Improved optical coherence tomography systems and methods to measure thickness of the retina are presented. The systems may be compact, handheld, provide in-home monitoring, allow the patient to measure himself or herself, and be robust enough to be dropped while still measuring the retina reliably.

The invention relates to an interferometric method, in which the light scattered by an object is imaged onto an electronic camera, wherein a sample light component is assigned to scattering sites on a sectional face in the interior of the object. This sample light component can he separated from the contributions of the other sample light components by processing of the camera image and leads to a sectional image. A particular advantage of the invention lies in the fact that multiple parallel sectional faces can be exposed sequentially at predetermined intervals from each other in the interior of the object. Such a sequence of sectional images can be used to calculate a solid model of the object.

The invention is applicable in particular to the live retina and allows a three-dimensional retina scan within a few seconds with a cost-effective and, if necessary, hand-held device.

Application options are in the fields of ophthalmology and in biometry.

Provided is a common-path optical fiber-based handheld parallel optical coherence tomography (OCT) apparatus, including a probe configured to receive the light from a broadband light source and illuminate a measurement target, wherein the probe may include an inner space through which the light passes, a collimator configured to collimate the light incident to the inner space, a diffraction grating configured to diffract the light having passed through the collimator, a galvanometer scanner configured to reflect the light having passed through the diffraction grating, an objective lens configured to concentrate the reflected light on a focal point, and an interferer configured to acquire an interfered light by reflecting at least a portion of the light having passed through the objective lens.

Provided is a common-path optical fiber-based handheld parallel optical coherence tomography (OCT) apparatus

The present invention provides a novel simple, portable, compact and inexpensive approach for interferometric optical thickness measurements that can be easily incorporated into an existing microscope (or other imaging systems) with existing cameras. According to the invention, the interferometric device provides a substantially stable, easy to align common path interferometric geometry, while eliminating a need for controllably changing the optical path of the beam. To this end, the inexpensive and easy to align interferometric device of the invention is configured such that it applies the principles of the interferometric measurements to a sample beam only, being a single input into the interferometric device.

Optical coherence tomography imaging systems and methods are disclosed. According to an aspect, an optical coherence tomography imaging system includes a scanner configured to obtain images and to convert the images to electrical signals. The system also includes a computing device comprising an OCT module configured to receive the electrical signals, to apply an OCT imaging technique, and to generate imaging data.

The present invention provides a novel simple, portable, compact and inexpensive approach for interferometric optical thickness measurements that can be easily incorporated into an existing microscope (or other imaging systems) with existing cameras. According to the invention, the interferometric device provides a substantially stable, easy to align common path interferometric geometry, while eliminating a need for controllably changing the optical path of the beam. To this end, the inexpensive and easy to align interferometric device of the invention is configured such that it applies the principles of the interferometric measurements to a sample beam only, being a single input into the interferometric device.

A compact and portable apparatus for measuring properties of objects utilizing a fiber optic Sagnac interferometer is enabled. The fiber optic Sagnac interferometer may be a double differential Sagnac interferometer. The interferometer core may be implemented with fiber optic components including polarization maintaining optical fiber, and by utilizing an auto-balanced avalanche photodetector. An optical switch may be incorporated to maintain relatively low average probe signal power while allowing optimal peak probe signal power. The compact and portable apparatus may be configured to measure ultrasonic vibrations, a displacement of an object surface in response to ultrasonic vibrations, and/or a vibration speed of the object surface. A wideband light source may be amplified and stabilized. A sensor head of the interferometer may incorporate a collimator adjustable to block a central portion of the projected probe beam thereby at least in part enabling in-plane and out-of-plane measurements.

Optical coherence tomography imaging systems and methods are disclosed. According to an aspect, an optical coherence tomography imaging system includes a scanner configured to obtain images and to convert the images to electrical signals. The system also includes a computing device comprising an OCT module configured to receive the electrical signals, to apply an OCT imaging technique, and to generate imaging data.

The present invention provides a novel simple, portable, compact and inexpensive approach for interferometric optical thickness measurements that can be easily incorporated into an existing microscope (or other imaging systems) with existing cameras. According to the invention, the interferometric device provides a substantially stable, easy to align common path interferometric geometry, while eliminating a need for controllably changing the optical path of the beam. To this end, the inexpensive and easy to align interferometric device of the invention is configured such that it applies the principles of the interferometric measurements to a sample beam only, being a single input into the interferometric device.