Described herein are cartridges and devices for operating said cartridges for analyzing a biological sample, such as a blood or saliva sample. Also described herein is an impedance sensor for analyzing a biological sample. Further described herein are methods of determining a cell count or detecting an analyte in a biological sample, which can include transporting the biological sample through a sensor comprising a channel or pore; applying an electrical current or voltage to the channel or pore; detecting an impedance within the channel or pore; and determining a cell count or detecting the analyte based on the detected impedance. Also described herein is an electrowetting electrode array that is configured to transport aqueous solutions using low voltage, such as about 50 volts or less. Further described herein are methods of transporting an aqueous liquid using electrowetting electrodes.

A method for processing a substrate by using fluid flowing through a particle detector is provided. The particle detector is utilized to detect nano-particles contained in fluid. The particle detector includes a substrate and a pair of sensing electrodes disposed on the substrate. The substrate includes nano-pores, wherein the pore size of the nano-pores is greater than the particle size of the nano-particles, allowing the nano-particles contained in the fluid passing through the nano-pores. The pair of sensing electrodes are positioned adjacent to at least one of the nano-pores.

A system and a method for the batch sorting of particles are provided. An example of a batch sorting system includes a microfluidic ejector, a flow channel fluidically coupled to the microfluidic ejector at one end, and a reservoir coupled to an opposite end of the flow channel from the microfluidic ejector. A counter is disposed in the flow channel upstream of the microfluidic ejector to count particles prior to ejection from the microfluidic ejector. An optical sensor is to image the flow channel. A controller is configured to locate a target particle in the flow channel based, at least in part, on the image and capture the target particle in a collection vessel based, at least in part, on a count from the counter.

The disclosure provides a device for high-coverage monitoring of vehicle interior air quality. The device includes at least two types of mobile monitoring vehicles for atmospheric pollutants. At least one type of mobile monitoring vehicles is an optimal group of certain number of vehicles selected from candidate vehicles, by installing air pollution detection equipment on the mobile monitoring vehicles, to monitor air quality of the urban area. A method for selection of the optimal group of certain number of vehicles includes decomposing the road network of the urban area into road segment units (RSUs); initializing a database of RSUs, which comprises RSU numbers, RSU locations, and RSU detection records; counting the traveling route of each candidate vehicle that travels within a certain period of time; recording the number of times that each candidate vehicle passes each RSU.

The present disclosure relates to a sensor arrangement (1) for analyzing substances in a material, comprising a substrate (2), a first reception area (5) for receiving a first material, an electronic component sensor (3), a test area (4) that is in contact with the electronic component sensor (3), and a control device (10). The first reception area (5) and the test area (4) are arranged on the substrate (2). The control device (10) is configured for controlling the first reception area (5) and/or the test area (4) to move a portion of the first material from the first reception area (5) into the test area (4). Further, the present disclosure relates to a method for operating such a sensor arrangement (1).

The present invention comprises methods and systems that use acoustic radiation pressure.

The present invention comprises methods and systems that use acoustic radiation pressure.

According to one embodiment, an analysis chip for detection of particles in a sample liquid includes a substrate, a channel provided on a surface portion of the substrate, a liquid storage portion provided on a part of the channel to store the sample liquid, holes being provided at a bottom portion of the liquid storage portion to connect the liquid storage portion and the channel, and first electrodes provided in the channel or the liquid storage portion.

An aerolysin nanopore or a nanotube is used for the electrical detection of peptides, proteins separated by at least one amino acid and other macromolecules such as polysaccharides or synthetic or natural polymers present in a preparation where said nanopore or nanotube is inserted into a lipid membrane which is subjected to a difference in potential greater than −160 mV, in a reaction medium having an alkali metal halide electrolyte solution with a concentration of less than 6M and at a temperature of less than 40° C., and where said use is intended to differentiate said peptides, proteins and other molecules according to their length and their mass. Application to the sequencing of peptides and other molecules to differentiate them according to their length and mass with an amino acid-level or monomer-level resolution and to medical diagnosis.

An aerolysin nanopore or a nanotube is used for the electrical detection of peptides, proteins separated by at least one amino acid and other macromolecules such as polysaccharides or synthetic or natural polymers present in a preparation where said nanopore or nanotube is inserted into a lipid membrane which is subjected to a difference in potential greater than −160 mV, in a reaction medium having an alkali metal halide electrolyte solution with a concentration of less than 6M and at a temperature of less than 40° C., and where said use is intended to differentiate said peptides, proteins and other molecules according to their length and their mass. Application to the sequencing of peptides and other molecules to differentiate them according to their length and mass with an amino acid-level or monomer-level resolution and to medical diagnosis.