A granular-substance component measuring method comprises steps of emitting detection light to granular substances filled in a space, receiving a reflected light from the granular substances and measuring a component of granular substances by a spectroscopy, and a displacement is given to the granular substances at each measurement, measurements are performed a plurality of times, and measurement results are averaged.

Systems for protein quantitation using a Fabry-Perot interferometer. In one arrangement, a quantitation device includes an infrared source, a sample holder, and a Fabry-Perot interferometer positioned to receive infrared radiation from the source passing through a sample on the sample holder. A band pass optical filter sets the working range of the interferometer, and radiation exiting the interferometer falls on a detector that produces a signal indicating the intensity of the received radiation. A controller causes the interferometer to be tuned to a number of different resonance wavelengths and receives the intensity signals, for determination of an absorbance spectrum.

Systems for protein quantitation using a Fabry-Perot interferometer. In one arrangement, a quantitation device includes an infrared source, a sample holder, and a Fabry-Perot interferometer positioned to receive infrared radiation from the source passing through a sample on the sample holder. A band pass optical filter sets the working range of the interferometer, and radiation exiting the interferometer falls on a detector that produces a signal indicating the intensity of the received radiation. A controller causes the interferometer to be tuned to a number of different resonance wavelengths and receives the intensity signals, for determination of an absorbance spectrum.

Systems for protein quantitation using a Fabry-Perot interferometer. In one arrangement, a quantitation device includes an infrared source, a sample holder, and a Fabry-Perot interferometer positioned to receive infrared radiation from the source passing through a sample on the sample holder. A band pass optical filter sets the working range of the interferometer, and radiation exiting the interferometer falls on a detector that produces a signal indicating the intensity of the received radiation. A controller causes the interferometer to be tuned to a number of different resonance wavelengths and receives the intensity signals, for determination of an absorbance spectrum.

A sample holder for use in an optical microscope is disclosed. The sample holder includes a plasmonic layer defining a periodic array of sub-micron structures wherein the periodic array of sub-micron structures comprise an array of separated plasmonic regions. The regions may be a circle, a torus, an ellipse, a cross, rectangle, square, line, strip. Methods of performing reflection and fluorescence microscopy using such a sample holder and other sample holders are also disclosed.

Systems, devices, and methods for combined wafer and photomask inspection are provided. In some embodiments, chucks are provided, the chucks comprising: a removable insert, wherein the removable insert is configured to support a wafer so that an examination surface of the wafer lies within a focal range when the chuck is in a first configuration, wherein the removable insert is inserted into the chuck in the first configuration; and a first structure forming a recess that has a depth sufficient to support a photomask so that an examination surface of the photomask lies within the focal range when the chuck is in a second configuration, wherein the removable insert is not inserted into the chuck in the second configuration.

A transmissive sampling module used to fix a test object to allow a spectrometer body to obtain optical information of the test object and includes a bearing base, a light emitting element, an adapter element and a sample accommodating device. The bearing base includes a first accommodating tank body. The light emitting element is disposed in the bearing base and used to emit an illumination beam. The adapter element is disposed in the first accommodating tank body and further includes a body portion and an abutting rib extending from the body portion. The body portion and the abutting rib jointly form a second accommodating tank body. The sample accommodating device at least partially surface-contacts with a second tank surface through a second light exit. A spectrometer having the transmissive sampling module is provided.

Systems for protein quantitation using a Fabry-Perot interferometer. In one arrangement, a quantitation device includes an infrared source, a sample holder, and a Fabry-Perot interferometer positioned to receive infrared radiation from the source passing through a sample on the sample holder. A band pass optical filter sets the working range of the interferometer, and radiation exiting the interferometer falls on a detector that produces a signal indicating the intensity of the received radiation. A controller causes the interferometer to be tuned to a number of different resonance wavelengths and receives the intensity signals, for determination of an absorbance spectrum.

A sampling tool for use with an infrared spectrophotometer, and method of use. The sampling tool comprises a bottom plate; and a mesh attached to the bottom plate, the mesh having a plurality of interstitial spaces, and the mesh having a mesh width and a mesh thickness, wherein the mesh is configured to receive a sample material and retain a portion of the sample material within the interstitial spaces of the mesh to form a sample having a sample thickness which is substantially the same as the mesh thickness. The mesh width may be sized to be in a range of about 1 to 3 times the width of an infrared beam directed toward the sampling tool from the spectrophotometer.

A cuvette with at least one side having materials with thermal conductivity of at least 5 W/m-K, such as sapphire, for holding contact lenses or intra-ocular lenses during optical measurements. The cuvette may further include a backstop to ensure consistent measurements and a pedestal to minimize optical measurement variations.