G01N2021/0357

Cover film for testing, testing member, and method of manufacturing cover film for testing

[Problems] Objects include providing a cover film for testing which can be well fixed to a substrate having a groove and in which a pressure sensitive adhesive does not invade into the groove, providing a testing member comprising the cover film for testing, and providing a method of manufacturing the cover film for testing. [Solution] The cover film for testing (1, 2) comprises a base material (10) and a pressure sensitive adhesive layer (20) laminated on one surface side of the base material (10). The cover film for testing (1, 2) has a region in which the pressure sensitive adhesive layer (20) does not exist in the plan view.

CHARACTERIZING PARTICLES VIA AN ANALYTICAL FLOW FIELD
20210102882 · 2021-04-08 · ·

The present disclosure describes a sample cell, method, and a computer implemented method of characterizing particles via an analytical flow field. In an exemplary embodiment, the sample cell includes (1) a sample cuvette including a top sample membrane, a sample container to contain a sample, and a bottom sample membrane, (2) a reference cuvette including a top reference membrane, a reference container to contain a solvent, and a bottom reference membrane, (3) where the sample cell is configured to allow a concentration boundary to form within the sample cell, and (4) where the sample cell is configured to allow the concentration boundary to move toward a bottom of the sample cell until equilibrium is reached in the sample cell.

Device and method for visualization of fluorophores

A device and method are described for the naked eye visualization of fluorophores. The device has a light source capable of exciting fluorophores, a rack to receive one or more fluorophores and a window through which test tubes can be observed. The method provides a means for inferring the conformational state of molecules from the amount of fluorescence emitted by the fluorophores.

DETECTION METHOD

A detection system including a detection device and an assay device. The detection device includes a space for receiving an assay device, a drive arrangement engaging the assay device to rotate the assay device, a light source arranged to direct light towards the assay device, and a diffuser arranged to diffuse light from the light source. The diffuser is arranged between the light source and the space. The detection device includes a light receiver arranged to receive light from the light source that has passed through the assay device.

Apparatus for optical inspection of small volumes of liquid sample and cuvettes therefor

A nephelometer that measures turbidity of low volume suspensions using measurements of light transmitted through and/or scattered by the sample. The sample suspension is placed in a tiered cuvette adapted to facilitate measuring the turbidity of low volume samples. The lower portion of the cuvette has smaller dimensions, in horizontal cross section, than the top portion. Both lower and upper portions have angled surfaces. The lower, smaller portion of the cuvette is interrogated by the nephelometer.

APPARATUS FOR ANALYSING A LIQUID SAMPLE COMPRISING PARTICLES
20210072148 · 2021-03-11 ·

An apparatus for analysing a liquid sample comprising particles, comprises: a first chamber (12) and a second chamber (14), and an optical path between the first chamber (12) and the second chamber (14), wherein: the first chamber (12) is a sample chamber comprising: a sample space for receiving the sample; a light input (24) for input of light into the first chamber (12) for interaction with the sample; and an exit aperture (26) arranged for scattered and/or reflected light to pass from the first chamber via the optical path to the second chamber (14); the second chamber (14) is a detection chamber comprising: an input aperture (28) for receiving light from the optical path; and a detector (25) for detecting, or a detector aperture for receiving, light to be detected; wherein the first chamber (12) and the second chamber (14) provide at least one light integrating volume, and wherein the first chamber (12) is configured such that in operation the liquid sample is present in the first chamber (12) and isolated from the second chamber (14).

INTEGRATED MULTIPLEXED PHOTOMETRIC MODULE AND METHOD

Reusable network of spatially-multiplexed microfluidic channels each including an inlet, an outlet, and a cuvette in-between. Individual channels may operationally share a main or common output channel defining the network output and optionally leading to a disposable storage volume. Alternatively, multiple channels are structured to individually lead to the storage volume. An individual cuvette is dimensioned to substantially prevent the formation of air-bubbles during the fluid sample flow through the cuvette and, therefore, to be fully filled and fully emptied. The overall channel network is configured to spatially lock the fluidic sample by pressing such sample with a second fluid against a closed to substantially immobilize it to prevent drifting due to the change in ambient conditions during the measurement. Thereafter, the fluidic sample is flushed through the now-opened valve with continually-applied pressure of the second fluid. System and method for photometric measurements of multiple fluid samples employing such network of channels.

Sample Cuvette
20200326272 · 2020-10-15 ·

A cuvette comprising a pyramidal shaped cavity with four sides surfaces, which are connected to each other by curves, wherein side surfaces and curves merge into a transition area that is located above a ring followed by a cone above the bottom of the pyramidally shaped cavity.

COVER FILM FOR TESTING, TESTING MEMBER, AND METHOD OF MANUFACTURING COVER FILM FOR TESTING
20200278287 · 2020-09-03 ·

[Problems] Objects include providing a cover film for testing which can be well fixed to a substrate having a groove and in which a pressure sensitive adhesive does not invade into the groove, providing a testing member comprising the cover film for testing, and providing a method of manufacturing the cover film for testing.

[Solution] The cover film for testing (1, 2) comprises a base material (10) and a pressure sensitive adhesive layer (20) laminated on one surface side of the base material (10). The cover film for testing (1, 2) has a region in which the pressure sensitive adhesive layer (20) does not exist in the plan view.

OPTICAL SENSOR FOR DETECTION OF FREE HEMOGLOBIN IN A WHOLE BLOOD SAMPLE
20200256845 · 2020-08-13 ·

Sensor for the optical detection of free hemoglobin (96) in a whole blood sample (99), the sensor comprising a translucent slab (2) with a front side (3) and a back side (4) facing away from the front side (3), wherein the front side (3) is adapted for being contacted with a whole blood sample (99); a reflective layer (5) at the front side (3) of the translucent slab (2), the reflective layer (5) being adapted to reflect light reaching the reflective layer (5) from the translucent slab (2); an optical probing device comprising a light source (10) and a detector (20), wherein the light source (10) is adapted to illuminate at least pores in the translucent slab, wherein the detector (20) is arranged to receive light (21) emerging from the pores (6) in response to an illumination (11) by the light source (10), and wherein the detector (20) is adapted to generate a signal representative of the detected light. The translucent slab (2) is provided with dead-end pores (6) extending from the front side (3) into the translucent slab (2) in a direction towards the backside (4). Each of the pores (6) has a respective opening (7) in the front side (3) of the translucent slab (2) penetrating the reflecting layer (5). A cross-sectional dimension of the openings (7) of the pores (6) is dimensioned so as to prevent red blood cells (98) from entering the pores (6), while allowing free hemoglobin (96) to enter the pores (6).