A material, article, system and method include a probe composition that includes a hydrophobic portion, a hydrophilic portion, an analyte-binding portion and a fluorophore portion. The analyte-binding portion is configured to bind to an analyte in an aqueous solution. The fluorophore portion is configured to change an optical property of fluorescent light emitted in response to incident excitation light when the probe composition changes between a first state in which the analyte is not bound to the analyte-binding portion and a second state in which the analyte binds to the analyte-binding portion. A material includes the probe composition and a silicone hydrogel substrate having a hydrogel network that allows flow of aqueous solution through the solution and a silicone network that occupies interstices of the hydrogel network. A contact lens having the material enables remote detection of glucose concentration in tear fluid of a subject.

A material, article, system and method include a probe composition that includes a hydrophobic portion, a hydrophilic portion, an analyte-binding portion and a fluorophore portion. The analyte-binding portion is configured to bind to an analyte in an aqueous solution. The fluorophore portion is configured to change an optical property of fluorescent light emitted in response to incident excitation light when the probe composition changes between a first state in which the analyte is not bound to the analyte-binding portion and a second state in which the analyte binds to the analyte-binding portion. A material includes the probe composition and a silicone hydrogel substrate having a hydrogel network that allows flow of aqueous solution through the solution and a silicone network that occupies interstices of the hydrogel network. A contact lens having the material enables remote detection of glucose concentration in tear fluid of a subject.

A contact lens, which can be any of a conventional rigid contact lens, an orthokeratology lens, a scleral lens or a soft contact lens, which has one or more peripheral annular zones adjacent to and radially outward from a central optical zone of the contact lens. The peripheral annular zones include an alignment zone for orientation control, upright control or peripheral alignment to improve the molding effect of an orthokeratology lens, a comfort or vision quality of a regular RGP, scleral contact lens or soft contact lens. The sagittal height of the lens in the alignment zone along a sub-axis differs from the sagittal height of the lens along at least one other sub-axis.

A method comprises: disposing a measurement contact lens upon an eye of a user; capturing at least one image of the eye and the measurement contact lens with an image sensor while the measurement contact lens is on the eye of the user and the eye is illuminated; processing the at least one image to obtain a centration of the measurement contact lens on the cornea of the eye; processing the at least one image to obtain an angular orientation of the measurement contact lens on the cornea of the eye; and determining, based on the centration and angular orientation of the measurement contact lens on the cornea of the eye, at least one parameter of a first contact lens to be worn on the eye with display eyewear or a second contact lens to be worn on the eye without the display eyewear.

A contact lens (201) includes an optic zone (202) that is centred on an optical axis (219), and a peripheral zone (204) surrounds the optic zone (202). A cross-sectional slice through the optic zone (202) along a meridian comprises a series of successive arcs (203a-203h) having a radial curvature power profile. The radial curvature power profile increases monotonically with radial distance from the optical axis (219). Light rays from a distant point source passing through the midpoint of each arc converge toward a point (215) on the first optical axis (203a-203h). For each arc (203a-203h), light rays from a distant point source pass through that arc (203a-203h) and converge towards a point (216) that is spaced away from the optical axis by a first distance. Methods of designing and manufacturing such contact lenses (201) are also described.

A contact lens (201) includes an optic zone (202) that is centred on an optical axis (219), and a peripheral zone (204) surrounds the optic zone (202). A cross-sectional slice through the optic zone (202) along a meridian comprises a series of successive arcs (203a-203h) having a radial curvature power profile. The radial curvature power profile increases monotonically with radial distance from the optical axis (219). Light rays from a distant point source passing through the midpoint of each arc converge toward a point (215) on the first optical axis (203a-203h). For each arc (203a-203h), light rays from a distant point source pass through that arc (203a-203h) and converge towards a point (216) that is spaced away from the optical axis by a first distance. Methods of designing and manufacturing such contact lenses (201) are also described.

The present invention relates to ophthalmic and non-ophthalmic systems with blue light filtering and Yellowness Index ranges. UV and IR filtering are also included. Industrial applications are also outlined in the invention.

The present invention relates to ophthalmic and non-ophthalmic systems with blue light filtering and Yellowness Index ranges. UV and IR filtering are also included. Industrial applications are also outlined in the invention.

The stabilized contact lens methods and apparatus disclosed herein provide improved stabilization of a contact lens placed on a cornea of an eye. The contact lens comprises stabilization zones that allow the lens to repeatedly and consistently orient on the cornea such that a sensing zone located on the lower portion of the lens is located inferiorly to engage the lower eyelid. The stabilized contact lens can provide a lower pressure sensing zone with decreased thickness for pressure or other sensing related to the lower eyelid. The decreased thickness has the advantage of improving coupling between forces from an eyelid and a lower chamber of a fluidic module. The improved coupling allows increased amounts of fluid to move between the lower chamber and an upper optical chamber coupled to the lower chamber, such that the upper chamber can increase curvature and optical power in response to pressures of the eyelid.

A lens for refractive tear shaping, including a curved lens body defining an anterior partial thickness cavity indented into its anterior surface. The anterior partial thickness cavity has an anterior facing tear shaping surface structured to form a tear lens within the anterior partial thickness cavity. The anterior partial thickness cavity is structured to define a tear lens within the anterior partial thickness cavity by interaction between a tear film of the eye and the anterior facing base tear shaping surface. The posterior curvature of the tear lens is dependent on the shape of the anterior facing base tear shaping surface.