G01N2035/00376

Automatic Analyzer

Provided is an automatic analyzer having a rapid start-up of a heat block while precisely controlling a temperature of a reaction solution. In the automatic analyzer equipped with a reaction-vessel-holding part, a heat block having a heat source to heat the reaction vessel, and a cooling system having a low temperature region and a high temperature region, an outer peripheral part of or below the reaction-vessel-holding part is defined as a heat transfer space, there are provided a heat transfer passage connecting the heat transfer space and the high temperature region, a heat medium circulating through the high temperature region, the heat transfer passage, and the heat transfer space, and a flow rate control means configured to control a flow rate of the heat medium in the heat transfer passage, and a temperature detection means is provided on a downstream side of the high temperature region.

Circular type cartridge enabling centrifugation and modular automatic analyzer using the same

A modular automatic analyzer using a circular type cartridge enabling centrifugation according to an exemplary embodiment of the present invention includes: a main body frame; an X-axis conveying unit which reciprocally moves in an X-axis direction with respect to the main body frame; a circular type cartridge accommodating housing which is installed with respect to the X-axis conveying unit so as to be reciprocally movable in the X-axis direction by the X-axis conveying unit, a single rotation drive unit which is installed in the circular type cartridge accommodating housing and is rotated step by step at a predetermined interval or rotated at a high speed for centrifugation, a circular type cartridge which is installed at an upper surface of the circular type cartridge accommodating housing so as to be rotatably connected to the rotation drive unit and has wells disposed to be spaced apart from each other at predetermined intervals in a circumferential direction of a disc-shaped main body, a tip lifting unit which picks up and moves a tip upward and downward, a measurement unit which measures a reaction in the well, a Z-axis drive unit which is provided with the tip lifting unit and the measurement unit and reciprocally operates in a Z-axis direction with respect to the main body frame, and a control unit C which controls an automatic immunity analyzer.

Liquid containing polymer marker, use of a polymer marker as authentication tool, and method and device for detecting a polymer marker dissolved in a liquid

The present invention relates to markers for liquids that can be used to authenticate the origin and genuineness of a liquid, preferably a bulk liquid such as fuel. For this purpose, the present invention teaches the use of a polymer capable of forming a semiconducting polymer particle (pdot) in the liquid in small amounts. The invention encompasses a liquid comprising a) a polymer that is capable of forming a semiconducting polymer particle (pdot), the concentration of the polymer being 10 ppm by weight or less, and b) an organic substance in an amount of 90% by weight or more. The invention furthermore envisages the use of such a polymer as an authenticating marker in a liquid, preferably a fuel, and a method for authenticating the genuineness and/or origin of a liquid comprising a polymer capable of forming a semiconducting polymer particle (pdot), comprising the steps i. concentrating, isolating and/or extracting the polymer capable of forming a semiconducting polymer particle (pdot); ii. aggregating the polymer or the polymer obtained in Step i. to form semiconducting polymer dots (pdots); iii. irradiating the formed pdots with electromagnetic radiation capable of exciting the pdots to emit electromagnetic radiation by fluorescence and/or phosphorescence, and iv. observing the electromagnetic radiation emitted in response to the exciting irradiation of step iii.

Instrument for processing cartridge for performing assays in a closed sample preparation and reaction system

In one embodiment, a diagnostic system includes an instrument coupled to a client device and having at least one sample processing bay. The diagnostic system has a software architecture including instrument software (ISW) associated with the instrument. The ISW receives an assay definition file (ADF) that has a control file and an assay analysis module (AAM) file. The processing bay prepares and senses the sample according to parameters in the OPUS file and then generates sensor scan data. The diagnostic system then analyzes the sensor scan data and prepares a report according to the AAM file.

Automatic response/light measurement device and method therefor
10273533 · 2019-04-30 · ·

The invention relates to an automatic response/light measurement device and a method therefor, and the purpose is to effectively and quickly perform an optical measurement relating to a reaction with high reliability without increasing a device size. The device is configured to have: a container group in which a plurality of reaction containers are arranged; a measurement mount provided with a plurality of coupling ends that are joinable with apertures of the reaction containers, and have light guide portions that optically connect with the interior of the joined reaction containers; a mount transfer mechanism; a measuring device having a measuring end having at least one light guide portion that is optically connectable to the light guide portions of the coupling ends, that is able to receive light based on an optical state within the reaction containers; an on-mount measuring end transfer mechanism; and a measurement control portion.

ANALYSIS DEVICE
20190099758 · 2019-04-04 ·

The present invention provides a new smaller analysis device that can heat an analysis chip. The analysis device includes a set section in which an analysis chip is to be set; a housing chamber that accommodates the set section; a heating section that heats the analysis chip set in the set section; and an analysis section that analyzes the analysis chip set in the set section, wherein the housing chamber serves as an analysis chamber of the analysis chip set in the set section in the state where the set section is accommodated in the housing chamber, the analysis section is disposed at a position where the analysis chip set in the set section is analyzed in the state where the set section is accommodated in the housing chamber, and the heating section is a heating plate and is disposed at a position where the analysis chip set in the set section is heated in the state where the set section is accommodated in the housing chamber.

MAGNETIC ATTRACTION INCUBATION MECHANISM OF AUTOMATIC MOLECULAR DIAGNOSTIC INSTRUMENT

A magnetic attraction incubation mechanism of an automatic molecular diagnostic instrument, includes: a magnetic attraction assembly used for magnetic attraction of a reaction chamber containing a sample liquid and an incubation assembly used for heating the reaction chamber, and further comprising: a driving device for driving the incubation assembly and the magnetic attraction assembly to be alternately close to the reaction chamber, the magnetic attraction assembly and the incubation assembly being both connected to the driving device. Switching of an incubation operation and a magnetic attraction operation can be achieved, and an incubation part and a magnetic attraction part effectively work in conjunction with each other by means of a linkage mechanism, so that the overall structure is effectively simplified, the space is saved, and a detection speed of the sample liquid can further be increased.

MEMS FRAME HEATING PLATFORM FOR ELECTRON IMAGABLE FLUID RESERVOIRS OR LARGER CONDUCTIVE SAMPLES

A heating device having a heating element patterned into a robust MEMs substrate, wherein the heating element is electrically isolated from a fluid reservoir or bulk conductive sample, but close enough in proximity to an imagable window/area having the fluid or sample thereon, such that the sample is heated through conduction. The heating device can be used in a microscope sample holder, e.g., for SEM, TEM, STEM, X-ray synchrotron, scanning probe microscopy, and optical microscopy.

Method for operating a system for the integrated and automated analysis of DNA or protein

A method for the integrated and automated analysis of DNA or protein, including a single-use cartridge, with an analysis device having a control device, and devices for capturing and processing signals, the control device carrying out a completely automatic process and evaluation of molecular diagnostic analysis via single-use cartridges (Lab-on-a-Chip). Controlling of an analysis process, which occurs in the cartridge, involve the subsequent displacement and thermostatisation of liquids with a first device, and with a second device the signals which are obtained during the analysis are processed. The first and the second devices are synchronized in such a manner that the analysis process of the sample can be carried out in a totally integrated manner thus producing an immediate result.

Systems and methods for determining presence and/or characteristics of target analytes in a sample

A cartridge for providing a target analyte for detection is described. One such exemplar cartridge includes a base portion including: (1) a receiving area disposed at or near a center region of the base portion; (2) multiple reaction wells disposed outside the center region or radially disposed at or near a perimeter of the base portion; and (3) multiple connecting tracks that substantially linearly extend from a region at or proximate to the receiving area to the multiple reaction wells and designed to convey a sample including the target analyte from the receiving area to the multiple reaction wells, each of which are configured to transform the sample to a detectable sample. Systems and methods of reacting and detecting the sample including the target analyte are also described.