A cell detection method and a cell detection device. The cell detection method includes: dividing a liquid sample into a plurality of droplets in a sample detection region so that each of the plurality of droplets includes fewer than ten cells; and performing optical detection on the plurality of droplets in the sample detection region to determine a target droplet including a target cell from the plurality of droplets.

A microfluidic analyser and a method of using the same is disclosed. The microfluidic analyser comprising a droplet generator, an analyte flow channel in fluid communication with said droplet generator at a first end, wherein said flow channel is configured to allow the droplets to flow in from the first end and exit from a second opposing end, said flow channel receiving at least one illumination channel positioned at a predetermined location between the first and the second end to excite contents of the droplets and said flow channel further comprising a plurality of receiving channels set at predetermined angles to an axis of the flow channel to interrogate at least one optical signal from the illuminated droplet traversing the flow channel and wherein said receiving channels terminate in a signal detector at the distal end away from the flow channel.

Various embodiments are directed to a device for detecting a particle liquid content characteristic comprising: one or more fluid flow device inlets configured to receive at least one fluid sample comprising a first plurality of particles and a second plurality of particles, the device being configured to determine a particle liquid content characteristic based at least in part on a comparison of first particle data and second particle data. In various embodiments, the device may comprise a heating element configured to heat at least a portion of particles within the second fluid sample. In various embodiments, the device may comprise a fluid sensor configured to generate first particle data using an optical scattering operation and a fluid composition sensor configured to generate second particle data using a particle imaging operation. Various embodiments are directed to systems and methods for controlling a fluid flow monitoring system.

In an illustrative configuration, a method for monitoring air quality is disclosed. The method includes accepting analyte gas into a cell and reflecting light rays into the analyte gas repeatedly across the cell into at least one sensor. The light scattered by particulate matter in the analyte gas and amount of spectra-absorption due to presence of a gaseous chemical is then measured. Based on the determined amount of spectra-absorption and the measured scattered light the gaseous chemical is then measured.

Systems and methods for wireless location are disclosed. In one aspect, a method for wireless location includes collecting signal strength values from one or more nodes (e.g., mobile devices) in an area over a time interval. The nodes receive wireless signals from one or more other transmitting nodes, where the signal strength values are representative of the signal strengths of the wireless signals. The method further includes normalizing the collected signal strength values and evaluating respective locations within the area of the nodes based on the normalized signal strength values. In a further aspect, the evaluated locations of the nodes may be used to execute an automated light show over the area, by instructing the nodes to display certain color or pattern at their locations in the area.

A particle analyzer, comprising a source of a substantially nondiffracting light beam; a flow path configured to produce in a flowcell a ribbon-like core stream having a specific cross-sectional aspect ratio; the flowcell being configured to expose a segment of the core stream to the light beam; a detector configured to receive a signal resulting from an interaction of a particle in the core stream with the light beam; a first sorting actuator connected with the flowcell, downstream of the exposed segment of core stream; a plurality of sorting channels in fluid connection with the flow path and downstream of the first actuator; the actuator having multiple actuation states, each state configured to direct at least one part of the core stream to a corresponding channel; a second sorting actuator connected with the flowcell, opposite the first actuator, and operable in coordination with the first actuator.

A microfluidic chip orients and isolates components in a sample fluid mixture by two step focusing, where sheath fluids compress the sample fluid mixture in a sample input channel in one direction, such that the sample fluid mixture becomes a narrower stream bounded by the sheath fluids, and by having the sheath fluids compress the sample fluid mixture in a second direction further downstream, such that the components are compressed and oriented in a selected direction to pass through an interrogation chamber in single file formation for identification and separation by various methods. The isolation mechanism utilizes external, stacked piezoelectric actuator assemblies disposed on a microfluidic chip holder, or piezoelectric actuator assemblies on-chip, so that the actuator assemblies are triggered by an electronic signal to actuate jet chambers on either side of the sample input channel, to jet selected components in the sample input channel into one of the output channels.

Described herein are devices and methods for high throughput purification of particles. In some cases, methods and devices described herein can be used to remove erythrocytes and purify leukocytes and raise the quality of umbilical cord blood and other transplant grafts, thereby significantly improving patient outcomes.

A method and apparatus for particle counting and wavelength or angle performed in combination in order to characterize an aerosol is disclosed. In one example, data regarding particle counting (such as from an optical particle sensor) and data regarding angle or wavelength (such as from an ensemble measurement sensor) may be separately generated, with the separately generated data being analyzed in combination in order to characterize the aerosol. In another example, data regarding particle counting and regarding angle or wavelength may be generated in combination in order to characterize the aerosol.

In some embodiments, a process and system are provided for generating a user interface for classification of a sample image of a cell that includes receiving a sample image of a sample particle from a biological sample and selecting reference images that each portray a reference particle of a biological sample. The reference images can be ordered based on similarity and the reference images can be selected based on the order. The first selected reference image can be aligned with the sample image and expanded such that the adjacent edges of the reference image and sample image are the same. The expanded image can be dynamically filled. The sample image and the expanded reference image can be displayed in a user interface.