G01N2021/0346

Fluid detection panel with filter structure and fluid detection device with filter structure

A fluid detection panel and a fluid detection device are disclosed. The fluid detection panel includes a fluid-driven substrate, a filter structure and a sensor. The filter structure is configured to filter light emitted by a light source; the fluid-driven substrate comprises a detection area, and is configured to enable a liquid sample to move to the detection area; the sensor is configured to receive light which is emitted by the light source and sequentially passes the filter structure and the detection area.

Color dispersion apparatus and spectrometer

The present disclosure relates to a dispersion apparatus. The dispersion apparatus may include an optical substrate; a grating layer on a first side of the optical substrate; and a light outlet layer on a second side of the optical substrate, the second side opposite the first side of the optical substrate. The grating layer is configured to perform dispersion of incident light into first-order diffracted beams having target wavelengths and transmit the first-order diffracted beams into the optical substrate, and wherein a diffraction angle of each of the first-order diffracted beams having the target wavelengths is smaller than a total reflection angle between the optical substrate and air. The light outlet layer is configured to extract the first-order diffracted beams having the target wavelengths in the optical substrate.

High-sensitivity terahertz micro-fluidic channel sensor and preparation method thereof

A high-sensitivity terahertz micro-fluidic channel sensor and a preparation method thereof. The sensor includes a substrate and a cover layer, respectively provided with a metal plane reflector and a metal microstructure layer; a micro-fluidic channel is formed between the metal plane reflector and the metal microstructure layer; and when the micro-fluidic channel tests liquid, a composite structure formed of the metal microstructure layer, the test liquid and the metal plane reflector shows good absorption properties. The method includes forming a metal plane reflector and a metal microstructure layer on a substrate and a cover layer, respectively; fixedly connecting the substrate to the cover layer, and forming a closed micro-fluidic channel between the substrate and the cover layer; and forming a through via, communicated to the micro-fluidic channel, on the substrate and/or the cover layer, to form a flow channel for transferring liquid to be tested to or from the sensor.

Methods and products for analyzing polymers
09745625 · 2017-08-29 · ·

Methods and products for analyzing polymers are provided. The methods include methods for determining various other structural properties of the polymers.

HIGH SENSITIVTY MEDICAL DEVICE AND MANUFACTURING THEREOF
20170242008 · 2017-08-24 · ·

This invention relates to a system and methods including their manufacturing technologies for enhanced sensing capability of one or more bioagents covering from HIV, Pathogens, virus, to cells detection. More particularly, this invention is related to HIV and pathogen diagnosis system and methods which may increase its sensitivity and may reduce the diagnosis time. Furthermore, the diagnosis system and method may be applicable to all early stage patients with various age groups, where early and accuracy in diagnosis, are required.

CENTRIFUGAL PLATFORM AND DEVICE FOR RAPID ANALYSIS OF OILFIELD FLUIDS
20170232435 · 2017-08-17 ·

A method of evaluating an asphaltene inhibitor includes providing a centrifugal microfluidic system including: a disc mounted to rotate about an axis; a microfluidic device mounted on the disc, the device having sample, solvent, inhibitor, and precipitant reservoirs and an analysis chamber in fluid communication with the sample, solvent, inhibitor, and precipitant reservoirs; and an optical detection system coupled to the analysis chamber and configured to measure the optical transmission of fluid in the analysis chamber. The method includes filling the sample, solvent, inhibitor, and precipitant reservoirs, respectively, with a sample, solvent, inhibitor, and precipitant; rotating the disc to generate centrifugal force to cause the sample, solvent, inhibitor, and precipitant to travel radially outward to the analysis chamber; and measuring the optical transmission of a mixture of the sample, solvent, inhibitor, and precipitant in the analysis chamber as a function of radial distance of the analysis chamber.

MULTI-CHANNEL DEVICE FOR CALCULATING COAGULATION CHARACTERISTICS OF A PATIENT'S LIQUID TEST SAMPLE AND METHODS OF USE RELATED THERETO
20220034914 · 2022-02-03 · ·

Devices and methods for calculating various coagulation characteristics associated with a patients liquid test sample. The presently disclosed and claimed inventive concept(s) relate to an improved device(s) and method(s) for conducting coagulation assays on a patients liquid test sample, including, without limitation, a patients whole blood sample.

MEASUREMENT OF LIQUID PARAMETERS USING A MICROFLUIDIC DEVICE

A microfluidic apparatus has a microchannel that includes at least one vertically oriented segment with a top section having a relatively wide opening and a bottom section having a relatively narrow opening. The top section is larger in volume relative to the bottom sections, and the middle sections taper down in at least one dimension from the top section to the bottom section. One or tens or hundreds of vertically-oriented segments may be provided, and they are fluidly coupled to each other. Each segment acts as a pressure-volume-temperature (PVT) cell, and the microchannel apparatus may be used to determine a parameter of a fluid containing hydrocarbons such as the dew point of the fluid or the liquid drop-out as a function of pressure.

Systems and methods for amplifying nucleic acids

An apparatus for performing a thermocyclic process, such as amplifying DNA, includes a microfluidic chip with a channel formed therein and one or more thermal distribution elements disposed over portions of the chip. Each thermal distribution element is configured to distribute thermal energy from an external thermal energy source substantially uniformly over the portion of the chip covered by the thermal distribution element. The portion of the chip covered by the thermal distribution element thereby comprises a discrete temperature zone. Other temperature zones can be defined by other thermal distribution elements or by portions of the chip not covered by a thermal distribution element. The channel is configured so that a fluid flowing through the channel would enter and exit the different temperature zones a plurality of times, thereby alternately exposing the fluid to the temperature of each zone for a period of time required for the fluid to traverse the zone.

Dynamic light scattering based microrheology of complex fluids with improved single-scattering mode detection

A fluid characterization measuring instrument is disclosed that comprises a sample vessel for a bulk complex sample fluid having a capacity that is substantially larger than a domain size of the complex sample fluid and that is sufficiently large to cause bulk scattering effects to substantially exceed surface effects for the complex fluid sample, a coherent light source positioned to illuminate the bulk complex sample fluid in the sample vessel and a first fibre having a first end positioned to receive backscattered light from the sample after it has interacted with the sample. The first fibre can also be positioned close enough to an optical axis of the coherent light source and to the sample vessel to substantially decrease a contribution of multiply scattered light in the backscattered light. The instrument can further comprise a first photon-counting detector positioned to receive the backscattered light from a second end of the fibre, correlation logic responsive to the first photon-counting detector and single-scattering fluid property analysis logic responsive to the correlation logic and operative to derive at least one fluid property for the sample fluid.