In one aspect, a compact augmented permeation system (CAPS) assembly includes a housing defining an interior cavity. The housing further defines a gas inlet for receiving gas within the interior cavity and a gas outlet for expelling the gas from the interior cavity. Additionally, the CAPS assembly includes a gas-permeable membrane positioned within the housing and defining a system boundary across the interior cavity such that gas received within the interior cavity via the gas inlet permeates through the gas-permeable membrane before being expelled from the interior cavity via the gas outlet.

A passively cooled stackable nuclear waste storage system may include a pair of vertically stacked radiation-shielded nuclear waste storage casks. Each cask has a cavity which holds a nuclear waste canister containing spent nuclear fuel or other high-level radioactive wastes. The lower cask may be founded on an above-grade concrete pad. The upper cask is vertically stacked on and detachably coupled to the lower cask. The upper cask comprises a perforated baseplate which establishes fluid communication between cavities of both casks and is configured to prevent radiation shine. One or both casks may include air inlet vents configured to draw ambient ventilation air into each respective cask cavity for cooling the nuclear waste. In operation, air is drawn inward into each cask cavity independently. Air heated in the lower cask rises into the upper cask where it mixes with air drawn into the upper cask and is returned to atmosphere.

A passively cooled stackable nuclear waste storage system may include a pair of vertically stacked radiation-shielded nuclear waste storage casks. Each cask has a cavity which holds a nuclear waste canister containing spent nuclear fuel or other high-level radioactive wastes. The lower cask may be founded on an above-grade concrete pad. The upper cask is vertically stacked on and detachably coupled to the lower cask. The upper cask comprises a perforated baseplate which establishes fluid communication between cavities of both casks and is configured to prevent radiation shine. One or both casks may include air inlet vents configured to draw ambient ventilation air into each respective cask cavity for cooling the nuclear waste. In operation, air is drawn inward into each cask cavity independently. Air heated in the lower cask rises into the upper cask where it mixes with air drawn into the upper cask and is returned to atmosphere.

The present invention is directed to new and improved industrial containment bags wherein the improvement comprises providing methods and technologies for improving the integrity of such bags during processes designed for lifting, transporting storing and/or disposing of the same. In certain embodiments, the improvement includes providing methods and technologies for improving the sealing capabilities of the bag's closure systems. In other embodiments, the improvement includes providing methods and technologies for assessing the load balance of materials being contained in such industrial containment bags; and thereafter, compensating for any significant load imbalances. The present invention is also directed to methods of manufacturing, using, filling, lifting, transporting, storing, and/or disposing of such new and improved industrial containment bags.

The present invention is directed to new and improved industrial containment bags wherein the improvement comprises providing methods and technologies for improving the integrity of such bags during processes designed for lifting, transporting storing and/or disposing of the same. In certain embodiments, the improvement includes providing methods and technologies for improving the sealing capabilities of the bag's closure systems. In other embodiments, the improvement includes providing methods and technologies for assessing the load balance of materials being contained in such industrial containment bags; and thereafter, compensating for any significant load imbalances. The present invention is also directed to methods of manufacturing, using, filling, lifting, transporting, storing, and/or disposing of such new and improved industrial containment bags.

The methods and compositions described herein address the need in the art by providing compositions and methods for a therapy with an antibody that is specifically targeted to and/or retained intra- or peri-tumorally, limiting systemic exposure and reducing side-effects. Accordingly, aspects of the disclosure relate to a composition comprising an immunotherapeutic antibody operatively linked to an extracellular matrix (ECM)-affinity peptide. An ECM-affinity peptide is one that has affinity for an extracellular matrix protein.

The methods and compositions described herein address the need in the art by providing compositions and methods for a therapy with an antibody that is specifically targeted to and/or retained intra- or peri-tumorally, limiting systemic exposure and reducing side-effects. Accordingly, aspects of the disclosure relate to a composition comprising an immunotherapeutic antibody operatively linked to an extracellular matrix (ECM)-affinity peptide. An ECM-affinity peptide is one that has affinity for an extracellular matrix protein.

A container system for radioactive waste and method for using the same is provided. The system includes a canister configured for holding radioactive waste and a lid system. In one embodiment, the lid system comprises a two-part lid assembly including a confinement lid and a shielded lifting lid. The confinement lid is detachably mounted to the confinement lid. In use, the lifting lid supports the confinement lid for lifting and placement on the canister. The lifting lid further shields operators while the confinement lid is mounted to the canister. Thereafter, the lifting lid is removed and may be reused for confinement lid mountings on other canisters. In one embodiment, the confinement lid is bolted to the canister. The canister may be disposed in a protective overpack for transport and storage.

A container system for radioactive waste and method for using the same is provided. The system includes a canister configured for holding radioactive waste and a lid system. In one embodiment, the lid system comprises a two-part lid assembly including a confinement lid and a shielded lifting lid. The confinement lid is detachably mounted to the confinement lid. In use, the lifting lid supports the confinement lid for lifting and placement on the canister. The lifting lid further shields operators while the confinement lid is mounted to the canister. Thereafter, the lifting lid is removed and may be reused for confinement lid mountings on other canisters. In one embodiment, the confinement lid is bolted to the canister. The canister may be disposed in a protective overpack for transport and storage.

A hazardous material storage system includes a drillhole extending into the Earth and including an entry at least proximate a terranean surface. The drillhole includes a substantially vertical portion, a curved portion, and a horizontal portion that includes a hazardous waste repository formed within a first portion of the horizontal portion of the drillhole, the hazardous waste repository vertically isolated, by a rock formation, from a subterranean zone that includes mobile water, and a safety runway formed within a second portion of the horizontal portion exclusive of the hazardous waste repository and adjacent the curved portion, the safety runway defined by a particular length.