, where electrons become trapped in crystal defects (e.g., halide vacancies) and absorb light at certain wavelengths. Vacancies in the salt crystals absorb photons at precise wavelengths. Thus, the change in color can be correlated to the integrated dose in an implantation site. The salt crystals may be optically coupled to optical fibers or the like for remote measurement of color using, e.g., a spectrometer and a computer system. In this manner, the dosage of ionizing radiation can be measured in vivo with a fault tolerant, passively integrating dosimeter.

The present invention relates to a head and neck simulation phantom device for simulating the head and neck of a body, the phantom device including: a flat type first plate having a first insertion groove formed on one surface thereof; a flat type second plate disposed to come into contact with the other surface of the first plate and having a second insertion groove formed on the contacted surface with the other surface of the first plate in such a manner as to correspond to the first insertion groove; and a plurality of teeth simulants inserted into the first insertion groove and the second insertion groove and for simulating the teeth of the body.

The use of radiochromic film for measuring the spatial distribution of the Linear Energy Transfer (LET) deposited by protons is described. The film is dosed with a proton beam and scanned to record grey-levels of the film. The grey-levels are converted to a measured dose using calibration films and the measured dose is compared to a calculated dose to generate a scaled-normalized difference (SND) between the calculated dose and the measured dose. An improved method and apparatus for treating an abnormal condition using radiation therapy in a patient in need thereof based on a measured LET is also provided.