A reagent test paddle includes a contamination detection medium, a reference color bar, at least one chemical test medium, and a unique identifier. The contamination detection medium includes a reagent that changes color in the presence or when exposed to a hostile or inhospitable environment. Each chemical test medium includes a regent that is responsive to a respective analyte in a biological sample. The reference color bar includes reference color samples of different colors. The unique identifier, like a serial number, identifies the particular paddle and its chemical test medium so it can be uniquely and anonymously associated with a user. A method includes capturing and interpreting digital images of a biologically unexposed and subsequently exposed reagent test paddle at various delay times within an automatically calibrated environment; locating the paddle in a plurality of digital images, extracting the reference color bar and locating the contamination detection medium and chemical test medium in each digital image. Color changes of the chemical test medium and contamination medium are detected at various delay times after sample exposure. To determine validity of test results, the method further compares the detected colors of the contamination detection medium with predetermined colors expected for no contamination and contamination.

A method of performing an analytical measurement includes using a camera of a mobile device to capture a time series of images of at least a part of a medical article. From this, image-derived position information on a relative position of the mobile device and the medical article is derived, thereby generating a first time series of position information. A sensor captures measurement information on the relative position of the mobile device and the medical article. Measurement-derived position information is used to generate a second time series of position information, and the first and second time series of position information are combined to generate an augmented time series of position information. From this, guidance is provided to a user to move the mobile device and the medical article into a relative target position. A mobile device, a kit and a computer program are also disclosed.

A gas sampling apparatus having a sampling film in a cartridge includes the cartridge configured to store and send the sampling film out, and the sampling film detachable from the cartridge, wherein the sampling film is configured to adsorb a target material and prevent disturbance between sampled target materials.

A reagent test paddle includes a contamination detection medium, a reference color bar, at least one chemical test medium, and a unique identifier. The contamination detection medium includes a reagent that changes color in the presence or when exposed to a hostile or inhospitable environment. Each chemical test medium includes a regent that is responsive to a respective analyte in a biological sample. The reference color bar includes reference color samples of different colors. The unique identifier, like a serial number, identifies the particular paddle and its chemical test medium so it can be uniquely and anonymously associated with a user. A method includes capturing and interpreting digital images of a biologically unexposed and subsequently exposed reagent test paddle at various delay times within an automatically calibrated environment; locating the paddle in a plurality of digital images, extracting the reference color bar and locating the contamination detection medium and chemical test medium in each digital image. Color changes of the chemical test medium and contamination medium are detected at various delay times after sample exposure. To determine validity of test results, the method further compares the detected colors of the contamination detection medium with predetermined colors expected for no contamination and contamination.

A method of determining concentration of an analyte in a body fluid using a mobile device having a camera is disclosed. In the inventive method, the camera is used to take a series of calibration images of a region of interest of an object. The calibration images differ in their brightness. A key calibration figure is derived from each calibration image, the key calibration images being characteristic for a tone mapping function of the mobile device. A probable tone mapping function of the mobile device is determined by taking into account the key calibration figures. An analysis image is taken of at least part of a test field of an optical test strip, the test field having a body fluid applied thereto. Analyte concentration is determined from the analysis image of the test field by taking into account the probable tone mapping function of the mobile device.

The present disclosure relates to using color calibration to improve and increase the accuracy of interpreting color-sensitive results from test strips made of substrates like paper. This is accomplished via a diagnostic test unit including a substrate, at least one region on the substrate, a reagent placed within the region to react, and a series of color legends on the substrate. Different reagent samples may be placed on the separate regions of a substrate for testing. An imaging device is used to capture the reaction results. More precise readings can be obtained by comparing the reaction results to the color legends to determine the measured property of the analyte.

Techniques for colorimetric based test strip analysis and reader system are provided. In one aspect, a method of test strip analysis includes: illuminating a test strip wetted with a sample with select spectrums of light, wherein the test strip includes test pads that are configured to change color in the presence of an analyte in the sample; obtaining at least one digital image of the test strip; and analyzing color intensity from the at least one digital image against calibration curves to determine an analyte concentration in the sample with correction for one or more interference substances in the sample that affect the color intensity. A calibration method and a reader device are also provided.

A method for analyzing a diagnostic test may include receiving an image depicting a diagnostic test, wherein the diagnostic test comprises a test region indicating a test result, validating quality of the image, locating a test region image portion of the image depicting the test region of the diagnostic test; and predicting the test result based on the test region image portion. Furthermore, a method for facilitating analysis of a diagnostic test may include receiving one or more images depicting one or more control markings on a scan surface, wherein the one or more control markings are representative of one or more predetermined test results for the diagnostic test, and verifying detection of the one or more control markings in the one or more images using at least one computer vision technique.

A lateral flow assay device includes several markers, a color bar, and/or a grayscale on the housing of the lateral flow assay device. The markers are used to assist in focusing a mobile device's camera on the control line of the lateral flow assay device. The markers may be used to adjust the perspective of an image taken from the control line and the test line of the lateral flow assay device. The markers may be used to locate the images of the control line, the test line, the color bar, and/or the grayscale on the image. The image of the color bar and the grayscale may be used to adjust the colors and intensity of the image. The images of the test line and the control line may then be used to determine the test results of the lateral flow assay device.

Disclosed is a device including at least a section 1, a section 2, a section 3 and a section 4 wherein section 2 is coupled to section 1, section 3 is coupled to section 2 and comprises a surface functionalized with an analyte or equivalent thereof, section 4 is coupled to section 3, and section 1, section 2, section 3 and section 4 are arranged along a horizontal axis and in fluid communication allowing lateral flow from section 1 throughout all sections to section 4. Disclosed are also a kit and method for determining and quantifying the presence of an analyte in a sample.