G01N2035/0401

AUTOMATED STAINING SYSTEM AND REACTION CHAMBER

A processor assembly including a core module operable to expose a sample on a slide; a staining module operable to apply a stain to the exposed sample; and a robotic transfer mechanism to transfer the slide from the core module to the staining module. Also, an apparatus including a rectangular body having an open rear end and an opposite front end; a flange having a first side and a second side, wherein the first side of the flange is coupled to the front end of the body; and a pair of legs extending from second side of the flange, wherein the pair of legs are operable to engage opposite side edges of a slide. A method comprising: exposing a sample on a slide in a core module of a processor assembly; robotically transferring the slide from the core module of the processor assembly to a staining module of the processor assembly; applying a reagent to the exposed sample in the staining module by a thermal inkjet printing process; and after applying the reagent, robotically transferring the slide back to the core module.

Kits And Devices For Detecting Analytes
20230120417 · 2023-04-20 ·

The invention provides devices that improve tests for detecting specific cellular, viral, and molecular targets in clinical, industrial, or environmental samples. The invention permits efficient detection of individual microscopic targets at low magnification for highly sensitive testing. The invention does not require washing steps and thus allows sensitive and specific detection while simplifying manual operation and lowering costs and complexity in automated operation. In short, the invention provides devices that can deliver rapid, accurate, and quantitative, easy-to-use, and cost-effective tests.

Automatic Analysis System
20230123687 · 2023-04-20 ·

The purpose of the present invention is to provide an automatic analysis system which, even when a large number of quality control samples is necessary, reduces the time necessary for quality control. To this end, this automatic analysis system is provided with multiple analysis devices (190), a conveyance unit (120) to which the analysis devices (190) are connected, and an operation unit (101) which operates the conveyance unit (120) to convey samples to the analysis device (190), wherein the automatic analysis system has a common storage cabinet (210) for storing the quality control samples that can be supplied to the multiple analysis devices (190), and in accordance with a rule registered in advance for each of the multiple analysis devices (190), the operation unit (101) operates the storage cabinet (210) to automatically convey a quality control sample to an analysis device (190).

METHOD AND LABORATORY SYSTEM TO PROVIDE CONTROL SAMPLES FOR VALIDATING A DIAGNOSTICS TEST

A computer implemented method to allocate control samples for validating a diagnostic test within a laboratory system is provided. The laboratory system comprises a storage, a transport system, and at least two analyzers. A total number of control sample aliquots and an aliquot volume for each control sample aliquot is determined based on a validation time schedule. Information is presented for distributing the total control sample volume into the determined total number of control sample aliquots with the determined aliquot volumes. Information is also presented for distributing the control sample aliquots to one or more of the at least two analyzers according to the validation time schedule.

NUCLEIC ACID ANALYSIS DEVICE

The present invention provides a nucleic acid analysis device that, even when a plurality of flow cells is handled, does not require an increase in the required movement amount, and can be reduced in size by reducing the size of a stage mechanism. This nucleic acid analysis device is characterized by having a sample container containing a nucleic acid sample to be analyzed, an imaging means for observing the nucleic acid sample, and a stage mechanism for moving the sample container, and is characterized in that the stage mechanism has two translation means and at least one rotation means, one of the two translation means is disposed on the upper surface of the rotation means, and the other is disposed on the lower surface of the rotation means.

SAMPLE CONTAINER CARRIER
20170248624 · 2017-08-31 ·

A sample container carrier for transporting sample containers, for example test tubes and/or vials, in a laboratory automation system is presented. The sample container carrier comprises a body having a hollow center with a central axis (A). The hollow center is adapted for receiving a lower end of a sample container. The sample container carrier also comprises at least three resiliently deformable and/or displaceable upper retaining elements. The upper retaining elements are distributed about the central axis (A) and adapted to clamp a sample container inserted in the hollow center of the body. The upper retaining elements are made of plastic. A method for manufacturing a sample container carrier is also presented. At least the upper retaining elements are formed by injection molding. A laboratory sample distribution system having a number of sample container carriers and a laboratory automation system comprising a laboratory sample distribution system are also presented.

SAMPLE CONTAINER CARRIER
20170248623 · 2017-08-31 ·

A sample container carrier for transporting sample containers, for example test tubes and/or vials, in a laboratory automation system is presented. The sample container carrier comprises a body having a hollow center with a central axis. The hollow center accommodates a lower end of a sample container. The sample container carrier also comprises three resiliently deformable and/or displaceable first retaining elements mounted to the body. The first retaining elements, distributed about the central axis, clamp a sample container inserted in the hollow center. The sample container carrier also comprises three resiliently deformable and/or displaceable second retaining elements mounted to the body. The second retaining elements, distributed about the central axis, clamp the sample container inserted in the hollow center underneath the three first retaining elements. The second retaining elements are arranged at least partly inside the hollow center.

Dispatching device, sample distribution system and laboratory automation system

A dispatching device for dispatching sample containers received in respective sample container carriers from a transport surface to an external position and/or from the external position to the transport surface is presented. The dispatching device has a tube and a capsule, a conveying surface with an electromagnetic actuator being formed in the capsule. A sample distribution system with such a dispatching device and a laboratory automation system with such a sample distribution system are also presented.

Systems and Methods for Automated Analysis

Aspects of the present disclosure include sample analysis methods and systems. According to certain embodiments, provided are methods of analyzing samples in an automated sample analysis system. The methods include introducing samples and sample preparation cartridges into the system, isolating and purifying an analyte (e.g., nucleic acids and/or proteins) present in the samples at a sample preparation station, and performing analyte detection assays in assay mixtures that include the purified analyte. Also provided are automated sample analysis systems that find use, e.g., in performing the methods of the present disclosure. In certain aspects, the methods and systems provide for continuous operator access during replenishment or removal of one or any combination of samples, bulk fluids, reagents, commodities, waste, and/or the like.

Laboratory automation system

A laboratory automation system for processing sample containers containing laboratory samples and/or for processing the samples is presented. The laboratory automation system comprises a digital camera configured to take an image of the sample container together with a calibration element. The image comprises image data related to the sample container and image data related to the calibration element. The laboratory automation system also comprises an image processing device configured to determine geometrical properties of the sample container depending on the image data related to the sample container and the image data related to the calibration element.