G01N2035/00574

AUTOMATED LIQUID-PHASE IMMUNOASSAY APPARATUS

Disclosed is an automated liquid-phase immunoassay apparatus used with a cuvette having a plurality of chambers containing a reagent necessary for detection of an analyte in a biological specimen. The apparatus includes a movable cuvette module equipped with the cuvette, an optical reading module for optical assaying of a material resulting from a reaction between the specimen and the reagent, and a dispenser module which is positioned on the cuvette module and which dispenses the specimen and the reagent to the plurality of chambers of the cuvette and washes the specimen and the reagent therefrom.

Apparatuses and methods for mixing fluid or media by vibrating a pipette using transient and steady-state intervals

In an embodiment, an immunochemistry analysing system includes a source of paramagnetic particles, a source of fluid, a cuvette configured to receive the paramagnetic particles and the fluid, a pipette configured to (i) translate so that at least a portion of the pipette is located within the cuvette and (ii) dispense at least one of the paramagnetic particles and the fluid into the cuvette so that the paramagnetic particles and the fluid can be mixed within the cuvette, a motor configured to move the pipette while located in the cuvette, and a control unit configured to vary a motor drive of the motor to cause the pipette to mix the fluid with the paramagnetic particles within the cuvette.

Particle dispersion device and particle dispersion method
11169057 · 2021-11-09 · ·

A particle dispersion method for dispersing particles (500) fixed on the inner surface of a container (12) into a liquid. The particle dispersion method includes a discharge step of discharging a liquid into the container (12). The container (12) has a cylindrical main body part (310), and an inclined part (311) having an inner diameter that decreases from the main body part (310) side to the bottom part side and having a constant angle relative to the central axis of the container. In the discharge step, the liquid is discharged from above the inclined part (311) toward the inclined part (311) on the side opposite the particles (500) fixed to the inner surface of the container (12) across the central axis (300) of the container (12).

BIOLOGICAL MATERIAL PURIFICATION DEVICE AND PROCEDURE USING MAGNETIC BEADS
20220280948 · 2022-09-08 ·

An automated workstation configured for magnetic bead nucleotide purification may be provided with a bead mover device, a working nest and a plate hotel. In some embodiments, the bead mover device includes a housing, a magnetic head assembly having an array of downwardly extending elongated magnets and a leadscrew located within the housing and configured to move the magnetic head assembly along a vertical axis. The working nest may be located on the frontside of the bead mover housing below the magnetic head assembly, and the plate hotel may be located on the backside of the housing and configured to hold a plurality of fixtures when not in use on the working nest. Methods of use are also disclosed.

APPARATUS AND METHOD FOR PLACING MIXING BALLS INTO PHARMACEUTICAL CONTAINERS

The invention relates to an apparatus (10) for placing mixing balls (1) into pharmaceutical containers (2), comprising a transport device (30) for conveying, preferably intermittently, the containers (2), and comprising a feed device (45) for the mixing balls (1), wherein the feed device (45) can be moved between a position for removing mixing balls (1) from a storage means (46) and a position for transferring the mixing balls (1) into the containers (2).

AUTOMATED LIQUID-PHASE IMMUNOASSAY APPARATUS

Disclosed is an automated liquid-phase immunoassay apparatus used with a cuvette having a plurality of chambers containing a reagent necessary for detection of an analyte in a biological specimen. The apparatus includes a movable cuvette module equipped with the cuvette, an optical reading module for optical assaying of a material resulting from a reaction between the specimen and the reagent, and a dispenser module which is positioned on the cuvette module and which dispenses the specimen and the reagent to the plurality of chambers of the cuvette and washes the specimen and the reagent therefrom.

Detection apparatus and detection method

Disclosed is a detection apparatus that transfers magnetic particles through a plurality of chambers in a cartridge which includes the plurality of chambers and a channel connecting between the plurality of chambers, and that causes the magnetic particles to carry a complex of a test substance and a labelling substance, to detect the test substance on the basis of the labelling substance in the complex. The detection apparatus includes: a rotation mechanism configured to rotate the cartridge about a rotation shaft; a magnet configured to collect the magnetic particles in the chambers; a movement mechanism configured to move the magnet in a direction different from a circumferential direction of a circle in which the rotation shaft is centered; a detector configured to detect the test substance; and a controller programmed to control the rotation mechanism and the movement mechanism so as to transfer the magnetic particles from one of the chambers to another one of the chambers.

Sample Plate Systems and Methods
20210190779 · 2021-06-24 · ·

A sample plate comprising a sample well is disclosed. The sample well can comprise one or more bead retaining chambers. Also provided herein is a method of using the sample plate and kits comprising the sample plate.

Automated liquid-phase immunoassay apparatus

Disclosed is an automated liquid-phase immunoassay apparatus used with a cuvette having a plurality of chambers containing a reagent necessary for detection of an analyte in a biological specimen. The apparatus includes a movable cuvette module equipped with the cuvette, an optical reading module for optical assaying of a material resulting from a reaction between the specimen and the reagent, and a dispenser module which is positioned on the cuvette module and which dispenses the specimen and the reagent to the plurality of chambers of the cuvette and washes the specimen and the reagent therefrom.

DETECTION APPARATUS AND DETECTION METHOD

Disclosed is a detection apparatus that transfers magnetic particles through a plurality of chambers in a cartridge which includes the plurality of chambers and a channel connecting between the plurality of chambers, and that causes the magnetic particles to carry a complex of a test substance and a labelling substance, to detect the test substance on the basis of the labelling substance in the complex. The detection apparatus includes: a rotation mechanism configured to rotate the cartridge about a rotation shaft; a magnet configured to collect the magnetic particles in the chambers; a movement mechanism configured to move the magnet in a direction different from a circumferential direction of a circle in which the rotation shaft is centered; a detector configured to detect the test substance; and a controller programmed to control the rotation mechanism and the movement mechanism so as to transfer the magnetic particles from one of the chambers to another one of the chambers.