G02B21/241

Microscope apparatus and objective lens unit
11249296 · 2022-02-15 · ·

A microscope apparatus includes a base, a support disposed upright on the base, and an objective lens unit supported by the support and including an objective lens holder that holds an objective lens. The objective lens unit includes a drive source that moves the objective lens holder up and down and a driver that transmits a drive force of the drive source to the objective lens holder.

KIT FOR MICROSCOPIC OBSERVATION ASSOCIABLE WITH AN IMAGE ACQUISITION DEVICE
20210396983 · 2021-12-23 ·

A kit (10) includes a light source (12) and an optical system (14) equipped with a lens assembly (25) defining a magnification optical axis (X-X). A frame (16) is crossable by the light generated by the light source (12). The frame (16) is configured for supporting a sample holder (H), a portable electronic apparatus (S) equipped with an image acquisition device (C), and the optical system (14), which are interposable between the sample holder (H) and the image acquisition device (C). The optical system (14) is configured for being movable in a guided manner on the frame (16), to allow aligning the optical axis (X-X) with the image acquisition device (C). A carrying body (18) is configured for receiving in abutment the frame (16) and housing the light source (12) directing light towards the optical system (14) through the frame (16).

MICROSCOPE SYSTEM FOR IMAGING A SAMPLE REGION AND CORRESPONDING METHOD
20210396984 · 2021-12-23 ·

A microscope system for imaging at least one region of a sample includes: an image generating unit for microscopic imaging of a section of a sample region to be imaged acquired in an observation beam path; a movement unit for moving the section to be imaged into the observation beam path of the image generating unit; a graphic user interface displayed on a display for establishing a movement range corresponding to the sample region to be imaged by way of at least one user input, the graphic user interface displaying a coordinate system and, after input of at least one point in the displayed coordinate system, the movement range is established as a defined movement volume; and a control unit for activating the movement unit as a function of the defined movement volume so as to approach a set of sections corresponding to the defined movement volume in succession.

VIBRATION DRIVING DEVICE, APPARATUS EQUIPPED WITH VIBRATION DRIVING DEVICE, CONTROL DEVICE AND CONTROL METHOD FOR VIBRATION ACTUATOR
20210399654 · 2021-12-23 ·

A vibration driving device that improves controllability in low speed driving. The vibration driving device includes a vibration actuator that includes a vibrator that has an elastic member and an electro-mechanical energy conversion element, a contact member that contacts the vibrator, and a control device that controls drive of the vibration actuator. The control device includes a speed detection unit that detects speed information showing relative speed of the vibrator and the contact member, and an adjustment unit that decreases amplitude of vibration excited in the vibrator in a case where the speed detection unit detects that a state where the vibration actuator does not operate approximately and a state where the vibration actuator operates at a speed faster than a target driving speed occur alternately after starting to drive the vibration actuator.

COMPRESSED ACQUISITION OF MICROSCOPIC IMAGES

A microscope for computational imaging may include an illumination source configured to illuminate a sample with a plurality of wavelengths, an image sensor, an objective lens to image the sample onto the image sensor, and a processor operatively coupled to the illumination assembly and the image sensor. The processor may be configured to acquire a first image dataset from the sample illuminated using a first set of illumination conditions at a first wavelength. The processor may also be configured to acquire a second image dataset from the sample illuminated using a second set of illumination conditions having a second number of illumination conditions at a second wavelength. The second set of illumination conditions comprises fewer illumination conditions than the first set in order to decrease acquisition time. The processor may be configured to combine the first and second image datasets into a computationally reconstructed image of the sample.

DIGITAL MICROSCOPE AND MICROSCOPIC SET

The invention concerns a digital microscope for capturing images of a sample with an extended depth of field. The microscope comprises a stand (01) with an opening (16) for receiving an optical unit (07). The microscope further comprises an optical unit (07) with an objective (08), an image sensor, and a microelectromechanical optical system on an optical path from the objective (08) to the image sensor. The microelectromechanical optical system is configured for extending a depth of field at the optical path. According to the invention, the imaging unit (07) comprises a mounting unit (13) comprising a first portion (14) for removable mounting the mounting unit (13) into the opening (16) of the stand (01), a second portion (18) for removable mounting an illumination unit (17) onto the mounting unit (13), and a third portion (21) for removable mounting an additional lens (19) onto the mounting unit (13) into an optical axis (22) of the objective (08). Furthermore, the invention concerns a microscopic set.

Imaging system and method using a projected reference to guide adjustment of a correction optic
11194146 · 2021-12-07 · ·

System and method using a projected reference to guide adjustment of a correction optic. In an exemplary method, a reference may be projected onto an imaging detector by propagation of light generally along an optical axis that extends from the reference, through an objective, to a surface of a sample holder, and from the surface, back through the objective, to the imaging detector. The light may propagate through an off-axis aperture located upstream of the imaging detector and spaced from the optical axis. A plurality of images of the reference may be captured using the imaging detector, and with a correction optic at two or more different settings. A setting for the correction optic may be selected based on the plurality of images, and a sample may be imaged while the correction optic has the selected setting.

OPTICAL SYSTEM, METHOD FOR CALIBRATING OPTICAL SYSTEM, AND SEQUENCING SYSTEM
20210373314 · 2021-12-02 ·

An optical system including a first light source, a first lens, and a light splitting module, wherein the light splitting module has a first splitter, a second lens, a first camera and a second camera, the first lens is configured for receiving a first light beam from the first light source and collimating the first light beam onto a sample, and for receiving and collimating a light beam from the sample, the second lens is configured for focusing the collimated light beam from the first lens to the first camera and the second camera, the first splitter is configured for splitting the focused light beam from the second lens into a second light beam and a third light beam, the first camera is configured for receiving the second light beam, and the second camera is configured for receiving the third light beam.

Microsection sample stabilizer

A microsection sample stabilizer for aligning and stabilizing a microsection sample for microscopic inspection includes a frame including a base and at least one leveling portion supported by the base. The at least one leveling portion can define a viewing window for a microscope. The microsection sample stabilizer includes an interior region within the frame, and at least one compliant device operable within the interior region of the frame and operable to be supported by the base. The compliant device receives and supports the microsection sample, and biases the microsection sample against the at least one leveling portion of the frame to stabilize the microsection sample, such that an examination plane surface of the microsection sample is aligned and viewable through the viewing window by the microscope.

NON-CONTACT WIDE ANGLE RETINA VIEWING SYSTEM
20220175241 · 2022-06-09 · ·

A retina viewing system and method of using the same includes an ophthalmic microscope, a disposable lens attachment, and an electronic control unit (ECU). The microscope has an optical head and a set of internal focusing lenses, the latter providing the microscope with a variable working distance or focal length. The disposable lens attachment includes a resilient body with a proximal end connected to the optical head and a distal end connected to a high-power/high-diopter distal lens. The ECU executes instructions for viewing a retina or other intraocular anatomy of a patient eye. Execution of the instructions causes the ECU to automatically adjust the variable working distance or focal length of the microscope when viewing an image of the retina through the distal lens.