Methods and systems for registering three-dimensional (3D) CT image data with two-dimensional (2D) fluoroscopic image data using a plurality of markers are disclosed. In the methods and systems, a lateral angle and a cranial angle are searched for and a roll angle is computed. 3D translation coordinates are also computed. The calculated roll angle and 3D translation coordinates are computed for a predetermined number of times successively. After performing the calculations, the 3D CT image data is overlaid on the 2D fluoroscopic image data based on the lateral angle, the cranial angle, the roll angle, and the 3D translation coordinates.

A method for imaging involves scanning an anatomical object within a patient and capturing reflected IR light with a plurality of cameras that are separate from the scanner. The IR images captured by the IR cameras are associated together to create an integrated image based on parallax between the IR cameras and the scanner. The integrated image is associated with a separate or optical light image of the anatomical object to generate an intra-operative 3D image that can be created in real-time. Systems for effectuating such imaging may include multiple surgical instruments supporting various cameras positioned to capture different fields of view and to increase parallax.

A medical image display apparatus for displaying medical images of a lung on a screen includes a network interface receiving positional information of a navigation instrument from a position sensor of the navigation instrument, a video stream from an optical sensor of the navigation instrument, and medical images from an imaging device, a memory storing a plurality of medical images and instructions, a processor executing the instructions, and a display dynamically displaying images on the screen. The instructions, when executed by the processor, cause the medical image display apparatus to determine whether status information indicates a pathway reviewing mode, a target management mode, or a navigation mode. The instructions, when executed by the processor, further cause the display to dynamically select and update images, which are displayed on the screen, among the plurality of medical images based on the positional information of the navigation instrument and status information.

The disclosure relates to a system and method for image reconstruction. The method may include the steps of: obtaining raw data corresponding to radiation rays within a volume, determining a radiation ray passing a plurality of voxels, grouping the voxels into a plurality of subsets such that at least some subset of voxels are sequentially loaded into a memory, and performing a calculation relating to the sequentially loaded voxels. The radiation ray may be determined based on the raw data. The calculation may be performed by a plurality of processing threads in a parallel hardware architecture. A processing thread may correspond to a subset of voxels.

A method of modeling lungs of a patient includes acquiring computed tomography data of a patient's lungs, storing a software application within a memory associated with a computer, the computer having a processor configured to execute the software application, executing the software application to differentiate tissue located within the patient's lung using the acquired CT data, generate a 3-D model of the patient's lungs based on the acquired CT data and the differentiated tissue, apply a material property to each tissue of the differentiated tissue within the generated 3-D model, generate a mesh of the 3-D model of the patient's lungs, calculate a displacement of the patient's lungs in a collapsed state based on the material property applied to the differentiated tissue and the generated mesh of the generated 3-D model, and display a collapsed lung model of the patient's lungs based on the calculated displacement of the patient's lungs.

A heterogeneous population of cells are separated and collected according to a method. The heterogeneous population of cells in a paramagnetic medium are placed in a fluidic channel in which the fluidic channel comprises two or more outlets. The heterogeneous population of cells in the fluidic channel are separated based on differences in magnetic susceptibility and density of the heterogeneous population of cells. Fluid comprising the separated cells is withdrawn from the two or more outlets using variable flow rates by fluidic pumps at respective ones of the two or more outlets simultaneously to fractionalize the fluid comprising the separated cells across the two or more outlets by manipulation of the variable flow rates relative to one another.

A method for imaging involves scanning an anatomical object within a patient and capturing reflected IR light with a plurality of cameras that are separate from the scanner. The IR images captured by the IR cameras are associated together to create an integrated image based on parallax between the IR cameras and the scanner. The integrated image is associated with a separate or optical light image of the anatomical object to generate an intra-operative 3D image that can be created in real-time. Systems for effectuating such imaging may include multiple surgical instruments supporting various cameras positioned to capture different fields of view and to increase parallax.

An x-ray imaging apparatus and associated methods are provided to execute multi-pass imaging scans for improved quality and workflow. An imaging scan can be segmented into multiple passes that are faster than the full imaging scan. Data received by an initial scan pass can be utilized early in the workflow and of sufficient quality for treatment setup, including while the another scan pass is executed to generate data needed for higher quality images, which may be needed for treatment planning. In one embodiment, a data acquisition and reconstruction technique is used when the detector is offset in the channel and/or axial direction for a large FOV during multiple passes.

Methods and systems for computed tomography provide advances in efficiency. The methods operating within the parallel-beam geometry, rather than a divergent beam geometry, for the majority of the operations. In back projection methods perform digital image coordinate transformations on selected intermediate-images, the parameters of one or more coordinate transformations being chosen such that Fourier spectral support of the intermediate-image is modified so that a region of interest has an increased extent along one or more coordinate direction and the aggregates of the intermediate-images can be represented with a desired accuracy by sparse samples. Forward projection methods perform digital image coordinate transformations on an input image to produce multiple intermediate-images, the parameters of one or more coordinate transformations being chosen such that Fourier spectral support of an intermediate-image being produced is modified so that a region of interest has a reduced extent along one or more coordinate direction and the intermediate-images can be represented with a desired accuracy by sparse samples.

An imaging method. The method comprises the following steps: determining a target by identifying target-related position information or characteristic information (S101); implementing a two-dimensional scan of the target to collect image data of the target in a three-dimensional space (S102); processing, during the scanning, and on a real-time basis, the image data and relevant spatial information to obtain a plurality of image contents of the target, and displaying the image content on a real-time basis (S103); and arranging the plurality of image contents in an incremental sequence to form an image of the target (S104). The imaging method prevents collection of unusable image information, shortens image data collection time, and increases the speed of an imaging process. The application further provides an imaging device.