The present invention provides a processing device with a high degree of flexibility in setting of preprocessing and which is capable of increasing the preprocessing efficiency, and an analysis system provided with the same. Setting receiving means (84d) receives, for each sample, setting of a plurality of types of preprocessing and a parameter for each preprocessing. A preprocessing execution section (84e) controls a plurality of preprocessing sections and a transport arm (24) so that a plurality of types of preprocessing set for each of different samples is performed simultaneously in parallel. The preprocessing execution section (84e) performs control in such a way that preprocessing is not to be performed on different samples at the same preprocessing section at the same.

The present invention provides a preprocessing device of a more compact structure, and an analysis system provided with the same. A preprocessing device (1) includes a container holding section (12), a filtration port (30), and a transport arm (24). The container holding section (12) holds a separation container (50) and a collection container (54). The filtration port (30) separates a sample by applying pressure to a sample in the separation container (50). The transport arm (24) transports the separation container (50) and the collection container (54) held by the container holding section (12) from a predetermined transport position. The container holding section (12) holds the separation container (50) and the collection container (54) in an annular or arch-shaped holding region formed on an outer circumference of the filtration port (30), and sequentially moves the separation container (50) and the collection container (54) to the transport position by shifting the separation container (50) and the collection container (54) in the circumferential direction of the holding region.

Provided is an analytical measurement device system 10 having a plurality of units (liquid-sending pump 12; detector 15) including: a sensor (flow sensor 121; light amount detector 151) provided in at least one unit among the plurality of units, for detecting the condition of a specific portion of the unit; a determination section (flow rate determiner 122; light amount determiner 152) provided in the unit, for receiving a signal from the sensor and for determining an overall condition of the unit based on a predetermined determination criterion; a storage section (flow-rate determination information storage section 123; light-amount determination information section 153) provided in the unit, for storing the determination criterion and a result of the determination by the determination section; and a display section (flow-rate determination result display section 124; light-amount determination result display section 154) provided in the unit, for displaying the determination result.

A sensor structure is disclosed comprising at least four planar layers subsuming at least one cavity housed but not contained by overlapping apertures through at least two of the planar layers, wherein the at least one cavity comprises a plurality of chambers, and wherein at least one chamber of the plurality of chambers is configured to be in fluid coupling with at least one other chamber. The plurality of chambers may be defined by overlapping apertures through a plurality of the planar layers. The plurality of chambers may include a Gas Chromatograph (GC) column. The planar layers may be flexible flat glass. The planar layers may be fused together. The layers may be made with apertures through the layers disposed in a desired pattern to define complex structures by the apertures overlapping between abutting layers when the layers are stacked. The planar layers may be configured to admit ultraviolet light.

A pre-analysis treatment device usable for an amino acid, organic acid, and glucide includes an ion-exchange unit configured to load a test sample on a solid-phase cartridge S having a strong ion-exchange resin phase, to allow the strong ion-exchange resin phase to adsorb a predetermined organic compound, then supply a dehydration solvent to dehydrate the strong ion-exchange resin phase, and a derivatization unit configured to feed a predetermined amount of the derivatization reagent to the dehydrated strong ion-exchange resin phase to allow the derivatization reagent to retain for a predetermined time period, thereby trimethylsilylating the organic compound adsorbed on the strong ion-exchange resin phase, and simultaneously desorbing the trimethylsilylated organic compound from the strong ion-exchange resin phase, and then supply a push-out solvent to push the trimethylsilylated organic compound desorbed, out of the solid-phase cartridge S. The device enables at least one organic compound selected from amino acids, organic acids and glucides contained in a test sample to be derivatized and collected easily in a short period of time, and automation of the pre-analysis treatment.

At least one of method information representing an analysis execution method to be used for analysis of a sample and device information for specifying the configuration of an analysis device is acquired as analysis information by an analysis information acquirer. Syringe information for specifying the configuration of a syringe is acquired by a syringe information acquirer. Based on the analysis information and the syringe information, whether the syringe is suitable for analysis of the sample is judged by a judge. The result of judgement by the judge is presented by a presenter.

A transfer system (1) is a transfer system (1) that transfers a sample container (S) containing a sample from a transfer source device (100) to a transfer destination device (200) disposed adjacent to the transfer source device (100), and the transfer system (1) includes an arm (2) having a distal end and a proximal end, the distal end portion facing the transfer destination device (200), and a first catcher (4) for detachably holding the sample container (S) at the distal end, a drive mechanism (14) provided in the transfer source device (100) and configured to drive the arm (2) to move the first catcher (4) between a first position in the transfer source device (100) and a second position in the transfer destination device (200), and a second catcher (16) provided in the transfer destination device (200) and provided so that the sample container (S) is delivered and received between the first catcher (4) and the second catcher (16) when the first catcher (4) reaches the second position.

An autosampler includes: a sample cooling unit that is brought into thermally contact with a bottom surface of a sample rack so as to cool a sample accommodated in the sample rack; a condensed water receiver that has at least one hole on a bottom surface thereof, and is provided below the sample rack for receiving water condensed around the sample rack; a discharging passage configured in such a manner that a droplet falling from the at least one hole flows therein.

A method for characterizing a target peptide through a detection approach such as mass spectrometry is provided, including: introducing at least one guard molecule to mix with the target peptide; and applying the detection approach for the characterization of the target peptide. Each guard molecule is configured to have similar characteristics as the target peptide, yet is still distinguishable therefrom by the detection approach, such as having a mass spectrometry-distinguishable different M/z value compared with the target peptide. The method can be used to characterize a neoantigen peptide through mass spectrometry, upstream of which the method can further include steps for tissue sample preparation, HLA molecules enrichment, elution, clean-up, and purification. Some or all of these steps can be configured to be executed in a substantially automatic manner with little or no manual intervention. A system for implementing the neoantigen analysis method is further provided.

A range of pH of a mobile phase that is usable for an analysis with use of each column is registered by a pH range registrar in association with identification information of each column. A pH of each mobile phase is registered by a pH registrar. A column to be used for an analysis is selected by a column selector. A chromatograph is controlled by an analysis controller such that a mobile phase having a registered pH that is out of a range of pH that is registered in association with a selected column is not supplied to the selected column. The chromatograph is controlled by the analysis controller such that an analysis is performed while a mobile phase having a registered pH that is in a range of pH that is registered in association with a selected column is supplied to the selected column.