A saliva sensing device for detecting oral health and/or overall health includes a chemically treated test strip biomarker targeted to identify bacteria in the saliva. A breathalyzer for detecting bacteria in the mouth of a user includes a housing, a sensor, and an analyzer. The sensor is coupled to the housing and extends outwardly therefrom for placing in the mouth of user and for collecting a saliva sample. The analyzer is for testing saliva that contacts the sensor.

A portable device for measuring the concentration of at least one component in a gas exhaled by a breath fluid, including a first chamber located upstream of a measuring vessel and including an inlet through which the exhaled breath fluid enters the first chamber, a second chamber located upstream of the measuring vessel, the second chamber including an inlet leading into the first chamber, an outlet in communication with the measuring vessel and through which some of the exhaled breath fluid passes, and an outlet leading to the ambient air, through which some of the exhaled breath fluid is expelled into the ambient air. Further, the second chamber is located inside or adjacent the first chamber and the outlet to the ambient air leads to the first chamber so some of the exhaled breath fluid enters the second chamber through the inlet of the second chamber.

Apparatus for quantifying the amount of re-breathing due to bedding materials. The re-breathing analyzer applies heated air to the material under test through an exhaust port in a probe and receives return air from an intake port in the probe. The exhaust and intake ports are placed to engage the material under test when the probe is in contact with the material. In one embodiment, the probe has a surface that is exposed through a top surface of a housing for the analyzer whereby the material under test is placed on the top surface for testing. The analyzer includes a differential temperature measuring instrument that determines the temperature of the return air, where an increase of the temperature of the return air above the temperature of the ambient air indicates the presence and quantity of re-breathing due to the material under test.

Described herein are Dirofilarial exhalant signatures and methods of detecting a Dirofilaria signature in a non-blood biological sample, such as exhalant, that can be used to detect Dirofilarial infection in a subject, such as a canine.

The present invention features an optical detection system for SARS-CoV-2 or other pathogens, which includes a specialty mask. The specialty mask incorporates a SERS nanopatch for accumulating pathogenic particles from a wearers breath. When the SERS nanopatch receives incident NIR light, backscattered light from the SERS nanopatch is detected by a receiver and analyzed for a Raman spectral shift. Detection of the Raman spectral signature from the SERS nanopatch allows for determination if SARS-CoV-2 or another pathogen is present. In addition to the mask with a nanostructured surface for collecting pathogenic material, the system includes a laser source directed at the nanostructured surface, a detection system to collect backscattered light, a spectral analysis system to detect Raman shifted light, and an analysis system for determining if SARS-CoV-2 or another pathogen is present. AI image processing may be used to steer the laser beam safely to the nanopatch, avoiding eye contact.

A system for collecting a biological sample from a passenger cabin includes a collector for collecting particulate samples positioned within at least one of an outlet flow path or a recirculation flow path. The system includes at least one of an outflow valve positioned in the outlet flow path downstream from the collector or a HEPA (high efficiency particulate air) filter positioned in the recirculation flow path downstream from the collector. A method for collecting particulates from cabin air includes capturing particulates in at least one of an outlet flow path or a recirculation flow path with a collector for a period of time, removing the collector from at least one of the outlet flow path or the recirculation flow path for testing, and inserting a clean collector into at least one of the outlet flow path or the recirculation flow path for use during another period of time.

A device for collecting aerosol particles in an exhaled air flow. The particles may be aerosol particles such as biomarkers or particles related to drugs or other substances formed or found in the alveoli of the lungs. The device comprises an elongate housing with an inner wall and at least four first type partition walls extending substantially perpendicularly from opposite sides of the inner wall to partly cover the cross-section of the housing. The first type partition walls create a labyrinth shaped flow path to divert air flowing from the inlet towards the outlet of the housing in a direction towards opposite inner walls of the housing so that the particles separate from the air flow and attach on the device. The distance between two opposite first type partition walls is smaller than the transverse width of the housing and increases in the flow direction.

Disclosed herein are embodiments of methods for detecting the presence of and amount of drugs in a sample, particularly a particle sample obtained from a subject. In particular disclosed embodiments, the particle samples are skin particle samples, saliva particle samples, and/or mucous samples isolated from a subject and analyzed using thermal desorption methods combined with a selected detection method.

Methods, apparatuses, and systems associated with aerosol collection devices (such as, but not limited to, breath-aerosol collector devices, breathalyzers) are provided. An example aerosol collection device includes a sample transfer adapter configured to receive a sample and a device body connected to the sample transfer adapter. In some examples, the device body defines a flow channel that guides the sample to a filter component, and the filter component contains a buffer solution.

Described herein are rapid breath testing devices, systems and methods. The device may include a mouthpiece operable to receive air flow from a breath; and a cassette comprising a biosensor and a cassette conduit, the cassette removably connected to the mouthpiece such that at least a sample of the air flow passes through the cassette conduit and over the biosensor. The biosensor may include a plurality of graphene-based sensors and may be operable to detect at least one volatile organic compound in the air flow sample.