Patent classifications
G01N1/31
Systems and methods for automated preparation of biological specimens
An automated system for processing a sample contained in a liquid sample container includes an automated tool head configured to rotate about a first axis, and to translate along a second axis different than the first axis, an analytic element positioner having an analytic element holder configured to releasably grip an analytic element, and a specimen transfer device carried by the tool head, wherein the tool head is configured to automatically position a working end of the specimen transfer device to obtain a specimen from a sample container held in the sample container holder, and to transfer the obtained specimen to an analytic element held by the analytic element holder, respectively, through one or both of rotation of the tool head about the first axis and translation of the tool head along the second axis.
Integrated System for Preparation of Pathology Samples
An integrated pathology system includes a tissue embedding module configured to embed a tissue sample into an embedding material to prepare a tissue block, a sectioning and slide creating module configured to remove one or more tissue sections from the tissue block and place the one or more tissue sections onto one or more slides, a staining module configured to stain the one or more tissue sections on the slides, and a cover-slipper module configured to place a cover onto the one or more stained tissue sections. The system further includes one or more transfer devices configured to integrate the modules and a processor in communication with the modules for controlling one or more processes performed by the modules and the one or more transfer devices for controlling the integration of the modules.
METHOD AND APPARATUS FOR DRYING BIOLOGICAL SAMPLES
This disclosure pertains to methods and apparatus for drying bio-specimens.
Assay for vapor condensates
The present invention relates to provide, among other things, the methods, devices, and systems that can simply and quickly collecting and analyzing a tiny amount of vapor condensates (e.g. exhaled breath condensate (EBC)).
Assay for vapor condensates
The present invention relates to provide, among other things, the methods, devices, and systems that can simply and quickly collecting and analyzing a tiny amount of vapor condensates (e.g. exhaled breath condensate (EBC)).
Method and Apparatus for Preparing Samples Under Cryogenic Conditions for Imaging or Diffraction Experiments in an Electron Microscope
A method and apparatus for preparing samples for imaging under cryogenic conditions or diffraction experiments under cryogenic conditions in an electron microscope. One version of the method involves: partially submerging a flat sample carrier with sample material vertically into a reservoir containing a cryogenic liquid until all areas with sample material are positioned below the surface of the cryogenic liquid; vitrifying the sample material at least one stream of cryogenic liquid to each considerable side of the sample material on the flat sample carrier at or directly below the surface of the cryogenic liquid in the reservoir; and fully submerging the flat sample carrier with the vitrified sample material into the cryogenic liquid to cool the flat sample carrier to a temperature below about 136 K. Variations of the method and various features of the apparatus are described.
Sample holder for biological samples
The application relates to a sample holder (110) and a system (100). The application also relates to a method for processing a biological sample (S) and use of the sample holder or of the system in an analytical method or a diagnostic method. The sample holder (110) comprises a tubular member (111) with a wall that is at least locally transparent and at least locally permeable for reagents, wherein the tubular member consists at least partially of a transparent material.
Sample holder for biological samples
The application relates to a sample holder (110) and a system (100). The application also relates to a method for processing a biological sample (S) and use of the sample holder or of the system in an analytical method or a diagnostic method. The sample holder (110) comprises a tubular member (111) with a wall that is at least locally transparent and at least locally permeable for reagents, wherein the tubular member consists at least partially of a transparent material.
Sample staining device
A sample staining device, comprising a staining platform provided with a staining solution and cleaning solution supply part; glass slide support structures located on either side of the staining platform and forming a certain clearance between a glass slide and the staining platform; and a glass slide driving mechanism that enables the glass slide to move while maintaining a certain clearance from the staining platform. When said device works, a staining solution is supplied to the staining platform, and a convex liquid surface is formed due to surface tension; when the glass slide moves to the convex liquid surface of the staining solution, the staining solution infiltrates and diffuses in the clearance formed between the staining platform and the glass slide to cover the glass slide so as to stain a sample; and after the glass slide is stained, a cleaning solution is supplied to clean the residual staining solution.
TISSUE PIECE TREATING APPARATUS
The present invention addresses the problem of a tissue piece treating apparatus in which drying in an inside of a treating tank is promoted, compared with conventional tissue piece treating apparatuses, and the gas in the inside of the treating tank is discharged so that a risk of inflammation can be prevented. As a solution, a tissue piece treating apparatus (10) according to the present invention includes: a treating tank (18) in which a tissue piece is housed, and immersion of the tissue piece is performed by a chemical solution being supplied thereto; a communication passage (34) that is connected to the treating tank (18); one or a plurality of chemical solution bottles (24) that are connected to the treating tank (18) through the communication passage (34), and store chemical solutions to be supplied to the treating tank (18); and a pump (60) that causes an inside of the treating tank (18)to be a negative pressure to supply the chemical solution from the chemical solution bottle (24) to the inside of the treating tank (18), and causes the inside of the treating tank (18) to be a positive pressure to discharge the chemical solution from the inside of the treating tank (18) to the chemical solution bottle (24), in which the communication passage (34), which partially branches, includes an outside air port (42) that communicates with an outside air, and is thus configured to be able to supply and discharge the outside air to and from the inside of the treating tank (18) by receiving an action of the pump (60).