A detection device for tiny particles in a liquid is provided. The detection device comprises includes a flow cell, a laser, a scattered light collection device, a photoelectric detector, a fiber Bragg grating and a first optical fiber coupler, wherein scattered light collected by the scattered light collection device is sent to the fiber Bragg grating through the first optical fiber coupler, and reflected light of the fiber Bragg grating after receiving the scattered light is sent to the photoelectric detector through the first optical fiber coupler. The device can eliminate most scattered light generated by the liquid, and reduce the interference of the scattered light of the liquid to scattered light signals generated by the particles, so that the scattered light signals captured by the photoelectric detector are mainly light signals generated by the particles.

An apparatus for sensing particulate matter in a fluid includes a fluid flow conduit fluidically connected to an interaction chamber; a light source positioned to illuminate the interaction chamber; and a light detector assembly positioned to receive light scattered by particulate matter present in the interaction chamber. The light detector assembly includes a light detector; and an optical element, the optical element configured to provide light to the light detector based on an incidence angle of the scattered light.

A mobile monitoring device for monitoring controlled contamination areas may include a motorized mobile structure, a sampling unit, and a central management and control unit. The motorized mobile structure is configured to move within an area to be monitored. The sampling unit is positioned on said mobile structure, and configured to perform sampling operations of air and/or surfaces of said area and obtain sampling data. The central management and control unit is operatively connected to the mobile structure and to said sampling unit. The mobile structure may be controlled by the central unit to reach predefined points of the area to be monitored. The sampling unit may be selectively activated and/or deactivated by said central unit in correspondence with said predefined starting points of said sampling operations.

The present invention is in the field of experimental data acquisition. In particular, the present invention relates to a live-cell imaging method and a corresponding system for acquiring experimental data of one or more biological probes. More specifically, the present invention relates to methods and systems for evaluating an optimized concentration trajectory for administration of a drug, in particular a chemotherapeutic drug.

A calibration apparatus comprises estimation circuitry configured to estimate, based on a calibration factor, an estimated number of cells of a first type in a dyed biological sample containing an unknown number of cells. Determination circuitry determines the actual number of cells of the first type in the dyed biological sample. Processing circuitry adjusts the calibration factor. The estimation circuitry is configured with the processing circuitry to estimate the estimated number of the cells of the first type in the dyed biological sample one or more times, based on a different value of the calibration factor for each of the one or more times, until the estimated number of the cells of the first type approaches the actual number of cells of the first type.

In a bubble measurement device for measuring bubbles moving in a liquid, the bubble measurement device includes a measurement chamber in which the bubbles in the liquid containing solid materials are introduced into the measurement chamber from below the measurement chamber, and providing a transparent slope facing diagonally downward at a position where the introduced bubbles rise, an image capturing device to capture an image of the bubbles passing the transparent slope, an introduction pipe provided below the measurement chamber to introduce the bubbles into the measurement chamber, and a bubble introduction valve that is immersed in the liquid to be measured and performs the introduction and blocking of the bubbles into the introduction pipe.

An inspection device for a pillar shaped honeycomb filter includes: a housing portion that can house a pillar shaped honeycomb filter; an introduction pipe and a discharge pipe through which a gas can flow, each of the introduction pipe and the discharge pipe being connected to the housing portion; a particle generation portion for generating particles; a particle introduction portion for introducing the particles generated by the particle generation portion into the introduction pipe; a gas stirring portion arranged in the introduction pipe on an upstream side of the particle introduction portion in a gas flow direction; and particle counters for measuring the number of particles, the particle counters being arranged in the introduction pipe and the discharge pipe on a downstream side of the particle introduction portion in the gas flow direction.

The present disclosure provides methods, systems, and kits for detecting molecules in a sample with a pre-equilibrium digital immunoassay. The methods and systems provide means for quantifying molecules in a biological sample of minimal volume in short amounts of time.

Disclosed is a method for detecting and/or growing particles, comprising controlling the surface area exposed to the saturator region by monitoring at least one of a depth of the working liquid on the saturator surface, the surface area exposed to the saturator region, or a volume of the working liquid on the saturator surface. Also disclosed is an apparatus or system for detecting and/or growing particles, comprising a fluidics system configured to control the surface area exposed to the saturator region by monitoring at least one of a depth of the working liquid on the saturator surface, the surface area exposed to the saturator region, or a volume of the working liquid on the saturator surface. Certain aspects do not employ one or more porous structures for vapor generation, nor a separate carrier fluid flow or inlet comprising a carrier fluid and vaporized working liquid for combining with the sample flow in the saturator region.

For analyzing a sample containing particles of at least two categories, such as a sample containing blood cells, a particle counter subject to a detection limit is coupled with an analyzer capable of discerning particle number ratios, such as a visual analyzer, and a processor. A first category of particles can be present beyond detection range limits while a second category of particles is present within respective detection range limits. The concentration of the second category of particles is determined by the particle counter. A ratio of counts of the first category to the second category is determined on the analyzer. The concentration of particles in the first category is calculated on the processor based on the ratio and the count or concentration of particles in the second category.