A disaggregation system includes a console, the console including a housing, a pod holder plate, a motive applicator mounted in the housing and configured to move the pod holder plate. The system further includes a sample pod configured for holding tissue to be disaggregated, where the sample pod includes a collector component configured for mounting to the pod holder plate; a tissue holder sleeve configured for holding tissue to be disaggregated; and a disaggregation screen. Tissue can be disposed in the sample pod, the sample pod configured to be mounted on the pod holder plate of the console, and when the motive applicator moves the pod holder plate with the pod thereon, tissue in the sample pod configured to be disaggregated into cells.

Tissue and cellular samples can be electrically dissociated into single cells and/or smaller groups of cells. The tissue samples can be housed in a device (which may also include a fluid) with one or more electrodes residing within the device. The device can be used to process one or more tissue samples. An electric field can be established through the device and the tissue samples can be dissociated into single cells and/or smaller groups of cells under the electric field.

Disclosed herein are devices, apparatuses, and methods for grinding of samples. A method includes securing a sample vial in a holder attached to a connecting linkage, the sample vial having a grinding media in the sample vial. The method includes rotating a crank that is operatively coupled to a proximal end of the connecting linkage at a proximal pivot point so that the proximal pivot point undergoes rotational motion. The method includes restricting a distal pivot point of the connecting linkage to a linear path, the distal pivot point near a distal end of the connecting linkage. A result being that the sample vial undergoes a combination of rotational and linear motion.

Method for quantifying the micronutrient profile of Moringa oleifera tree leaves (MOLs) using calibration free laser induced breakdown spectroscopy (CF-LIBS).

A device module for a laboratory device is shown and described. The device module has at least one temperature control medium connection for connecting the device module, as required, to a temperature control medium supply of, in particular, a liquid or gaseous temperature control medium, at least one line connection for connecting, as required, to at least one supply line of the laboratory device for the temperature control medium, and at least one actuator of a control process and/or control loop for controlling and/or regulating at least one temperature in the laboratory device.

The invention discloses a method for obtaining the geometrical and mechanical parameters of rock samples and a holographic scanning system thereof, wherein the system includes an observation mechanism, a multi-scale penetration mechanism, a grinding mechanism, a rock sample installation mechanism arranged on a three-axis precision motion platform, and an industrial computer controlling the operation mode of each mechanism of the platform Indentation/rotary penetration test, pulse echo signal acquisition, three-dimensional surface topography reconstruction, layer by layer grinding and repeated experiments are carried out. The geometric parameters and corresponding mechanical field parameters are obtained by spatial interpolation of the three-dimensional parameter lattice accumulated by several layers of single-layer rock parameters. The holographic scanning system and method can obtain the real spatial distribution of various media in rock samples. Combined with high performance numerical calculation method, it provides a more scientific method for the analysis of rock mechanical properties, failure and instability.

A device to detect pathogens and/or analytes in a test sample is designed to include a core, which may have first and second chambers. The first chamber is designed to accept a combination of a test specimen and a buffer liquid. A piston is designed to slideably engage into the first chamber of the core, wherein the end of the piston may engage with the bottom of the first chamber and be capable of grinding the test specimen. A plunger is designed to slideably engage with the second chamber of the core, and is in fluid communication with the first chamber. An assay section is attached to the core, and is in fluid communication with the second chamber. The assay device is designed to include a test strip that is capable of detecting and indicating the presence of pathogens and/or analytes in the combination of the test sample and buffer liquid.

The disclosure is directed to a sample preparation apparatus for grinding or homogenizing test samples. More specifically, the disclosure relates to grinding samples using rotational and linear motion. Grinding samples can be accomplished with an apparatus with a slider-crank mechanism that is attached to an oscillating connecting linkage. The amplitude of oscillatory motion can be greater than or equal to a length of a sample processing chamber.

A method for producing nanoparticulate compressed tablets/pellets from synthetic and/or natural materials, and compressed tablets/pellets produced using the method for producing nanoparticulate compressed tablets/pellets from synthetic and/or natural materials and to uses thereof.

Methods for determining a weathering index using x-ray diffraction (XRD) data are provided. An exemplary method includes obtaining XRD data of a weathered rock sample, and calculating the weathering index using a formula developed to use the XRD data.