G01N2035/00108

SUBSTRATE READER AND METHOD OF READING A SUBSTRATE

A device including a light source, one or more actuators, and an image capturing device. The device is operable to receive a request to capture image data of a sample, determine at least one of an analyte being tested within the sample or a container holding the sample, position the image capturing device relative to the sample based on the analyte being tested or the container holding the sample, illuminate the light source based on the analyte being tested or the container holding the sample, capture the image data, and send the image data to one or more computing devices for image processing.

Optical assay device with pneumatic sample actuation

This invention relates generally to devices and methods for performing optical and electrochemical assays and, more particularly, to test devices, e.g., cartridges, methods and systems, wherein the test devices have an entry port configured to receive a test sample into a holding chamber; a first conduit having at least one lateral flow test strip; and a displacement device, such as a pneumatic pump, configured to move a portion of said test sample from said holding chamber into said first conduit. The present invention is particularly useful for performing immunoassays and/or electrochemical assays at the point-of-care.

A DOSING MODULE
20200371003 · 2020-11-26 ·

A dosing module (137) in an agricultural environment, arranged to apply a milk sample of an animal (100) onto a dry stick (180a, 180b, 180c). The dosing module (137) includes a milk insertion connection (340) arranged to receive milk; a needle (350) configured to receive the milk and apply the received milk to the dry stick (180a, 180b, 180c); a first pump (611), configured to provide milk from the milk insertion connection (340) to the needle (350); and a position adjustment mechanism (510) configured to adjust the needle (350) between a retracted position () above the dry stick (180a, 180b, 180c) when dosing milk to the dry stick (180a, 180b, 180c), and at an extended position () when flushing milk through the needle (350); and an evacuator (195) arranged to intercept liquid output by the needle (350).

Lateral flow immunoassay test reader and method of use

A reader for a lateral flow test device includes a tray or drawer, extendable from the reader, which receives the test device. The tray includes a calibration test pattern affixed or printed thereon placed proximate to the test device and in alignment with the axis of the test device. As the tray is closed and the test device is inserted to the reader, the calibration test pattern is first read by an optics unit including a photodiode. The resulting photodiode output provides a calibration curve S that the reader then uses to correct for any non-linear response of the reader's optical or electronic systems, thus insuring that every reader will yield the same readout for a given test cartridge, despite reader-to-reader variations or reader degradation with time. One use of the reader is for detection of SARS-CoV-2 infection.

FULL-AUTOMATIC EXCREMENT ANALYZER
20200341018 · 2020-10-29 ·

The present invention provides a full-automatic feces analyzer, comprising an automatic controller; at least one sample box for containing a feces sample; a sample box support for placing the sample box; a dilution and stirring unit for adding diluent into the feces sample in the sample box and performing stirring to obtain feces sample liquid; a physical detection unit for performing a physical detection on the feces sample liquid; at least one chemical detection unit for performing a chemical detection on the feces sample liquid, each chemical detection unit comprising a driving roller and a driven roller, a reagent strip roll being wound on the driven roller, an end portion of the reagent strip roll being fixed on the driving roller, and the reagent strip roll comprising a plurality of reagent strips which are abreast distributed and sequentially connected; and a sample sucking and adding unit for sucking the feces sample liquid and delivering the feces sample liquid to the physical detection unit and the chemical detection unit. The full-automatic feces analyzer can perform continuous physical detections and chemical detections to a plurality of feces samples, and the detection efficiency thereof is very high.

Method and apparatus for coding diagnostic meters

A system for diagnostic testing may include a meter for performing a diagnostic test on a sample applied to a test media, the meter having a housing and an interface for receiving a signal representing coding information, and a container configured to contain test media compatible with the meter, the container having a coding element associated therewith. Additionally, the system may provide a mechanism for removing the meter from an interconnected test container and reattaching it to a new container using on-container coding methods that can recalibrate the meter for the new container of test strips.

Test element analysis system for the analytical examination of a sample

A test element analysis system for the analytical examination of a sample comprising: at least one evaluation device with at least one test element holder and at least one measuring device for measuring a change in a measuring zone of a test element; at least one barcode reader comprising at least one circuit board having a front side facing the barcode of the test element positioned in the test element holder and a reverse side facing away from the test element, wherein at least one electronic control element of the barcode reader is disposed on the circuit board and wherein the circuit board comprises at least one cavity penetrating the circuit board; at least one camera carrier element; and at least one camera electrically connected to the camera carrier element, with the camera carrier element and the camera being positioned such that the camera observes the barcode through the cavity.

Methods and systems for epi-fluorescent monitoring and scanning for microfluidic assays

A method and system for heating and/or inspecting a portable microfluidic assay cartridge for performing an assay includes receiving the assay cartridge on a receiving region of a translatable table under automated control, heating the cartridge, during performance of the assay, with a planar radiant heater plate, the heater plate having an aperture through which an inspection axis extends, and/or inspecting the cartridge using an optical system constructed to inspect the cartridge along the inspection axis by reading a fluorescent light signal which passes through the aperture in the heater plate. In addition, the cartridge moves with movement of the translation table, and the heater plate and optical system may be stationary, and the inspection axis may be fixed.

Assay test strips with multiple labels and reading same

In one aspect, an assay test strip includes a test label that specifically binds a target analyte and a control label that is free of any specific binding affinity for the target analyte and has a different optical characteristic than the test label. In another aspect, an assay test strip includes a test label that specifically binds a target analyte and at least one non-specific-binding label that is free of any specific binding affinity for the target analyte. Systems and methods of reading assay test strips also are described.

Biosensor for determining a concentration of a biosensor using an underfill procedure

A biosensor has an underfill detection system that determines whether a sample of a biological fluid is large enough for an analysis of one or more analytes. The underfill detection system applies an excitation signal to the sample, which generates an output signal in response to the excitation signal. The underfill detection system switches the amplitude of the excitation signal. The transition of the excitation signal to a different amplitude changes the output signal when the sample is not large enough for an accurate and/or precise analysis. The underfill detection system measures and compares the output signal with one or more underfill thresholds to determine whether an underfill condition exists.