A calibration suspension unit has a container made of a flexible material that is filled with a calibration suspension for the calibration of a turbidity meter. There exists no air supernatant above the calibration suspension in the container. Further, a method for the manufacture of a calibration suspension unit is provided and its use for the calibration of a turbidity meter is described.

The disclosure relates to a method for making carrier for use in single molecule detection. The method includes: providing a rigid substrate; coating a polymer layer on a surface of the rigid substrate, the polymer layer is in semisolid state; transferring a nano-scaled pattern of a template on a surface of the polymer layer by pressing the template on the surface of the polymer layer; obtaining a flexible substrate by removing the template; and applying a metal layer on the flexible substrate. The carrier for use in single molecule detection has a relative higher SERS and can enhance the Raman scattering.

A method of spectroscopically assessing the chemical composition of a bubble while the bubble constrains a gas within the interior of the bubble by passing light passing through the bubble and comparing properties of the light before and after the light has passed through the bubble. The bubble is located, preferably compressed between a first plate and a second plate providing a compressed bubble with relatively flat first polar end wall portion adjacent the first plate in a relatively flat second polar end wall portion adjacent a second plate and directing the light to pass through the bubble via the first and second polar end wall portions.

An optical detection assembly for monitoring a fluid includes a light source, a light detector array, and a controller. The light source emits light into a fluid, while the light detector array includes a plurality of light detectors and receives light exiting the fluid. The controller determines the concentration of one or more substances in the fluid based on signals received from the light detector array. The assembly may include a second light detector array, with one array receiving transmitted light exiting the fluid, with the other receiving scattered light exiting the fluid. The assembly may include a vessel attachment receiving a portion of a vessel or a vessel connector connecting two vessels. The controller may be configured to determine the concentration of one or more substances in a fluid within a vessel received by a vessel attachment or in a fluid within a conduit defined by a vessel connector.

A process conducted in a rocking bioreactor is monitored using a flexible bag fitted with an in-situ probe. The probe includes a disposable bag insert or patch and a reusable probe module. The patch is secured to a wall of the bag, and the probe module is a detachable part that can be mated to the bag patch, then disassembled for future use, for example. The patch is secured to the bag, defining a sample gap, and the probe module is inserted or mated with the patch. The probe module includes one or more source elements and one or more detector element. Light is transmitted from the source elements, through the sample gap, to the detector element(s), which detect the light after interaction with contents of the bag.

Systems for an adjustable and flexible optic chamber system are disclosed herein. An exemplary device includes four adjustable side panels connected together so as to form an adjustable tubular rectangle surrounding an object being evaluated and an adjustable top panel comprising an optical lens that aligns with the object being evaluated when the adjustable top panel covers an opening of the tubular rectangle. Furthermore, the four adjustable side panels and the adjustable top panel form a flexible and adjustable optic chamber when joined together, the flexible and adjustable optic chamber being adjustable and flexible to conform to varied structures for the object being evaluated and eliminating external stimuli. The device may further include an electromagnetic wave source or mechanical wave source; and a computing device comprising a processor and memory, the processor executing instructions stored in the memory to receive a selection of a test from an application.

Described herein is a receptacle for holding a sample under spectrophotometer analysis comprising: a body, first and second opposing windows separated by a gap to provide a volume for a sample, wherein at least the first opposing window is supported by a first compliant member, and wherein under a force, the first compliant member allows positioning of the first opposing window relative to a first datum to set a desired: a) gap between the first and second opposing windows, and/or b) relative orientation of the first and second opposing windows.

An optical sensor device (1) for a fluid substance (LS) comprises a device body (2) having a detection portion (14), associated to which is a sensitive optical part that comprises at least one of an emitter (20) and a receiver (21) of an optical radiation (R.sub.e, R.sub.r). The detection portion (14) is made of a material transparent to the optical radiation (R.sub.e, R.sub.r) and has an inner surface (23a, 23b) and an outer surface (15), the outer surface (15) being designed to be in contact with the fluid substance (LS) and the inner surface (23a, 23b) being designed to be isolated from the fluid substance. The at least one of the emitter (20) and the receiver (21) of the sensitive optical part is optically coupled to the inner surface (23a, 23b) of the detection portion (14), in such a way that the optical radiation (R.sub.e, R.sub.r) is at least in part propagated through the detection portion (14), in particular with an angle and/or an intensity that is variable as a function of a characteristic of the fluid substance. The optical sensor device (1) comprises a protection arrangement, configured for preventing possible deformation of the detection portion (14) caused by an increase in volume of the fluid substance (LS), in particular deformation of at least one of its inner surface (23a, 23b) and its outer surface (15). The protection arrangement comprises at least one compensation element (13) having an elastically deformable body, which is able to contract, for compensating thereby a possible increase in volume of the fluid substance (LS) or else for enabling a reversible displacement of the detection portion (14) following upon a possible increase in volume of the fluid substance (LS).

A device for monitoring at least one parameter of a fluid specimen obtained from a patient. The device has a fluid conduit holder comprising a clamp configured to position a fluid conduit, which holds the fluid specimen obtained from the patient, in a position for optical analysis, and an optical analyzer having a light source and a light detector. The optical analyzer is configured to expose the fluid specimen contained within the fluid conduit to an illuminant and measure light received at the detector. The device has an optical alignment mechanism mechanically coupling the light source, the clamp, and the light detector together, and configured to align at least the light detector with the fluid conduit at the position for optical analysis.

Described herein is a receptacle for holding a sample under spectrophotometer analysis comprising: a body, first and second opposing windows separated by a gap to provide a volume for a sample, wherein at least the first opposing window is supported by a first compliant member, and wherein under a force, the first compliant member allows positioning of the first opposing window relative to a first datum to set a desired: a) gap between the first and second opposing windows, and/or b) relative orientation of the first and second opposing windows.