A gas sampler (30) is provided with a connection portion (C1) connectable to a sample tank (20), a sample loop (PL) for holding a sample gas introduced from the sample tank (20) to the connection portion (C1), pneumatic switching valves (V1 to V6) for switching a flow path connected to the sample loop (PL), a control piping (81) for transmitting a driving pressure to the switching valves (V1 to V6), a pump (31) for suctioning an inside of the sample loop (PL), and a pressure accumulation tank (80) for accumulating the pressure generated by the operation of the pump (31) as a source pressure.

Methods and devices to capture and analyze aerosolized particles such as protein biomarkers and their truncated proteoforms characteristic of a disease, including a respiratory disease, in exhaled breath to enable rapid detection of diseases are disclosed. The disclosed methods and systems selectively capture aerosolized particles using a packed bed column. The captured particles are then eluted using one or more solvents and analyzed using devices including mass spectrometry.

A method for synchronizing data for gas samples with volatile organic compounds. The data includes chromatographic data indicative of molecule retention times. The method includes identifying or selecting marker molecules and clustering the plurality of gas samples into a plurality of clusters according to a clustering criterion. Next, a first correction of retention time deviations is performed on the data for the gas samples between clusters by using the marker molecules as anchor points to provide a coarse reduction of retention time deviations between the data. Finally, a second correction of retention time deviations is performed on the data, so as to further reduce retention time deviations between the data. The method reduces significant retention time deviations to allow, e.g., breath sample fingerprints obtained by different equipment at different times to be compared in one database for use on a digital platform.

Techniques and apparatus for executing jobs for performing analytical methods are described. In one embodiment, for example, an apparatus may include at least one memory, and logic coupled to the at least one memory. The logic may be configured to receive a job request from a data system to perform a job, and determine an acquisition system to perform the job, the acquisition system to determine at least one task for the job, provide the at least one task to a task sequencer to coordinate performance of the at least one task, and provide data artifacts to the data system resulting from performance of the at least one task. Other embodiments are described.

A process and system for monitoring and controlling the operation of a dehydrogenation reactor is provided. Samples of hydrocarbon streams are taken at sampling locations to be analyzed at a single gas chromatograph or other analytical equipment. Actions can be taken to modify the operation of the dehydrogenation reactor as necessary to maintain its operation within predetermined parameters. In particular, actions may be taken when a hydrocarbon stream exhibits an amount of cracking that is outside parameters. It is usually intended that actions will be taken on a gradual basis once or twice per day to reduce the cost of the process while still providing the necessary changes to operations.

A portable gas analysis device having a separating column and a detector. The separating column is composed as a multi-capillary unit from parallel individual capillaries and, depending on the length, is bent into a compact shape, preferably even wound into multiple turns. A thermally conductive casing and a thermal stabilizing device are provided for the multi-capillary unit. The thermal stabilizing device comprises a temperature sensor, a heating element and control electronics. The casing protects the sensitive multi-capillary unit from mechanical actions; it acts as a protective space. The temperature-controlled casing also forms a space in which uniform and controlled conditions prevail and which in particular is isolated from the temperature and humidity of the environment, allowing reliable measurements outside a laboratory environment, in the field. This double effect of the casing for the capillaries in conjunction with the compact dimensions forms the true essence of the invention.

Methods for classification of hydrocarbon mixtures that include performing two-dimensional gas chromatography on a hydrocarbon mixture to obtain a chromatogram using a two-dimensional gas chromatograph equipped with a flame ionization detector, a reversed phase column configuration with a primary mid-polar or polar column and a secondary non-polar column, and a standard mixture. Classification is performed in which groups of hydrocarbons are identified and labeled based on peaks associated with the standard mixture, after which a quantification process is performed.

Micro gas chromatographic devices are provided having a microfluidic separation column and a plurality of capillaries where the capillaries have been independently configured in terms of the capillary length, capillary width, the packing density and packing geometry of the capillary using one or more micro pillars, the tortuosity of the capillary path, and the presence and identity of the stationary phase for use in micro gas chromatographic separation of complex mixtures of compounds. Through the plurality of capillaries, the devices are capable of discriminating between complex samples even in instances where complete separation of the components is not possible. Methods of fabrication and methods of use of the devices are also provided. The devices can be readily fabricated using known techniques. The devices can be used for the analysis of complex mixtures of compounds containing tens or hundreds of compounds in which just a few differ in presence or concentration.

In a quantitative determination device 10 for brominated flame-retardant compounds, a storage section 41 holds a relative response factor 411 representing a relationship of a measured intensity of a compared compound to that of a reference compound selected from target compounds. A standard-sample measurer 43 acquires the intensity of the reference compound by measuring a standard sample, using an analyzer 10, 20. A target-sample measurer 45 acquires the intensities of the reference and compared compounds by measuring a target sample, using the analyzer. A reference-compound quantity determiner 46 determines a quantitative value of the reference compound in the target sample. A compared-compound quantity determiner 47 determines a quantitative value of the compared compound based on the quantity of the reference compound in the standard sample, intensity of the reference compound acquired by the standard-sample measurer, intensity of the compared compound acquired by the target-sample measurer, and relative response factor of the compared compound.

A flame photometric detector for a process gas chromatograph is provided. The flame photometric detector includes a combustion chamber body defining a combustion chamber therein. A sample inlet tube is configured to introduce a process gas sample into the combustion chamber. An ignitor is configured to initiate combustion within the combustion chamber. A thermocouple assembly is configured to provide an indication of temperature within the combustion chamber. The sample tube has an end that is adjustable relative to the combustion chamber.