Devices and methods for impinging light on tissue to induce one or more biological effects, and more particularly enhanced testing and characterization techniques for phototherapeutic light treatments are disclosed. Such testing and characterization techniques may be particularly useful in the evaluation and development of light-based treatments for various infectious diseases, including multiple variants of SARS-CoV-2. In particular aspects, testing and characterization techniques are related to the direct testing of differentiated tissue models of human airway epithelia that have been exposed to various pathogens. Phototherapeutic light treatments and corresponding treatment protocols for light are also described that not only inactivate SARS-COV-2 variants in cell-free suspensions, but also inhibit SARS-CoV-2 infections at multiple stages of infection in tissue models of human airway epithelia in a variant-agnostic manner.

An interactive mixed reality simulator is provided that includes a virtual 3D model of internal or hidden features of an object; a physical model or object being interacted with; and a tracked instrument used to interact with the physical object. The tracked instrument can be used to simulate or visualize interactions with internal features of the physical object represented by the physical model. In certain embodiments, one or more of the internal features can be present in the physical model. In another embodiment, some internal features do not have a physical presence within the physical model.

An embodiment includes a system comprising: an artery, a vein, and a nerve; a first length of tubing adjacent at least one of the vein, artery, and nerve; a second length of tubing to couple to the first length of tubing; and a pump comprising a number of actuators; wherein when the system when operating is configured such that (b)(i) the second length of tubing couples to at least one of the number of actuators, (b)(ii) ends of the first and second lengths of tubing are closed, (b)(iii) a second end of the first length of tubing is operatively coupled to a second end of the second length of tubing, (b)(v) the pump pulsates fluid within the first length of tubing in response to the number of actuators intermittently contacting the second length of tubing.

A vascular access training simulator system for training intravascular insertion of a medical device is disclosed. The vascular access training simulator system includes an anatomical training model having clinically relevant ultrasonic properties representative of ultrasonic properties of a human body site for ultrasound imaging. The training model includes a transparent housing, a transparent simulated tissue, at least one simulated blood vessel suspended in the tissue, and a layer of simulated skin covering the housing and the tissue. A first imaging device is records a first video showing a view of an insertion site outside of the simulated skin. A second imaging device records a second video showing the simulated blood vessel through the transparent simulated tissue. A third imaging device is shows an ultrasound view of the simulated blood vessel and the simulated tissue. A monitor displays a composite view of all three videos simultaneously on a single screen.

Disclosed herein is a device for modeling properties of an ear. The device includes an artificial tympanic membrane and a housing coupled to the artificial tympanic membrane. The housing defines an interior portion coupled to an interior surface of the artificial tympanic membrane. The interior portion has an adjustable volume or an adjustable type of fluid and an adjustable gas pressure. Adjustment of the volume or type of fluid and the gas pressure changes a membrane movement to produce selected movement properties according to a mobility scale.

Aspects of the technology described herein relate to operator processing devices and instructor processing device for tele-medicine. The instructor processing device may be configured to receive, from an instruction interface, a selection of an instruction for moving an ultrasound device. The operator processing device may be configured to determine a pose of the ultrasound device relative to the operator processing device. The instructor processing device and the operator processing device may be configured to display in an operator video, based on the pose of the ultrasound device relative to the operator processing device and based on the selected instruction, a directional indicator for moving the ultrasound device. The instructor processing device may also be configured to display, based on the pose of the ultrasound device relative to the operator processing device, orientation indicators in the instruction interface and/or the operator video.

An anatomical model includes a first container, a second container disposed within the first container, and a third container disposed within the second container. The second container and the third container simulate components of kidney anatomy, and the model includes ballistics gel to improve echogenicity during an ultrasound-guided training procedure using the model.

An electronic apparatus and method for medical examination of human body using haptics is provided. The electronic apparatus controls a first head-mounted display to render a 3D model of an anatomical portion of the body of a human subject. The rendered 3D model includes a region corresponding to defect portion in the anatomical portion. The electronic apparatus transmits a touch input to wearable sensor in contact with the anatomical portion. Such an input corresponds to a human touch on the region of the rendered 3D model. The electronic apparatus receives, based on the touch input, bio-signals associated with the defect portion via the wearable sensor. The bio-signals include physiological signals and somatic sensation information associated with the defect portion. As a response to the human touch, the electronic apparatus controls a wearable haptic device to generate a haptic feedback based on the received set of bio-signals.

Disclosed herein is a medical system (100, 300, 500) comprising: a memory (110) storing machine executable instructions, at least one set of predetermined coordinates (124), and a position identifying algorithm (122). The position identifying algorithm is configured for outputting a set of current coordinates (128) for each of the at least one set of predetermined coordinates in response to receiving a current image descriptive of an object (306, 310). The execution of machine executable instructions (120) causes a computational system (104) to repeatedly receive (200) a current image (126) from a camera system (304). The execution of machine executable instructions (120) causes a computational system (104) to perform the following for the current image: receive (202) the set of current coordinates for each of the at least one set of predetermined coordinates in response to inputting the current image into the position identifying algorithm; calculate (204) a positional difference (130) between the at least one set of predetermined coordinates and its set of current coordinates; calculate (206) a one-dimensional value (134) from positional difference using an objective function; and provide (208) a one-dimensional position indicator (136, 314, 600, 602, 608, 800, 900, 1002) for each of and controlled by each one-dimensional value in real time using a user interface (108, 308, 416, 418).

A method for generating a simulated medical image of a manikin part, comprising: detecting an initiation of a procedural step being performed during a simulated surgical operation; determining a standard position for a virtual medical probe corresponding to the procedural step; determining a desirable position for the virtual medical probe based on a starting position for the probe and an actual position of a tip of a medical tool in order for a virtual field of view of the probe to intersect the tip of the medical tool, the standard position being used as the starting position; generating an simulated medical image of the manikin part according to the desirable position, the simulated medical image comprising a representation of the tip of the medical tool and the representation of a region of the manikin part surrounding the tip of the medical tool; and providing the image for display.