To provide a technique for evaluating a nuclear medicine brain image, the technique being hardly affected by the difference in the setting of reference regions. An embodiment of the present invention generally includes: setting a reference region on a region corresponding to the scalp in the nuclear medicine brain image; calculating information on a pixel value in the set reference region; and normalizing, using the information, a pixel value of each pixel included in the nuclear medicine brain image or a value obtained from the pixel value, and outputting the normalized value.

A non-transitory computer-readable medium stores instructions readable and executable by a workstation (18) including at least one electronic processor (20) to perform an image reconstruction method (100) to reconstruct list mode data acquired over a frame acquisition time using a plurality of radiation detectors (17) in which the events of the list mode data is timestamped. The method includes: for the sub-frame bins of a plurality of sub-frame bins into which the frame acquisition time is divided, determining a sub-frame singles rates map for the plurality of radiation detectors from the list mode data whose time stamps reside in the sub-frame bin; determining a singles rate for the singles events of the list mode data using the sub-frame singles rates maps wherein the singles rates for the singles events are determined at a temporal resolution that is finer than the frame acquisition time; determining correction factors for the list mode data using the determined singles rates for the singles events of the list mode data; and reconstructing the list mode data of the frame acquisition time using the determined correction factors to generate a reconstructed image for the frame acquisition time.

An imaging system (36) includes a Positron Emission Tomography (PET) scanner (38) and one or more processors (52). The Positron Emission Tomography (PET) scanner (38) which generates event data including true coincident events and scatter events, the event data includes each end point of a line of response (LOR) and an energy of each end point. The one or more processors (52) are programmed to generate (72) a plurality of activity map and attenuation map pairs based on the true coincident events, and select (76) an activity map and an attenuation map from the plurality of activity and attenuation map pairs based on the scattered events.

An imaging system (36) includes a Positron Emission Tomography (PET) scanner (38) and one or more processors (52). The Positron Emission Tomography (PET) scanner (38) which generates event data including true coincident events and scatter events, the event data includes each end point of a line of response (LOR) and an energy of each end point. The one or more processors (52) are programmed to generate (72) a plurality of activity map and attenuation map pairs based on the true coincident events, and select (76) an activity map and an attenuation map from the plurality of activity and attenuation map pairs based on the scattered events.

Provided are a radiation detector, a radiographic imaging apparatus, and a manufacturing method that include a TFT substrate in which a plurality of pixels that accumulate electric charges generated depending on light converted from radiation are formed in a pixel region of a first surface of a flexible base material and a terminal region of the first surface is provided with a terminal for electrically connecting a flexible cable; a conversion layer that is provided outside the terminal region on the first surface of the base material to convert the radiation into light; a first reinforcing substrate that is provided on a surface of the conversion layer opposite to a surface on a TFT substrate side and has a higher stiffness than the base material; and a second reinforcing substrate that is provided on a second surface of the base material opposite to the first surface to cover a surface larger than the first reinforcing substrate, and that are capable of suppressing that a defect occurs in the substrate and have an excellent peeling property in a reworking process.

A method is provided for updating a uniformity map of a detector. The detector defines a detector surface area. The method includes positioning a flood on a sub-portion of the detector surface area of the detector. The flood defines a flood area that is smaller than the detector surface area. Also, the method includes collecting counts from the flood for the sub-portion of the detector surface area. Further, the method includes updating an adjustment portion of the uniformity map using the counts collected for the sub-portion of the detector surface area, wherein the adjustment portion corresponds to at least a part of the sub-portion of the detector surface area.

A method is provided for updating a uniformity map of a detector. The detector defines a detector surface area. The method includes positioning a flood on a sub-portion of the detector surface area of the detector. The flood defines a flood area that is smaller than the detector surface area. Also, the method includes collecting counts from the flood for the sub-portion of the detector surface area. Further, the method includes updating an adjustment portion of the uniformity map using the counts collected for the sub-portion of the detector surface area, wherein the adjustment portion corresponds to at least a part of the sub-portion of the detector surface area.

An apparatus is described herein. The apparatus comprises a first modality unit and a second modality unit. The first modality unit is located within a gantry. The second modality unit within the gantry is moveable along an examination axis to be concentric about with the first modality unit such that a field of view of the first modality unit and a field of view of the second modality unit are centered about a single point of interest.

A system and method for measuring a dose of ionizing radiation received by a pre-determined part of the body during radiotherapy or interventional procedures. The system comprises: a) a light guide, which under the influence of ionizing radiation undergoes measurable and quantifiable physical changes; b) a detector system which allows the recording and quantification of the signal emitted by the light guide; and c) a control unit which is adapted for calculating a dose of ionizing radiation previously or simultaneously received by the light guide on basis of said response signal. The light guide is coated over at least part of its length with a coating comprising a first component acting as a place dependent spectral filter and a second component including at least one luminescent material, dispersed in a transparent matrix. When exposed to radiation, the luminescent component will emit light with a spectrum depending on the chosen material.

A system and method for measuring a dose of ionizing radiation received by a pre-determined part of the body during radiotherapy or interventional procedures. The system comprises: a) a light guide, which under the influence of ionizing radiation undergoes measurable and quantifiable physical changes; b) a detector system which allows the recording and quantification of the signal emitted by the light guide; and c) a control unit which is adapted for calculating a dose of ionizing radiation previously or simultaneously received by the light guide on basis of said response signal. The light guide is coated over at least part of its length with a coating comprising a first component acting as a place dependent spectral filter and a second component including at least one luminescent material, dispersed in a transparent matrix. When exposed to radiation, the luminescent component will emit light with a spectrum depending on the chosen material.