G01N1/4022

Specimen preparation apparatus

A lower-side structure forms a specimen chamber in which a specimen base is provided. An upper-side structure forms a nozzle chamber above the specimen chamber. The specimen chamber and the nozzle chamber are separated by a gate valve. In the nozzle chamber, at least a tip opening of a nozzle that ejects a specimen is present. A control device maintains a relationship of gas pressures such that a gas pressure in the specimen chamber is higher than a gas pressure in the nozzle chamber when the lower-side structure and the upper-side structure are in communication with each other.

PORTABLE SENSOR DEVICE FOR RAPID DETECTION OF HEAVYMETAL IONS AND METHODS THEREFOR

Example implementations include a sensor device with a superhydrophobic sensor panel having an abraded first planar surface and a second planar surface opposite to the first planar surface, and a metallic heating element adjacent to the second planar surface of the superhydrophobic sensor panel. Example implementations also include a method of detecting a concentration of heavy metal ions in a solution, by separating a target solute of a target microdroplet from the target micropdroplet, identifying a distribution area of at least one heavy metal ion in an image of the target solute, generating a heavy metal ion concentration quantity based on the distribution area, generating a composite image including an indication of the distribution area, and presenting an indication of at least one of the heavy metal ion concentration quantity and the composite heavy metal ion image. Example implementations also include a method of manufacturing a heavy metal ion sensor device, by abrading a first planar surface of a superhydrophobic sensor panel, depositing a metallic layer on a nonconductive substrate, and contacting the metallic layer to a second planar surface of the sensor panel opposite to the first planar surface.

Sensitivity Traps for Electronic Trace Detection

Embodiments of the present specification provide methods and systems for sensitivity traps that contain a polymer matrix made from an inert polymer material for encapsulation of trace amounts of explosives and narcotics and a suitable plasticizer material, the types and ratios of which may be selected based on type of analyte that is to be used with the sensitivity trap. The plasticizer material functions by breaking up intra and inter-molecular polymer chain interactions resulting in a larger diffusion coefficient of the analyte within the polymer matrix. Therefore, in embodiments, sufficient amounts of plasticizers are added to the sensitivity trap, which also reduces a glass transition temperature of the polymer matrix and the trap.

Methods to analyze hydrocarbon solutions

The present application describes a method to reduce noise and improve data quality when analyzing hydrocarbon compositions with a Quartz Crystal Microbalance (QCM). In some approaches, the methods described in this disclosure remove at least a portion of volatile components from the hydrocarbon composition to be tested with the QCM.

DEVICE FOR REDUCING THE VOLUME OF A SAMPLE, A KIT COMPRISING THE SAME, AND USES THEREOF
20230324267 · 2023-10-12 ·

Disclosed herein is a device for reducing the volume of an aquatic sample, comprising, a substrate; a metal layer disposed above the substrate; a hydrophobic layer disposed above the metal layer having a plurality of assay wells formed therein; and a hydrophilic layer coated on each of the plurality of assay wells. Also encompassed in the present disclosure are a kit comprising the device and a lipoplex containing a liposome and a fluorescence-labeled molecular beacon inside the liposome, and use of the kit in detecting a target nucleic acid in a biological sample.

Particle detection system and method

A particle detector for rapidly detecting and identifying sub 20 nm particles in Ultra Pure Water (UPW) is disclosed. The detector has a nano particle extractor, a nanoparticle collector, and a tracer particle introducer. The extractor limits the size of droplets output to a predetermined size. The extractor includes (1) a liquid sample inlet, (2) a nebulizer connected to the liquid sample inlet (the nebulizer has a gas supply, and an outlet), (3) an impactor arranged to receive material output from the nebulizer, (4) an evaporator connected to the nebulizer and impactor for providing an aerosol at the extractor outlet, and (5) an aerosol connected to the evaporator. The collector us connected to the extractor and has: (1) a collector inlet connected to the aerosol outlet of the extractor, (2) a vapor condensation growth tube connected to the collector inlet, and (3) a repositionable particle capture plate arranged to receive material output from the growth tube at spatially varying positions. The tracer particle introducer is connected to the liquid sample inlet of the extractor. It includes a tracer particle supply connected to a pump which is connected to the extractor. A method for rapid identification of sub−20 nm particles in UPW is also disclosed.

METHODS AND SYSTEMS FOR MANAGING FLUID FLOW IN CONTAINERS

Systems and methods for managing fluid flow in and evaporating solvents from containers are provided. In various embodiments, systems of the present disclosure provide for cap or cover members operable to be provided with vials or containers comprising one or more fluids. The caps are further operable to direct air and gas flow into and out of the containers. In some embodiments, supporting structures and heating elements are provided to enhance and assist various processes.

Method of sample preparation for maldi and automated system therefor

Methods for preparing a biological sample for testing by Maldi where such methods are selected based on sample parameters. Maldi scores are obtained for a range of sample parameters (e.g. McFarland, dispense volume and number of dispenses). From the data, sample preparation parameters can be selected for a biological sample being prepared for Maldi testing. One sample preparation strategy uses multiple dispenses of sample with an intervening drying step, which yields more accurate Maldi scores, particularly for samples at the low range of McFarland values (e.g. below about 2).

Method and system for preserving and obtaining hydrocarbon information from organic-rich rock samples
11774417 · 2023-10-03 ·

Methods and systems to preserve, prepare, extract, and/or analyze hydrocarbons in the pore spaces of or adsorbed in organic-rich rock samples, such as, but not limited to, drill cuttings and drill cores, using one or more combinations of physical energy sources, including, but not limited to, thermal, vapor pressure, and mechanical stress. The collected samples are transported and prepared in low temperature conditions, with parts of subsequent processing at very low temperatures, thereby allowing a fuller measurement of geochemical fingerprints for the extracted hydrocarbons using various analysis tools. More particularly, the treatment and process allows geochemical fingerprinting to very low carbon number ranges.

Preconcentrating of environmental contaminant analytes for ambient ionization mass spectrometry
11798796 · 2023-10-24 · ·

The present disclosure relates to a method and system of preconcentrating analytes in a solution within an emitter for ionization mass spectrometry and analysis.