A measurement system is provided with an array of laser diodes with one or more Bragg reflectors. At least a portion of the light generated by the array is configured to penetrate tissue comprising skin. A detection system configured to: measure a phase shift, and a time-of-flight, of at least a portion of the light from the array of laser diodes reflected from the tissue relative to the portion of the light generated by the array; generate one or more images of the tissue; detect oxy- or deoxy-hemoglobin in the tissue; non-invasively measure blood in blood vessels within or below a dermis layer within the skin; measure one or more physiological parameters based at least in part on the non-invasively measured blood; and measure a variation in the blood or physiological parameter over a period of time.

An active remote sensing system is provided with an array of laser diodes that generate light directed to an object having one or more optical wavelengths that include at least one near-infrared wavelength between 700 nanometers and 2500 nanometers. One of the laser diodes pulses with pulse duration of approximately 0.5 to 2 nanoseconds at repetition rate between one kilohertz and about 100 megahertz. A beam splitter receives the laser light, separates the light into a plurality of spatially separated lights and directs the lights to the object. A detection system includes a photodiode array synchronized to the array of laser diodes and performs a time-of-flight measurement by measuring a temporal distribution of photons received from the object. The time-of-flight measurement is combined with images from a camera system, and the remote sensing system is configured to be coupled to a wearable device, a smart phone or a tablet.

An optical system measures one or more physiological parameters with a wearable device that includes a light emitting diode (LED) source including a driver and a plurality of semiconductor sources that generate an output optical light. One or more lenses deliver a lens output light to tissue of a user. A detection system receives at least a portion of the lens output light reflected from the tissue and generates an output signal having a signal-to-noise ratio. The detection system comprises a plurality of spatially separated detectors and an analog to digital converter. The detection system increases the signal-to-noised ratio by comparing a first signal with the LEDs off to a second signal with the LEDs on. An imaging system including a Bragg reflector is pulsed and has a near infrared wavelength. A beam splitter splits the light into a sample arm and a reference arm to measure time-of-flight.

Techniques, devices and methods for discriminating a target from a background material without optimizing directly on the target are provided. The devices and methods can generate pass bands of single or multiple wavelengths of variable shape and intensity, and can also select and control the shape of the pass band profiles to improve the detection of targets of interest.

An optical system measures one or more physiological parameters with a wearable device that includes a light emitting diode (LED) source including a driver and a plurality of semiconductor sources that generate an output optical light. One or more lenses deliver a lens output light to tissue of a user. A detection system receives at least a portion of the lens output light reflected from the tissue and generates an output signal having a signal-to-noise ratio. The detection system comprises a plurality of spatially separated detectors and an analog to digital converter. The detection system increases the signal-to-noised ratio by comparing a first signal with the LEDs off to a second signal with the LEDs on. An imaging system including a Bragg reflector is pulsed and has a near infrared wavelength. A beam splitter splits the light into a sample arm and a reference arm to measure time-of-flight.

Techniques, devices and methods for discriminating a target from a background material without optimizing directly on the target are provided. The devices and methods can generate pass bands of single or multiple wavelengths of variable shape and intensity, and can also select and control the shape of the pass band profiles to improve the detection of targets of interest.

A measurement system is provided with an array of laser diodes with one or more Bragg reflectors. At least a portion of the light generated by the array is configured to penetrate tissue comprising skin. A detection system configured to: measure a phase shift, and a time-of-flight, of at least a portion of the light from the array of laser diodes reflected from the tissue relative to the portion of the light generated by the array; generate one or more images of the tissue; detect oxy- or deoxy-hemoglobin in the tissue; non-invasively measure blood in blood vessels within or below a dermis layer within the skin; measure one or more physiological parameters based at least in part on the non-invasively measured blood; and measure a variation in the blood or physiological parameter over a period of time.

A diagnostic system is provided with a plurality of semiconductor light emitters, each configured to generate an optical beam, and a beam combiner to generate a multiplexed optical beam. An optical fiber or waveguide communicates at least a portion of the multiplexed optical beam to form an output beam, wherein the output beam is pulsed. A filter, coupled to at least one of a lens and a mirror to receive at least a portion of the output beam, forms an output light. A beam splitter splits the light into a sample arm and a reference arm and directs at least a portion of the sample arm light to a sample. A detection system is configured to receive from the sample at least a portion of reflected sample light, to generate a sample detector output, and to use a lock-in technique with the pulsed output beam.

A measurement system comprises a pulsed laser diode array that includes one or more Bragg reflectors, and wherein the light generated by the array penetrates tissue comprising skin. At least some of the wavelengths of light are in the near infrared. The detection system is synchronized to the laser diode array and comprises an infrared camera and a first receiver comprising a plurality of detectors. The first receiver comprises one or more detector arrays and performs a time-of-flight measurement. The measurement system generates an image, the detection system non-invasively measures blood in blood vessels within or below a dermis layer within the skin based at least in part on near-infrared diffuse reflection from the skin, and the detection system measures absorption of hemoglobin between 700 and 1300 nanometers wavelength range. A processor compares the absorption of hemoglobin between different tissue spatial locations, and the measurement system processes the time-of-flight measurement.

Object: To provide a remote substance identification device that can identify an unidentified substance, such as a harmful substance, from a remote location. Solution: Provided are a remote substance identification device and method, the device comprising a laser device 10 that emits a laser beam to an irradiated space; a wavelength conversion device 20 that converts a wavelength of the laser beam emitted from the laser device into a plurality of different wavelengths and that emits laser beams of the different wavelengths to the irradiated space; a light collecting-detecting device 30, 40, 50 that collects and detects resonance Raman-scattered light generated from an irradiated object due to resonance Raman scattering; and a processor 60 that identifies the irradiated object on the basis of a result detected by the collecting-detecting device 30, 40, 50.