A diagnostic device with an improved optical system is disclosed. The disclosed in vitro diagnostic device has a housing with an inner bottom surface having an arc shape that rises upward from one side where the light source is arranged to the other side where the cartridge sensing surface is arranged. This device may include light sources with different wavelengths arranged on one side of the lower housing. Additionally, it may include an upper housing that is coupled to the upper surface of the lower housing and has a cartridge insertion space for a cartridge with a plurality of wells. The upper housing includes an observation window that covers at least the plurality of sensing hole areas to allow optical observation of the inside of the wells.

The present invention relates to a method and device for determining a property of an ambient environment. The device comprises a plasmonic sensing element; a first light source for illuminating a first and a second light sensor, the first sensor via the plasmonic sensing element; a second light source for illuminating the light sensors; circuitry for executing: a control function controlling light sources, a function receiving a measurement from the first sensor, and a first signal from the second sensor, a function receiving a reference from the first sensor, and a second signal from the second sensor, a function determining the property by comparing the measurement and reference signals, and the control function further controlling light sources such that a relation of intensities of light emitted by the light sources is constant over time.

In an example, a photometric imaging device comprises a light source to illuminate a target area including a set of fiducials, an imaging device to capture images of the set of fiducials illuminated by the light source with different image viewing settings, and a controller. The controller is to: control the light source to subsequently illuminate the set of fiducials with the different image viewing settings; determine locations of the set of fiducials on the captured images; determine pixel deviations between the determined locations; and determine offset data based at least in part on the determined pixel deviations.

A method for calibrating an optics module on a chemistry analyzer is disclosed. The method includes measuring a first reflectance value for a first chemistry slide, wherein the first chemistry slide comprises a first chemical substance, and wherein the first chemical substance is associated with a first global reflectance reference value. The method includes generating a first comparison of the first reflectance value and the first global reflectance reference value. The method includes measuring a second reflectance value for a second chemistry slide, wherein the second chemistry slide comprises a second chemical substance, and wherein the second chemical substance is associated with a second global reflectance reference value. The method includes generating a second comparison of the second reflectance value and the second global reflectance reference value. The method includes based on at least one of the first comparison or the second comparison, calibrating one or more components of the optics module.