An ophthalmic lens that includes a lens material having two opposing curved surfaces, the curved surfaces defining a lens axis; and a light scattering region surrounding a clear aperture. The clear aperture and the light scattering region are substantially centered on the lens axis, and the light scattering region has a plurality of spaced apart scattering centers (e.g., on a lens surface and/or embedded in the lens material) sized and shaped to scatter incident light, the scattering centers being arranged in a pattern that includes a random variation in spacing between adjacent dots and/or a random variation in dot size.

Pinhole glasses include an eyeglass frame, a processed lens which is fixed to the eyeglass frame and made of an opaque material, and a plurality of pinholes formed at the processed lens. In order to form the pinholes, based on eyes of a user, a plurality of longitudinal patterns are formed on the inner side thereof at regular intervals and a plurality of transverse patterns are formed on the outer side thereof at regular intervals to intersect the longitudinal patterns, thereby forming a plurality of square-shaped pinholes.

A mask configured to be implanted in a cornea of a patient to increase the depth of focus of the patient includes an anterior surface, a posterior surface, and a plurality of holes. The anterior surface is configured to reside adjacent a first corneal layer. The posterior surface is configured to reside adjacent a second corneal layer. The plurality of holes extends at least partially between the anterior surface and the posterior surface. The holes of the plurality of holes are configured to substantially eliminate visible diffraction patterns.

One embodiment of an aspect of the present invention is a pair of eyeglasses having at least one lens with a plurality of holes for natural improvement of eyesight or vision. The holes may be of different sizes and shapes and may be randomly positioned throughout the lens, and the lens may be painted upon. Another embodiment of this aspect is a pair of eyeglasses that has at least one lens with a plurality of holes and that also has a patch. Another aspect of the present invention is a method for natural improvement of eyesight or vision through the use of the eyeglasses of the present invention.

A method of compensating for a refractive error, including manipulating eyelashes to project into a line of sight of an eye at least when an eyelid from which the eyelashes extend is partially closed or when the eye is moved relative to the eyelid. The method may further include manipulating at least one of spacing, orientation, direction, contour or shape of the eyelashes to create an optical effect that improves visual acuity when the eyelashes project into the line of sight and training an individual whose eyelashes are manipulated to position the eyelid from which the eyelashes extend, the eye or both the eyelid and the eye from which the eyelashes extend to achieve relative positioning of the eye and the eyelid to obtain the optical effect that improves visual acuity when desired.

A mask is provided that is configured to increase the depth of focus of a patient. The mask can include an aperture configured to transmit along an optical axis substantially all visible incident light. The mask can further include a portion surrounding at least a portion of the aperture. The portion may be configured to be substantially opaque to visible electromagnetic radiation and be substantially transparent to electromagnetic radiation transmitted from an ocular examination device (e.g., substantially transparent to at least some non-visible electromagnetic radiation with a wavelength between about 750 nm and about 1500 nm).

A contact lens comprising an optically transparent lens body having a concave surface adapted to the patient's eye curvature and a convex surface. The contact lens comprises a light transmitting region and a light blocking region. The light blocking region comprises a plurality of fine holes that are evenly spaced throughout the light blocking region.

A system for custom manufacturing a film to be temporarily applied to lenses of eyewear is provided. The system includes a measuring unit for measuring dimensions of the lenses, a user-interface for receiving user input pertaining to desired properties of the film, and a film-cutting unit for cutting the film according to the dimensions of the lenses. The system can also include a control unit that is configured to receive the dimensions of the lenses from the measuring system, and transmit information pertaining to the dimensions of the lenses to the film-cutting system. The system can also include a payment unit for receiving payment from a user.

Method for designing a pair of ophthalmic lenses and device for optical measurements. The method comprises: determining a distance and placing an object (100) at said distance; placing a frame (4) of reference on the user; for each eye: keeping it uncovered and covering the other eye; placing in front of the eye a screen (5, 6) with a through hole (520, 620); shifting the position of the hole (520, 620) until the user sees said object (100) looking through the hole (520, 620), so that said object (100) is centred in the field of view available; uncovering both eyes; adjusting the positions of the holes (520, 620), to obtain binocular vision; and designing each lens (510, 610) according to said position. The device (1) comprises a frame (2) to which, for each eye, a first plate (51, 61) having a vertical groove (53, 63) and a second plate (52, 62) having a horizontal groove (54, 64) are attached and can be shifted. So that, when the grooves overlap, a pinhole (55, 65) is formed.

Methods in which targeted SEPHS2 disruption/inhibition and/or administration of selenite are used, e.g., in cancers that express SLC7A11.