G01N2021/0364

DISTRIBUTED OPTICAL SENSING USING COMPRESSIVE SAMPLING

Distributed optical sensing systems utilize compressive sensing techniques to determine parameters sensed by a waveguide. The system generates light that is sent along a sensing waveguide, thereby producing backscattered light. A compressive sampling filter forms part of the system, and is used to selectively block portions of the generated light or the backscattered light. The backscattered light is received by a receiver and used to determine one or more parameters.

Apparatus and Method for Measuring Components in Fluidic Samples Sealed in a Bag
20180052101 · 2018-02-22 ·

The present invention discloses an apparatus and a method for measuring components in fluidic samples in a non-invasive fashion using Infrared (IR) transmission spectroscopy. Fluidic samples are sealed in flexible IR-transparent bags that are then fixed on a supporting bed. The supporting bed is then mounted between the front and back plates of the apparatus so that the bag is squeezed by two IR transparent windows from opposite directions until the windows contact the spacer sheet mounted on the back plate. The thickness of the spacer sets the gap distance between the two windows and thereby sets the optical path for the measurement in the transmissive mode.

PIPETTE TIP SYSTEM, DEVICE AND METHOD OF USE
20170197207 · 2017-07-13 · ·

This disclosure is directed to exemplary embodiments of systems, methods, techniques, processes, products and product components that can facilitate users making improved absorbance or fluorescence measurements in the field of spectroscopy with reduced (minimal) sample waste, and increased throughput, particularly in the study of biological sciences. A measuring system is provided having: a base unit with a means for locating a pipette tip; a pipette tip designed to interact with the base unit for purposes of accurate pipette tip positioning; at least one light supplying unit positioned to supply light to a liquid sample in the pipette tip and at least one light collecting unit positioned to collect light from a liquid sample in the pipette tip.

DEVICE AND METHOD FOR THE OPTICAL ASSESSMENT OF THE LEVEL OF HEMOLYSIS IN A BLOOD SAMPLE

A method for the optical evaluation of the level of hemolysis in a blood sample, said method comprising the steps of prearranging a device 100 comprising a light emitter, at least two photodetectors and a control unit arranged to operate the light emitter and to receive data by the photodetectors. The method then comprises a step of emitting, by the light emitter, of an inspection electromagnetic radiation towards the blood sample, said inspection electromagnetic radiation comprising a plurality of inspection electromagnetic waves having respective wavelengths .sub.E. A step follows of receiving, by the photodetectors, a return electromagnetic radiation coming from the blood sample, said return electromagnetic radiation comprising a plurality of return electromagnetic waves having respective wavelengths .sub.R.

Pipette tip system, device and method of use

This disclosure is directed to exemplary embodiments of systems, methods, techniques, processes, products and product components that can facilitate users making improved absorbance or fluorescence measurements in the field of spectroscopy with reduced (minimal) sample waste, and increased throughput, particularly in the study of biological sciences. A measuring system is provided having: a base unit with a means for locating a pipette tip; a pipette tip designed to interact with the base unit for purposes of accurate pipette tip positioning; at least one light supplying unit positioned to supply light to a liquid sample in the pipette tip and at least one light collecting unit positioned to collect light from a liquid sample in the pipette tip.

Gas Density Increase Measurement in a Film Chamber
20170108401 · 2017-04-20 ·

A method for a tightness test of a test piece (16) in a test chamber (10) whose wall is at least partly made of a flexible material, wherein said test piece is introduced into said test chamber and said test chamber is then evacuated, is characterized in that the tightness test is performed by measuring the gas density inside said test chamber (10) in the area outside said test piece (16).

DISPOSABLE LIQUID CHEMICAL SENSOR SYSTEM
20170108427 · 2017-04-20 ·

Embodiments as disclosed herein may provide a sensor system including a container, such as a bag, having a port assembly integrated therewith. The port assembly includes an optically transparent window and be configured such that a sensor may be mechanically attached to the port assembly to interface with the optical window. The sensor may include an index of refraction (IoR) sensor that measures the chemical concentration of a liquid inside the container based on a refractive index.

COMPONENT MEASUREMENT APPARATUS AND MEASUREMENT CHIP
20170102336 · 2017-04-13 ·

A blood glucose meter (component measurement apparatus) includes a measurement chip, and an apparatus main body including an insertion hole. The measurement chip includes a pair of plate pieces, a spacer arranged between the pair of plate pieces, and a cavity that can retain blood. A pair of wall portions of the insertion hole, facing each other at a measurement unit and in the vicinity of the measurement unit, is separated from each other with a width smaller than a thickness of the measurement chip in a lamination direction. The spacer elastically deforms by a state in which the pair of plate pieces is pressed by the pair of wall portions and defines a width of the cavity.

OPTICAL SENSORS FOR MONITORING BIOPHARMACEUTICAL SOLUTIONS IN SINGLE-USE CONTAINERS
20170097297 · 2017-04-06 ·

Disposable, pre-sterilized, and pre-calibrated, pre-validated sensor components are provided. The sensor components interact with a sensor system having disposable fluid conduit or bioreactor bag and a reusable sensor assembly. The components can include an optical bench or inset optical component or module designed to be integrated within the disposable fluid conduit or bioreactor bag, which provides an optical light path through the conduit or bag. The sensors systems are designed to store sensor-specific information, such as calibration and production information, in a non-volatile memory chip on the disposable fluid conduit or bag and on the reusable sensor assembly. Methods for calibrating the sensor and for determining a target property of an unknown fluid are also disclosed. The devices, systems and methods relating to the sensor are suitable for and can be outfitted for turbidity sensing.

Apparatus and method for performing a light-absorption measurement of a specified amount of sample subject to pressure force

An apparatus and a method are disclosed for performing a light-absorption measurement of a specified amount of sample. A method for performing a light-absorption measurement of a specified amount of sample includes placing the sample on the surface of an apparatus including the surface and a light reflector, the light reflector being mechanically coupled with the surface and separated from the surface by a separation distance, changing the separation distance, while the light reflector remains mechanically coupled with the surface, to a first separation distance, and performing a first light-absorption measurement of the sample via the apparatus, while the separation distance is equal to the first separation distance, and while the sample is subject to pressure force.