Systems and methods are disclosed for an apparatus and method for practicing injection techniques through an injectable apparatus. The injectable apparatus may contain a camera that is configured to detect the intensity and color of light attenuated from a testing tool after it is injected into a simulated human or animal body parts. A training tool may be connected to a user display device to generate a display of the injection apparatus as well as the performance parameters of a trainee.

An apparatus and method according to which a patient simulator is used to simulate a human patient's breathing pattern, the patient simulator including a simulated respiratory system and a simulated airway system. The simulated respiratory system includes a lung valve, a simulated lung in communication with the lung valve, and a breathing pump including a cylinder and a piston dividing the cylinder into first and second chambers, the first chamber being in communication with the lung valve via at least a first flow path, and the second chamber being in communication with the lung valve via at least a second flow path. The simulated airway system is configured to be in communication with the second chamber of the breathing pump via at least a third flow path. In several exemplary embodiments, simulating, using the patient simulator, the human patient's breathing pattern comprises reciprocating the piston within the cylinder.

The present disclosure is directed to an anatomical model and methods for using the same. The anatomical model of the present disclosure includes a plurality of simulated bodily structures that emulate the naturally occurring structures (e.g., organs, bones, and tissue) of the human body. The anatomical model of the present disclosure can be used to simulate clinical conditions observed in infant subjects and carry out medical procedures and interventions commonly practiced by clinicians under real-life conditions.

A phantom for simulating fetal heartbeat. The phantom includes a housing and a fetal heartbeat simulator. The housing has an exterior shaped like a female human pelvic region and surrounds an interior. The fetal heartbeat simulator includes a tube having a proximal end and a distal end, the distal end being positioned within the interior of the housing. The tube is filled with a first fluid having a first compressibility. A second fluid, having a compressibility that is greater than the compressibility of the first fluid, is disposed at the distal end of the tube. A pressure mechanism operably coupled to the proximal end of the tube is configured to selectively compress and decompress the first and second fluids.

A patient simulator including one or more simulated limbs or limb portions and a simulated torso. The simulated torso includes an upper torso bracket, a lower torso bracket, and an articulation joint via which the upper and lower torso brackets are pivotably connected. Each of the one or more simulated limbs or limb portions is connected, at least indirectly, to the upper torso bracket or the lower torso bracket. The patient simulator may further include a simulated head or head portion connected, at least indirectly, to the upper torso bracket. The one or more simulated limbs or limb portions may include one or more simulated arms or arm portions connected, at least indirectly, to the upper torso bracket. Additionally, or alternatively, the one or more simulated limbs or limb portions may include one or more simulated legs or leg portions connected, at least indirectly, to the lower torso bracket.

Simulated tissue structures and methods of manufacturing are provided. The simulated tissue structures are particularly useful for placement inside abdominal simulators for practicing laparoscopic surgical techniques. One simulated tissue structure includes a combination of two materials that are attached together wherein one of the materials forms a hollow anatomical structure configured to contain the other material. The two materials are attached in an anatomically advantageous manner such that the inner surface of the outer material closely conforms to the outer surface of the inner material. Another simulated tissue structure includes a plurality of layers wherein at least one layer is applied by printing the layer with at least one stencil to impart one or more functional characteristic to the simulated tissue structure.

An ultrasound simulation method for rendering an ultrasound image of an anatomy model, comprises acquiring, with at least one model sensor, a position and/or orientation of the model; acquiring, with at least one probe replicate sensor, a position and/or orientation of an ultrasound imaging probe replicate, the ultrasound imaging probe replicate interacting with low friction with at least one anatomy model surface, the model surface being deformed by the pressure of the ultrasound imaging probe replicate; aligning a VR/AR model to the tracked position and orientation of the anatomy model and the ultrasound imaging probe replicate; interpolating a 2D ultrasound slice by sampling through a standard reconstructed 3D ultrasound volume, as a function of the tracked position and orientation of the anatomy model and the ultrasound imaging probe replicate.

An ultrasound simulation method for rendering an ultrasound image of an anatomy model, comprises acquiring, with at least one model sensor, a position and/or orientation of the model; acquiring, with at least one probe replicate sensor, a position and/or orientation of an ultrasound imaging probe replicate, the ultrasound imaging probe replicate interacting with low friction with at least one anatomy model surface, the model surface being deformed by the pressure of the ultrasound imaging probe replicate; aligning a VR/AR model to the tracked position and orientation of the anatomy model and the ultrasound imaging probe replicate; interpolating a 2D ultrasound slice by sampling through a standard reconstructed 3D ultrasound volume, as a function of the tracked position and orientation of the anatomy model and the ultrasound imaging probe replicate.

Systems and methods are disclosed for an apparatus and method for practicing injection techniques through an injectable apparatus. The injectable apparatus may contain a camera that is configured to detect the intensity and color of light attenuated from a testing tool after it is injected into a simulated human or animal body parts. A training tool may be connected to a user display device to generate a display of the injection apparatus as well as the performance parameters of a trainee.

The method involves computationally modeling a placenta by simulating physical placenta models with computational in silico models. The simulated data is compared with actual data from the physical models, and the simulation is iterated until a match is achieved. The method may also include calibrating diffusion parameters for testing substances, and configuring the models for analyzing instances of fluid-induced shear and substance transport. The simulated data may be used to obtain maternal-fetal pharmacokinetic in silico placenta models, and the method may be used to obtain predictions for time-dependent concentrations of molecules in fetal circulation. The computational models may consider instances of fluid-diffusive transport and carrier-mediated transport in calculations and determinations of transport characteristics and values of different testing substances.