A sample injection device is used to inject a sample into a chromatograph and includes a flow vial, a sampling needle and one or more than one sample dissolution devices. A sample is supplied to the flow vial. The sample that has been supplied to the flow vial is collected by the sampling needle and injected into the chromatograph. At least one of ultrasonic waves, an electric field and a magnetic field is used, so that dissolution of a sample to be injected into the chromatograph is promoted by one or more than one sample dissolution devices.

A container assembly for use with a high-pressure liquid chromatography (HPLC) instrument is disclosed, in which the container assembly, when coupled to a source of pressurized gas, provides fluid medium to the HPLC instrument at positive pressure. The container assembly has an external exterior container shell, an internal fluid container for holding fluid medium, an interstitial volume between the external exterior container shell and the internal fluid container, a port for fluidly connecting the volume to a pressurized gas source, and a port for fluidly connecting the internal fluid container to the HPLC instrument. As a pressurized gas in the interstitial volume increases, fluid medium flows out of the port connected to the internal fluid bag and container assembly at a positive pressure. A system incorporating the container assembly, and method of use of the same, are also disclosed.

A container assembly for use with a high-pressure liquid chromatography (HPLC) instrument is disclosed, in which the container assembly, when coupled to a source of pressurized gas, provides fluid medium to the HPLC instrument at positive pressure. The container assembly has an external exterior container shell, an internal fluid container for holding fluid medium, an interstitial volume between the external exterior container shell and the internal fluid container, a port for fluidly connecting the volume to a pressurized gas source, and a port for fluidly connecting the internal fluid container to the HPLC instrument. As a pressurized gas in the interstitial volume increases, fluid medium flows out of the port connected to the internal fluid bag and container assembly at a positive pressure. A system incorporating the container assembly, and method of use of the same, are also disclosed.

A process which, on the basis of a provided test sample including a mix of a plurality of preknown sample components and on the basis of provided absolute sample separation properties for each of the sample components, includes experimentally determining a real sample separation result by executing a sample separation method for separating the test sample by a sample separation apparatus, and determining a real value of at least one operation parameter based on a comparison between the absolute sample separation properties and the real sample separation result for characterizing a real course of the sample separation method.

A process which, on the basis of a provided test sample including a mix of a plurality of preknown sample components and on the basis of provided absolute sample separation properties for each of the sample components, includes experimentally determining a real sample separation result by executing a sample separation method for separating the test sample by a sample separation apparatus, and determining a real value of at least one operation parameter based on a comparison between the absolute sample separation properties and the real sample separation result for characterizing a real course of the sample separation method.

A separation column (6), an injector (4) that injects a sample into a mobile phase flowing through a flow path (16) leading to the separation column (6), at least one detector (8;10) that is fluidly connected downstream of the separation column (6), and generates a plurality of detector signals different from each other derived from a component in a sample separated by the separation column (6), a fraction collector (12) for fractionating and collecting a portion containing a component separated by the separation column (6) in an eluate from the separation column (6) into an individual collection container, and a controller (14) that detects a component peak in a plurality of chromatograms based on each of a plurality of the detector signals and controls operation of the fraction collector (12) based on a result of the detection are included. The controller (14) includes a fractionating collection part (26) configured to execute fractionating collection in which a portion detected as a component peak only in one chromatogram of a plurality of the chromatograms and a portion detected as a component peak in all of a plurality of the chromatograms are collected separately in collection containers different from each other.

A separation column (6), an injector (4) that injects a sample into a mobile phase flowing through a flow path (16) leading to the separation column (6), at least one detector (8;10) that is fluidly connected downstream of the separation column (6), and generates a plurality of detector signals different from each other derived from a component in a sample separated by the separation column (6), a fraction collector (12) for fractionating and collecting a portion containing a component separated by the separation column (6) in an eluate from the separation column (6) into an individual collection container, and a controller (14) that detects a component peak in a plurality of chromatograms based on each of a plurality of the detector signals and controls operation of the fraction collector (12) based on a result of the detection are included. The controller (14) includes a fractionating collection part (26) configured to execute fractionating collection in which a portion detected as a component peak only in one chromatogram of a plurality of the chromatograms and a portion detected as a component peak in all of a plurality of the chromatograms are collected separately in collection containers different from each other.

There are provided a sample cooling device capable of preventing air containing moisture from flowing into an accommodating chamber from outside the accommodating chamber, and of desirably dehumidifying air inside the accommodating chamber, and an autosampler provided with the same. Air is sent into an accommodating chamber 11 by a blower section 100 from outside the accommodating chamber 11 and the air is cooled by a dehumidifier section 13 to thereby cause dehumidified air to be supplied into the accommodating chamber 11. With the air sent into the accommodating chamber 11 by the blower section 100 from outside the accommodating chamber 11, the inside of the accommodating chamber 11 may be placed in a pressurized state. Since dehumidified air is supplied into the accommodating chamber 11 by air sent into the accommodating chamber 11 by the blower section 100 from outside the accommodating chamber 11 being cooled by the dehumidifier section 13, the humidity inside the accommodating chamber 11 may be prevented from rising due to the air that is sent from the blower section 100.

There are provided a sample cooling device capable of preventing air containing moisture from flowing into an accommodating chamber from outside the accommodating chamber, and of desirably dehumidifying air inside the accommodating chamber, and an autosampler provided with the same. Air is sent into an accommodating chamber 11 by a blower section 100 from outside the accommodating chamber 11 and the air is cooled by a dehumidifier section 13 to thereby cause dehumidified air to be supplied into the accommodating chamber 11. With the air sent into the accommodating chamber 11 by the blower section 100 from outside the accommodating chamber 11, the inside of the accommodating chamber 11 may be placed in a pressurized state. Since dehumidified air is supplied into the accommodating chamber 11 by air sent into the accommodating chamber 11 by the blower section 100 from outside the accommodating chamber 11 being cooled by the dehumidifier section 13, the humidity inside the accommodating chamber 11 may be prevented from rising due to the air that is sent from the blower section 100.

A device for analyzing a gaseous sample including a first housing including a detection assembly housed in the housing including a preconcentrator, a chromatography column and a detector intended to detect the presence of the separated compounds, a sampling assembly including a cartridge that is removable relative to the first housing, a control and processing unit housed in the housing and configured to execute an analysis operating mode capable of generating a first command for the detection assembly to analyze a first gaseous sample, a second command to determine the exceeding of at least one alert threshold and, if an alert threshold is exceeded, a third command for the sampling assembly to take a second gaseous sample.