In one embodiment there is provided a bottle assembly to dispense a liquid. The assembly includes a bottle, a syringe, a cap and collar. The assembly includes a child-resistant adult-friendly retaining portion to permit the removal of the cap and collar. The syringe is configured to draw liquid from the bottle at a precise dosage and then when the cap and collar is removed the user can expel the liquid.

A multiple dose syringe has a first valve defining a first valve opening pressure and a second valve defining a second valve opening pressure. A storage chamber in fluid communication with the second valve stores multiple doses of a substance therein and includes an outlet for dispensing multiple doses of the stored substance therethrough. A compression surface is movable between first and second positions and defines a compression chamber between the compression surface and the first valve. Movement of the compression surface in a direction from the first position toward the second position dispenses substance in the compression chamber through the first valve and out of the syringe. Movement of the compression surface in a direction from the second position toward the first position causes substance to flow from the storage chamber through the second valve and into the compression chamber.

An apparatus (100) for metered dispensing of a liquid from a container (3) and a spray applicator having the apparatus (100). The apparatus (100) comprises a base body (5) and a nozzle body (16) having an outlet nozzle. The nozzle body (16) is mounted so as to be displaceable relative to the base body (5) from a dispensing to a clamping position. The apparatus (100) comprises a reset spring (14) for moving the nozzle body (16) from the clamping to the dispensing position. The nozzle body (16) and the valve body form a burst chamber (19). By pressure on the trigger mechanism (26), the locking of the valve body (10) is triggered and the spray burst spring (7) presses the valve body (10) in the nozzle direction. A non-return valve is arranged upstream in the valve body. The spray burst chamber is connected to the outlet nozzle.

A dispensing mechanism for delivering a dosage of medicament including a housing having a proximal-distal axis; a plunger rod having a screw thread and configured to advance along the proximal-distal axis relative to the housing; a user-operable push button moveable along the proximal-distal axis relative to the housing; a twist driver threadably engaged with the push button such that movement of the push button towards the distal end of the housing causes rotation of the twist driver about the proximal-distal axis; and a driver engaged with the twist driver such that rotation of the twist driver causes rotation of the driver, the driver also engaged with a portion of the plunger rod such that rotation of the driver causes rotation of the plunger rod, advancing the plunger rod along the proximal-distal axis relative to the housing.

Embodiments described herein generally relate to devices, systems and methods for measuring a volume or number of doses remaining in a drug delivery device that is used for delivering a dose to a patient. In some embodiments, a dose measurement system for measuring the liquid volume in a container includes a light guide disposed and configured to reflect electromagnetic radiation toward the container. The dose measurement system also includes a light guide disposed and configured to emit electromagnetic radiation into the light guide. A plurality of sensors are located in the apparatus that are optically coupleable to the light guide and are disposed and configured to detect the electromagnetic radiation emitted by at least a portion of the light guide. The apparatus also includes a processing unit configured to receive data representing the portion of the detected electromagnetic radiation from each of the plurality of sensors. The processing unit is further operable to convert the received data into a signature representative of the electromagnetic radiation detected by the plurality of sensors.

A dispensing mechanism for delivering a dosage of medicament including a housing having a proximal-distal axis; a plunger rod having a screw thread and configured to advance along the proximal-distal axis relative to the housing; a user-operable push button moveable along the proximal-distal axis relative to the housing; a twist driver threadably engaged with the push button such that movement of the push button towards the distal end of the housing causes rotation of the twist driver about the proximal-distal axis; and a driver engaged with the twist driver such that rotation of the twist driver causes rotation of the driver, the driver also engaged with a portion of the plunger rod such that rotation of the driver causes rotation of the plunger rod, advancing the plunger rod along the proximal-distal axis relative to the housing.

The present invention provides for a method for the treatment of a respiratory disease, disorder or condition, or a viral infection or viral disease, disorder or condition in a subject, the method comprising the step of administering to said subject a medically active liquid in nebulized form by inhalation, wherein the medically active liquid comprises niclosamide or a pharmaceutically acceptable salt thereof and wherein the medically active liquid is administered in nebulized form using an inhalation device.

According to an aspect of the present invention, a liquid dose dispenser 100 is disclosed. The dispenser 100 comprises a main body having a front assembly 138, a mid assembly 148 and a rear assembly 140. The dispenser 100 comprises a reservoir (liquid container) 134, a liquid dispensing tip 136, a lead screw 130 for guiding the screw in the mid assembly 148. It also comprises a cam 126, a nut 128, and a spring element 132 wherein the spring element retracts the lead screw for controlled dispensing of the liquid. The said dispenser is used for dispensing required doses of liquids, solutions, viscous fluids for pharmaceutical, nutraceutical and food applications.

A fluid dispensing system is provided. The fluid dispensing system includes a container formed by a first chamber and a second chamber separated by an internal divider. A stopper element extends through each chamber via a first aperture disposed in the internal divider. A second aperture is disposed in a base of the second chamber, wherein the stopper element is used to selectively allow fluid to flow from the first chamber into the second chamber when the stopper element is in a measuring configuration. When the stopper element is in a dispensing configuration, the first aperture between is closed and the second aperture is opened to allow fluid from the second chamber to flow exterior from the container. In this manner, a measured amount of fluid from the container can be dispensed in a single movement without using a secondary measuring receptacle.

A a fixed quantity discharge device for a liquid container is provided. The device includes a container main body in which contents are accommodated, a pipette part including a pipette tube to suction and discharge the contents accommodated in the container main body, and a support disposed in an upper portion of the container main body and including a coupling part formed in an upper end portion thereof to be coupled to the pipette part, a tube accommodation part extending from the coupling part to an interior of the container main body such that the pipette tube is inserted into or withdrawn from the tube accommodation part, and a contents inflow hole formed in a lower end portion thereof to communicate with the interior of the container main body, wherein, when the pipette part is separated from the support, the contents accommodated in the container main body may be suctioned into the pipette tube.