Patent classifications
G01N35/1011
Systems and methods for automated preparation of biological specimens
An automated system for processing a sample contained in a liquid sample container includes an automated tool head configured to rotate about a first axis, and to translate along a second axis different than the first axis, an analytic element positioner having an analytic element holder configured to releasably grip an analytic element, and a specimen transfer device carried by the tool head, wherein the tool head is configured to automatically position a working end of the specimen transfer device to obtain a specimen from a sample container held in the sample container holder, and to transfer the obtained specimen to an analytic element held by the analytic element holder, respectively, through one or both of rotation of the tool head about the first axis and translation of the tool head along the second axis.
Hematocrit and liquid level sensor
A fluid aspiration probe apparatus for automatic fluid testing equipment includes a pair of electrodes mounted on a distal probe tip. The electrodes are coupled to an impedance measurement apparatus via conductive pathways along the probe. The impedance measurements and probe tip height are monitored as the probe tip is lowered into a fluid sample. Boundaries between layers of fluid in the container are detected by recognizing sudden changes in the impedance measurements and heights of the boundaries are determined by tracking the position of probe tip when the sudden changes of impedance occur.
Systems and methods for pipette robots
Systems and methods applicable, for instance, to pipette robots. A pipette robot can perform one or more operations regarding deck calibration, one or more operations regarding pipette tip/probe calibration, one or more operations regarding pipette tip pick up, and/or one or more operations regarding tip ejection.
System and method for filling a closed container with a fixative solution
The present invention relates to a method and a system (400) for filling a closed container (200) with a fixative solution. The system comprises a container (200) comprising a container body (230) for receiving a biological specimen, a lid (220) for selectively closing the container body (230) and a port (100) forming a unidirectional barrier in a direction from the inside (IC) to the outside (OC) of the closed container (200). The system further comprises a dispensing apparatus (500) having a filling nozzle (300) for dispensing the fixative solution. The filling nozzle (300) is relatively moveable with respect to the container (200) between a retracted position and a filling position to fill the container (200) with the fixative solution.
Methods and apparatus to calibrate a positional orientation between a robot gripper and a component
Methods of calibrating a position of a component include providing a robot with a gripper and crush and crash sensors, a calibration tool coupled to the gripper, and the component, which has a recess and a crush zone. The methods also include moving the gripper in a first direction to sense contact between the calibration tool and the crush zone, recording the contact position, and moving the gripper to insert the tool into the recess. The gripper is then moved in second directions to sense contact between the tool and the recess and moved in third directions to also sense contact between the tool and the recess. The methods further include recording and processing the contact positions to determine a surface location in the first direction and a physical center of the recess. Robot calibration apparatus for performing the method is also disclosed, as are other aspects.
DEVICE AND METHOD FOR ATTESTING THE OPERATIONS OF AN IN-VITRO DIAGNOSTIC DEVICE
Device (100) for attesting the operations of an in-vitro diagnostic device (50) comprising: a block (101) for capturing a plurality of frames of the tip (51); a block (102) for storing the plurality of frames; a block (103) for evaluating the right hooking of the tip (51) to the in-vitro diagnostic device (50); a block (104) for evaluating the volume of a liquid contained in the tip (51); a block (105) for carrying out verification before the operation of dispensing the liquid; a block (106) for carrying out a post-dispensing verification; blocks (107, 108) for emitting electronic signals; a block (109) for integrating a system for managing the errors; a block (110) for saving the data; a block (111) for communicating with the in-vitro diagnostic device (50).
SYSTEMS AND METHODS FOR PIPETTE ROBOTS
Systems and methods applicable, for instance, to pipette robots. A pipette robot can perform one or more operations regarding deck calibration, one or more operations regarding pipette tip/probe calibration, one or more operations regarding pipette tip pick up, and/or one or more operations regarding tip ejection.
Automatic Analysis Apparatus
To provide a high-throughput automatic analysis apparatus at a lower cost. The automatic analysis apparatus includes an incubator which accommodates a plurality of reaction vessels; a specimen dispensing mechanism which dispenses a specimen into each of the plurality of reaction vessels; a mounting unit which mounts a dispensing tip on the specimen dispensing mechanism; a suction unit which sucks a specimen from a specimen vessel containing the specimen by means of the specimen dispensing mechanism having the dispensing mounted thereon; a discharging unit which is provided in the incubator and discharges the specimen from the specimen dispensing mechanism to the reaction vessel; a disposal unit which discards the dispensing tip; a sensor which detects whether the dispensing tip is mounted to the specimen dispensing mechanism; and a control unit which controls the specimen dispensing mechanism. The mounting unit, the suction unit, the discharging unit, and the disposal unit are arranged along a movement path of the specimen dispensing mechanism. The sensor is arranged so as to be able to detect the dispensing tip at a position sandwiched between any two of the mounting unit, the suction unit, the discharging unit, and the disposal unit.
Pipettor system
Various embodiments include a system having a pipetting chamber, a set of pipettor cartridges docked in the pipetting chamber, a gantry system mounted on a ceiling within the pipetting chamber, the gantry system including at least one stationary track aligned in a first direction, and a movable track aligned in a second direction distinct from the first direction, the movable track coupled to the at least one stationary track, and a carrier configured to transport each of the set of pipettor cartridges to a pipetting location within the pipetting chamber, the carrier configured to move each pipettor cartridge in a third direction perpendicular to both the first and second directions.
Automated specimen deposition systems and associated methods
Systems and methods that enable automated spray deposition of biological specimens carried on microscope slides are described herein. Aspects of the technology are directed, for example, to automated specimen deposition systems and methods of generating high-quality, reproducible specimen-bearing microscope slides in automated processing systems.