The application relates to a sample holder (110) and a system (100). The application also relates to a method for processing a biological sample (S) and use of the sample holder or of the system in an analytical method or a diagnostic method. The sample holder (110) comprises a tubular member (111) with a wall that is at least locally transparent and at least locally permeable for reagents, wherein the tubular member consists at least partially of a transparent material.

A system for generating data relating to a tissue core comprises a core needle biopsy module configured to obtain a tissue core from a locus within the body, and a tissue disintegration module operably connected to the core needle biopsy module and configured to receive a tissue core from the core needle biopsy module and convert at least a portion of the tissue core into gaseous tissue molecules. The system also comprises first vacuum pump means configured to convey a tissue core from the needle biopsy module to the tissue disintegration module, and second vacuum pump means configured to convey gaseous tissue molecules from the tissue disintegration module to an analyser module.

A system for generating data relating to a tissue core comprises a core needle biopsy module configured to obtain a tissue core from a locus within the body, and a tissue disintegration module operably connected to the core needle biopsy module and configured to receive a tissue core from the core needle biopsy module and convert at least a portion of the tissue core into gaseous tissue molecules. The system also comprises first vacuum pump means configured to convey a tissue core from the needle biopsy module to the tissue disintegration module, and second vacuum pump means configured to convey gaseous tissue molecules from the tissue disintegration module to an analyser module.

The present invention is drawn to devices and systems for allergen detection in a sample. The allergen detection system includes a sampler, a disposable analysis cartridge and a detection device with an optimized optical system. In some embodiments, the allergen detection utilizes aptamer nucleic acid molecules as detection agents. In some embodiments, the nucleic acids are conjugated to magnetic beads or solid surfaces such as glasses, microwells and microchips.

A method for generating material test samples for conducting material tests of a legacy steam turbine rotor having an inter-blade region rotor surface, and an inlet region rotor surface adjoining the inter-blade region rotor surface. The method includes forming an annular ring of rotor material in the sample area and forming a material test sample from a portion of the annular ring. Also described is a legacy steam turbine rotor including an inter-blade region rotor surface, and an inlet region rotor surface adjoining the inter-blade region rotor surface. The steam turbine rotor having a groove formed therein, and wherein the groove is machined to enable removal of material from the steam turbine rotor to form samples configured to enable at least one of conducting material property tests and operating the improved legacy steam turbine rotor at an expanded thermal stress compared to the legacy steam turbine rotor.

A method for generating material test samples for conducting material tests of a legacy steam turbine rotor having an inter-blade region rotor surface, and an inlet region rotor surface adjoining the inter-blade region rotor surface. The method includes forming an annular ring of rotor material in the sample area and forming a material test sample from a portion of the annular ring. Also described is a legacy steam turbine rotor including an inter-blade region rotor surface, and an inlet region rotor surface adjoining the inter-blade region rotor surface. The steam turbine rotor having a groove formed therein, and wherein the groove is machined to enable removal of material from the steam turbine rotor to form samples configured to enable at least one of conducting material property tests and operating the improved legacy steam turbine rotor at an expanded thermal stress compared to the legacy steam turbine rotor.

Aspects of the present disclosure relate to a sample collection assembly for a vehicle. The sample collection assembly includes a perforated ground-engaging member of the vehicle and an associated sample collector. For example, a perforated wheel may collect material from terrain under the vehicle as the wheel rotates (e.g., as may result from movement of the vehicle), which may fall through the perforation and into a sample collector disposed thereunder. In some examples, a ground-engaging member may include one or more grousers, paddles, or scoops, among other terrain interaction features, to further increase the amount of material that is collected. Such terrain interaction features may be unidirectional or bidirectional, thereby offering improved sample collection in one or both directions of operation, respectively. In examples, an image capture device or one or more other sensors may be used to monitor sample collection and/or to process data associated therewith.

Aspects of the present disclosure relate to a sample collection assembly for a vehicle. The sample collection assembly includes a perforated ground-engaging member of the vehicle and an associated sample collector. For example, a perforated wheel may collect material from terrain under the vehicle as the wheel rotates (e.g., as may result from movement of the vehicle), which may fall through the perforation and into a sample collector disposed thereunder. In some examples, a ground-engaging member may include one or more grousers, paddles, or scoops, among other terrain interaction features, to further increase the amount of material that is collected. Such terrain interaction features may be unidirectional or bidirectional, thereby offering improved sample collection in one or both directions of operation, respectively. In examples, an image capture device or one or more other sensors may be used to monitor sample collection and/or to process data associated therewith.

The present invention provides a test component extraction module having a first arm, a second arm, and a base. The second arm is connected to the first arm. The base is connected to the second arm and has a suction hole for holding a test component. Wherein a first angle is predetermined between the first arm and the second arm. When the suction hole sucks the test component attached to a surface, and the first arm gradually moves away from the surface, a second angle is between the second arm and the first arm, and the second angle is greater than the first angle.

A method of sampling a multi-layered material and a micro-sampling tool are described. The sampling method includes penetrating a top surface of a material in a component of interest with a micro-cutting tool to a predetermined depth sufficient to include each layer of the multi-layered material and a portion of the base, without cutting through the full depth of the base, under-cutting from the depth of penetration through the base to define a micro-sample of the multi-layered material, and removing the micro-sample with each layer of the multi-layered material intact. The micro-sampler includes a cutting tool calibrated to cut to a depth no greater than 2 mm, and in some aspects, no greater than 200 microns into a multi-layered material, the material having a top surface and a metallic or ceramic base and a container for removing and storing a micro-sample cut from the material with each layer of the multi-layered material and a portion of the base intact.