This invention relates generally to devices, systems, and methods for performing biological assays by using indicators that modify one or more optical properties of the assayed biological samples. The subject methods include generating a reaction product by carrying out a biochemical reaction on the biological sample introduced into a device and reacting the reaction product with an indicator capable of generating a detectable change in an optical property of the biological sample to indicate the presence, absence, or amount of analyte suspected to be present in the sample.

Proposed are a device and method for checking for a surface defect, using an image sensor. The device can increase accuracy in detecting defects of various types, shapes, or directions, and include: a frame part for providing a transport path of an object to be checked, along the lengthwise direction parallel to the ground surface; a transport part provided on one side of the frame part so as to transport the object to be checked, along the transport path; and an image sensor part provided in the middle of the transport path so as to capture an image of the surface of the object to be checked, from above the transported object to be checked.

Disclosed is an autofluorescence quenching device that: quenches only autofluorescence without quenching fluorescence that is originally desired to be observed in a tissue section in a short time; does not emit noise in various wavelength regions; is capable of controlling a temperature increase; can be used repeatedly with a simple operation; and can stably quenches autofluorescence. The autofluorescence quenching device for a sample includes: a sample placement unit; and an irradiation unit mounted on the sample placement unit. The sample placement unit includes: a flat plate; one or more sample placement recesses each in which a sample is to be placed and which are provided in the flat plate; and a cooling means for cooling the sample placement recesses. The irradiation unit includes one or a plurality of white LED illuminations placed above the respective sample placement recesses.

An illumination system includes a measurement stage on which a measurement target is located, a light-providing part having illumination sections providing multi-directional incident lights to the measurement target, a light-receiving part receiving single-directional reflection lights reflected by the measurement target according to the multi-directional incident lights, and a processing part that performs acquiring a first distribution of intensities the single-directional reflection lights with respect to the multi-directional incident lights, acquiring, from the first distribution, a second distribution of intensities of multi-directional reflections lights with respect to a single-directional incident light, and determining material of the measurement target based on parameters of the second distribution. A method of recognizing material using the illumination system and a computer readable non-transitory recording medium recording a program embodying the method are provided.

A device and a method for foam analysis. The device comprises a cylindrical sample container with a transparent wall, at least one illumination device and a camera, which. can be moved on a track. The curvature of the web runs parallel to the wall of the container. The illumination device directs a light beam onto the wall of the cylindrical sample container at an angle which deflects the light beam into the sample vessel when liquid is present on the inside of the sample container and causes a total reflection when air or another gas fills the foam pores. The camera and the illumination unit are moved along the path in the circumferential direction of the wall of the sample container such that a region to be examined is illuminated in steps or in a continuous progression and the camera records the totally reflected light in the region.

A device for optical detection of analytes in a sample includes at least two optoelectronic components. The optoelectronic components include at least one optical detector configured to receive a photon and at least one optical emitter configured to emit a photon. The at least one optical emitter includes at least three optical emitters disposed in a flat, non-linear arrangement, and the at least one optical detector includes at least three optical detectors disposed in a flat, non-linear arrangement. The at least three optical emitters and the at least three optical detectors include at least three different wavelength characteristics.

A microscope illumination device includes at least one light source and a light conversion element. The light conversion element is configured as at least one optical waveguide which contains different fluorescent materials each having different emission ranges. The at least one light source is arranged such that emission light for exciting the fluorescent materials from the at least one light source is coupled into the light conversion element. The light conversion element is configured such that light emitted by the fluorescent materials is guided to a light exit face of the light conversion element and is decoupled at the light exit face as illumination light.

A device for measuring radiation backscattered by a sample including: at least one light source that is configured to emit a light beam, along an axis of incidence, towards a surface of the sample so as to form, on said surface, an elementary illumination zone; an image sensor for forming an image of the radiation backscattered by the sample when the latter is illuminated by the light source, the image sensor lying in a detection plane; a bundle of optical fibres, extending, along an extension axis, between a proximal surface and a distal surface, the proximal surface being applied against the image sensor, the distal surface being configured to be applied against the surface of the sample;
wherein the light source is arranged around the bundle of optical fibres, and wherein the distance between the light source and the bundle of optical fibres is less than 1 mm.

A quality control station (2) for a sheet element processing machine, having at least one camera (6) arranged for capturing images of sheet elements (4) transported through the quality control station (2), and further having an illumination unit (5) with at least one light emitter (16) and two reflectors (12, 14), the illumination unit (5) directing light onto a viewing area of the camera (6) such that the illumination intensity is constant despite changing media thickness. An illumination unit for such quality control station is disclosed.

The invention relates to a system (15) for observing a plate (10) including wells (20), including, for each well (20): a source (40) comprising a light-emitting diode (60) capable of producing a light ray, a pinhole (70), and a light integrator (65), an optical sensor (185) able to collect the optical signal from the well (20), the system (15) being such that: a ratio between the length and the average transverse dimension (Dt) of each light integrator (65) is greater than or equal to 2.2, or at least one optical axis is off-centered relative to the propagation line, the ratio between the length and the average transverse dimension of the integrator being greater than or equal to 1.5.