A system for collecting and retaining a sample from exhaled breath of a subject for analysis can include a two part housing, a two part trap section, and optionally a boat fitment. Disclosed is a portable fluid sampling device comprising: a housing including a first portion removably attachable to a second portion, the first and second portions being configured to combine to form a chamber therein, the chamber being configured to at least temporarily contain or hold a biological sample therein, at least one of the first portion and the second portion including an inlet, the other of the first portion and the second portion including an outlet, wherein the device further comprises at least one of the following: a) one of the first portion and the second portion including an end having a projection, the other of the first portion and the second portion including an end having a groove, the groove being configured to receive at least a portion of the projection therein; or b) tamper evident means for indicating that the first portion of the housing has previously been separated from the second portion of the housing.

An attachment device for a sample collection device for obtaining samples from exhaled respiratory air includes an inlet tube, a dip tube for discharging the respiratory air from the sample collection device, and at least a portion of a spiral path. The portion runs into an outlet opening which is designed to conduct the respiratory air to the sample collection device.

A low weight portable air sampling device comprising a housing at least partially enclosing an inlet for receiving an air or breath sample; a removable liner coupled to the inlet containing sorbing materials; a micro-pump for regulating air flow within the device; and an outlet for emitting the air or breath sample from the device is described. The device may be used to collect Volatile Organic Compounds (VOCs) of both biotic and abiotic origin.

A chemical extraction apparatus has absorbent material for absorbing or adsorbing volatile chemicals from a breath of a user. The chemical extraction apparatus is positioned within such that breaths from the user flow over the absorbent material thereby causing volatile chemicals in the breaths to absorb or adsorb into the absorbent material. The absorbent material is then analyzed to determine the amount of chemicals absorbed or adsorbed into the absorbent material. Based on such analysis, various diseases or conditions can be detected or diagnosed.

A device for collecting aerosol particles in an exhaled air flow. The particles may be aerosol particles such as biomarkers or particles related to drugs or other substances formed or found in the alveoli of the lungs. The device comprises an elongate housing with an inner wall and at least four first type partition walls extending substantially perpendicularly from opposite sides of the inner wall to partly cover the cross-section of the housing. The first type partition walls create a labyrinth shaped flow path to divert air flowing from the inlet towards the outlet of the housing in a direction towards opposite inner walls of the housing so that the particles separate from the air flow and attach on the device. The distance between two opposite first type partition walls is smaller than the transverse width of the housing and increases in the flow direction.

Among other thing, the present invention provides solution to the problem, particularly, the present invention certain surfaces and certain sample holder to improve the sensitivity, speed, and easy-to-use of an optical signal based assays, such as colorimetric assays or fluorescence assays.

An apparatus for controlling alcohol interlock includes a sensor that senses an environment of a driver's seat and a camera that obtains a face image of a passenger and an image of exhalation of the passenger. A controller activates a start lock mode of a vehicle and determines whether a condition for detecting components of the exhalation of the passenger is satisfied based on the environment of the driver's seat. The controller determines whether the exhalation of the passenger is exhalation of a driver based on the face image of the passenger and the image of the exhalation of the passenger, and determines whether to detect alcohol concentration in the exhalation of the passenger based on the determination result.

The present invention is related to the field of bio/chemical sensing, assays and applications. Particularly, the present invention is related to collecting a small amount of a vapor condensate sample (e.g. the exhaled breath condensate (EBC) from a subject of a volume as small as 10 fL (femto-Liter) in a single drop), preventing or significantly reducing an evaporation of the collected vapor condensate sample, analyzing the sample, analyzing the sample by mobile-phone, and performing such collection and analysis by a person without any professionals.

Among other thing, the present invention provides solution to the problem, particularly, the present invention certain surfaces and certain sample holder to improve the sensitivity, speed, and easy-to-use of an optical signal based assays, such as colorimetric assays or fluorescence assays.

A chemical extraction apparatus has absorbent material for absorbing or adsorbing volatile chemicals from a breath of a user. The chemical extraction apparatus is positioned within such that breaths from the user flow over the absorbent material thereby causing volatile chemicals in the breaths to absorb or adsorb into the absorbent material. The absorbent material is then analyzed to determine the amount of chemicals absorbed or adsorbed into the absorbent material. Based on such analysis, various diseases or conditions can be detected or diagnosed.