An optical lens for use in a media feed device, having a first lens surface and a second lens surface, wherein the first lens is provided to be facing an object to be observed and the second lens surface is provided to be facing away from the object to be observed. At least one channel opening onto the first lens surface is present, wherein the at least one channel runs through the optical lens and at least one section of a media line is formed in the at least one, channel or, if a plurality of channels are formed, at least one of the plurality of channels opens up outside a highest point in alignment with a line that is vertical with respect to the first lens surface and to the surface of the earth.

In a case where a microscope apparatus main body scans the bottom surface of the cultivation container by synchronously controlling a piezoelectric element and an actuator serving as optical axis-directional transport devices having different properties from each other, an objective lens of the imaging optical system is transported to a focus position in the optical axis direction.

A three-dimensional viewing includes a pair of digital image sensors in communication with a pair of digital displays and controlled by a pair of processors to render three-dimensional images of samples on the displays.

An optical imaging system for imaging a target during a medical procedure, the imaging system involving an optical assembly having moveable zoom optics and moveable focus optics, a zoom actuator and a focus actuator for positioning the zoom and focus optics, respectively, a controller for controlling the zoom and focus actuators independently in response to received control input, a camera for capturing an image of the target from the optical assembly, the system capable of performing autofocus during a medical procedure.

A medical observation control device and system include a memory that stores a parameter for a first imaging condition of an imager at a first time of capturing a first medical image and circuitry configured to correct for brightness differences between the first medical image captured at the first time and a second medical image captured at a second time. The circuitry is configured to restore the parameter for the first imaging condition as a second imaging condition for capturing the second medical image, control the imager so as to capture an image of an observation object under the second imaging condition as the second medical image, compare the first medical image with the second medical image, and correct brightness of at least one of brightness of the first medical image and brightness of the second medical image based on a comparison result.

A mobile phone-based dark field microscope (MDFM) apparatus suitable for quantifying nanoparticle signals is provided. The MDFM apparatus includes an electrically operated light source, a dark-field condenser, a slide housing configured to receive an analytical slide, and an adapter housing configured to receive an objective lens and receive a portable electronic communication device. The slide housing positions the analytical slide between the objective lens and the dark-field condenser. The adapter housing registers the objective lens with a camera lens of the portable electronic communication device. A method for performing a biological quantitative study using the dark-field microscope apparatus is further provided.

A method for operating a microscopy system and to a microscopy system are provided. A pivot point is defined, wherein the microscopy system is operated such that a microscope of the microscopy system moves at a constant distance around the pivot point, wherein a reference surface is determined, wherein an intersection of an optical axis of the microscope and the reference surface is determined as the pivot point, wherein the pose of the reference surface is defined in a focal position-independent reference coordinate system and the pivot point is determined as the intersection of the optical axis with the thus defined reference surface in the reference coordinate system.

The present invention provides microscopes and optical devices able to provide improved spherical aberration correction through the combined use a first optical system which comprises a common moveable or deformable rear lens system which forms part of the microscope objective in conjunction with a semi-objective lens system, and a second optical system which comprises a telescopic focusing system. Deforming, moving or repositioning one or more lenses of the common moveable or deformable rear lens system in the first optical system is able to act primarily on the anterior Gauss particulars (or the front conjugate) of the objective, while the telescopic focusing system of the second optical system is able to act on both the anterior and posterior Gauss particulars (or the front and rear conjugates). Adjustment of both optical systems in combination with one another allows for the formation of an improved image with enhanced spherical aberration correction.

A three-dimensional viewing includes a pair of digital image sensors in communication with a pair of digital displays and controlled by a pair of processors to render three-dimensional images of samples on the displays.

A surgical microscope system includes a surgical microscope. In the surgical microscope, variable power optical systems are arranged horizontally to fold optical paths, thereby reducing a vertical size between eyepieces of the surgical microscope and a lower end of the same and expanding a working space under the surgical microscope. A camera is attached to an upper part of the surgical microscope to free a side face of the surgical microscope so that an accessory such as a fluorescent camera is attached to the side face.