The present disclosure provides methods and systems for performing single-molecule detection using fabricated integrated on-chip devices. In an aspect, the present disclosure provides a method for on-chip detection of an array of biological, chemical, or physical entities, comprising: (a) providing an array of light sensing devices; (b) immobilizing the array of biological, chemical, or physical entities on a substrate of the array of light sensing devices; (c) exposing the array of biological, chemical, or physical entities to electromagnetic radiation sufficient to excite the array of biological, chemical, or physical entities, thereby producing an emission signal of the array of biological, chemical, or physical entities; (d) using the array of light sensing devices, acquiring pixel information of the emission signal of the array of biological, chemical, or physical entities without scanning the array of light sensing devices across the array of biological, chemical, or physical entities; and (d) detecting the array of biological, chemical, or physical entities based at least in part on the acquired pixel information.

A high-altitude atmospheric sensor may include a frame configured to attach to a body of an aircraft, where the frame defines an open measurement cavity for air to travel through during flight of the aircraft. The sensor may further include one or more light sources providing input light such as mid-infrared quantum cascade lasers, a beamsplitter to separate the input light into measurement light propagating along a measurement path and reference light propagating along a reference path, one or more measurement cells providing optical paths for the measurement light in the open measurement cavity of the frame, one or more detectors to capture the measurement light from the one or more measurement cells and the reference light, and a controller to generate one or more spectroscopy measurements of air passing through the open measurement cavity during the flight of the aircraft.

Techniques are disclosed for a chemical sensor architecture based on a fabric-based spectrometer. An example apparatus implementing the techniques includes a portable spectrometer device including a first fabric layer and a second fabric layer coupled to the first fabric layer to form a pouch. The second fabric layer includes a fiber fabric spectrometer substrate comprising a fiber material including one or more electronic devices, wherein the pouch is configured to receive a colorimetric substrate and the fiber fabric spectrometer substrate is configured to measure reflectance of a colorimetric substrate disposed in the pouch.

An imaging system connected to an occupant monitoring system includes communications with an apparatus for measuring gas or airborne compound concentrations in a vehicle cabin. The apparatus includes a housing configured as a flow tube in fluid communication with ambient air in the vehicle cabin. A spectrometer is mounted within the housing and subject to ambient air flow through the housing, and the spectrometer is connected to a light source and receives reflected light from the air flow to detect by spectrum analysis the concentration of target gases and/or airborne compounds. The spectrometer identifies spectral changes in the light and reflected light within the ambient air flow. The spectrometer communicates with computerized vehicle control systems, and runs software stored to calculate the concentration of target gases and/or airborne compounds from the spectral changes.

When a measurement sample whose absorbance greatly changes depending on a wavelength range is measured, measurement with a high S/N ratio and accuracy can be efficiently performed in a short time.

For a plurality of wavelength ranges in wavelength scanning measurement of a measurement sample, based on measurement conditions including one of a plurality of dimming plates (16a to 16e) to be disposed in each wavelength range and a scanning speed of a wavelength to be set in each wavelength range, when wavelength scanning measurement in which the entire measurement wavelength range including all of the plurality of wavelength ranges is scanned at once is performed, a spectrophotometer (100) changes one of the plurality of dimming plates (16a to 16e) and the scanning speed according to the measurement conditions for each wavelength range.

An optical sensor system may include a light source. The optical sensor system may include a concentrator component proximate to the light source and configured to concentrate light from the light source with respect to a measurement target. The optical sensor system may include a collection component that includes an array of at least two components configured to receive light reflected or transmitted from the measurement target. The optical sensor system may include may a sensor. The optical sensor system may include a filter provided between the collection component and the sensor.

A device comprising: an optical emitter for emitting light having an emitted optical spectrum; an optical sensor for receiving light reflected from a tag attached to an object; and a processor configured to: determine a reflected optical colour spectrum of the light reflected from the tag based on an output of the optical sensor; retrieve an optical signature associated with said object from memory; and determine the authenticity of said object based on comparing the optical signature and the reflected optical colour spectrum.

The present disclosure relates to a spectrometer comprising a spectral decomposition device and a radiation detector. These components are configured such that the spectral decomposition device can break up an incident electromagnetic measuring radiation into components in a wavelength-dependent manner. The radiation detector can measure the intensity of at least one of these components. The spectrometer is configured such that the spectrometer transmits analysis information from the analysis of a food or of a food component to a food preparation device and/or outputs it to the user via an output device. The present disclosure further relates to a system including a control device as well as to a method. In this way, a reproducible cooking result as well as an output of the nutritional values and the actual energy content of the prepared food can be made possible.

Aspects relate to mechanisms for mass screening of samples. A portable laboratory device based on spectroscopic analysis of samples containing analytes under test can facilitate the mass screening. The portable laboratory device can include a sample head including a structure configured to facilitate application of the sample to the sample head and an optical measurement device including one or more light sources and a spectrometer. Light from the light source(s) incident on the sample may be directed to the spectrometer to obtain a spectrum of the sample. The optical measurement device can further include a data transfer device configured to provide the spectrum obtained by the spectrometer to a spectrum analyzer to produce a result from the spectrum.

The invention relates to a device for a light-spectroscopic analysis of a, for example, liquid sample. In particular, light should be guided through a sample and then detected and/or analyzed photometrically, spectrophotometrically, fluorometrically, spectrofluorometrically and/or by means of phosphorescence or luminescence.