A device (100) for visualization of one or more components in a blood sample is disclosed. In one aspect, the device (100) includes an imaging module (110), wherein the imaging module (110) includes a controllable illumination source (102) capable of emitting light in plurality of discrete angles; a tube lens (105); one or more objective lens (104); and an image capturing module (106). Additionally, the device (100) includes a channel (103) configured to carry the blood sample, wherein the channel (103) is capable of sorting the one or more components in the blood sample.

A system for analysing drops capable of being ejected by a coating product applicator, includes a light source configured to illuminate a drop ejection zone, designated observation zone; a first image acquisition device configured to acquire an image of the observation zone; and an image analyser configured to determine, from the image of the observation zone, the presence of drops at a given distance from the applicator, the size of the drops and the absence of satellite; the light source and the first image acquisition device being situated on a same side of the observation zone.

In a bubble measurement device for measuring bubbles moving in a liquid, the bubble measurement device includes a measurement chamber in which the bubbles in the liquid containing solid materials are introduced into the measurement chamber from below the measurement chamber, and providing a transparent slope facing diagonally downward at a position where the introduced bubbles rise, an image capturing device to capture an image of the bubbles passing the transparent slope, an introduction pipe provided below the measurement chamber to introduce the bubbles into the measurement chamber, and a bubble introduction valve that is immersed in the liquid to be measured and performs the introduction and blocking of the bubbles into the introduction pipe.

The invention provides devices and methods for linked multimodal measurements of individual particles using a mass sensor and an additional sensor.

The present disclosure is related to a method of producing a microfluidic sorting apparatus. The method includes providing an injection-molded substrate comprising a network of channels; bonding an insulating film to an upper surface of the substrate to cover the network of channels; and depositing a conductive film on the insulating film. The substrate can be separated from the conductive film.

Methods of classifying flow cytometer data are provided. Methods of interest include receiving a first gate and flow cytometer data, expanding the first gate to generate a second gate, and determining sets of flow cytometer data encompassed by each of the first gate and the second gate to classify the flow cytometer data. In embodiments, methods also involve recording a subset of the classified flow cytometer data and optionally adjusting the first and/or second gates based on the recorded data. In some cases, the subject methods include sorting particles associated with the classified flow cytometer data based on the first and second gates. Systems and computer-readable storage media for practicing the invention are also provided.

Biosensing platform for simultaneous, multiplexed, high throughput and ultra-sensitive optical detection of biomarkers labelled with plasmonic nanoparticles, the platform being provided with a biosensor, a broadband and continuous spectrum illumination source, an optical detector for simultaneously capturing spatially resolved and spectrally resolved the scattering signal of each individual nanoparticle, an autofocus system and an optical system adapted to collect the scattered signal of the biosensor's surface onto the optical detector, the platform being provided with translation means for the optical system and/or the biosensor, such that the optical system and the biosensor can be displaced relative to each other in the three dimensions, and wherein the processing means are adapted to: i) simultaneously capture spatially and spectrally resolved scattering signals from each nanoparticle individually, and ii) to analyze these signals simultaneously with the capture process.

Disclosed are methods, systems, and articles of manufacture for performing a process on biological samples. An analysis of biological samples in multiple regions of interest in a microfluidic device and a timeline correlated with the analysis may be identified. One or more region-of-interest types for the multiple regions of interest may be determined; and multiple characteristics may be determined for the biological samples based at least in part upon the one or more region-of-interest types. Associated data that respectively correspond to the multiple regions of interest in a user interface for at least a portion of the biological samples in the user interface based at least in part upon the multiple identifiers and the timeline. A count of the biological samples in a region of interest may be determined based at least in part upon a class or type of data using a convolutional neural network (CNN).

An electronically-controlled digital ferrofluidic device is disclosed which employs a network of individually addressable coils in conjunction with one or more movable permanent magnets, where each moveable permanent magnet delivers the designated fluid manipulation-based tasks. The underlying mechanism facilitating fluidic operations is realized by addressable electromagnetic actuation of miniaturized mobile magnets that exert localized magnetic body forces on droplets filled with magnetic nanoparticles. The reconfigurable, contactless, and non-interfering magnetic-field operation properties of the underlying actuation mechanism allow for the integration of passive and active components to implement advanced and diverse operations with high efficiency (e.g., droplet sorting, dispensing, generation, merging, mixing, filtering, and analysis).

A method for operating a blast furnace with which, even in the case where there is an increase in the powder ratio of coke to be charged into the blast furnace, it is possible to achieve the stabilization of blast furnace operation. The method includes blowing air through a tuyere disposed in a lower part of the blast furnace, successively measuring a particle size distribution of coke transported to the blast furnace, and adjusting at least one of a blast volume and a coke ratio in accordance with an index derived from the particle size distribution.