Among other things, the present invention is related to devices and methods for improving optical analysis of a thin layer of a sample sandwiched between containing between two plates.

A method for determining properties of a laboratory sample contained in a laboratory sample container is presented. The method comprises measuring projections of the laboratory sample container comprising the laboratory sample by irradiating light to the laboratory sample container at different projection angle and determining the properties by tomographic reconstruction based on the projections.

A method for determining properties of a laboratory sample contained in a laboratory sample container is presented. The method comprises measuring projections of the laboratory sample container comprising the laboratory sample by irradiating light to the laboratory sample container at different projection angle and determining the properties by tomographic reconstruction based on the projections.

The present disclosure relates to a substrate defect measuring apparatus for detecting defects inside a substrate by photoluminescence and detecting defects outside the substrate by using the scattering of incident light for generating photoluminescence, and provides an apparatus for constituting an optical system in order to measure scattered and/or reflected light together in a procedure of measuring the photoluminescence, thereby shortening a measurement time.

Apparatus and methods are described including placing a sample into a sample carrier that comprises a plurality of regions having upper and lower surfaces, having respective heights that are different from each other, and being configured such that cells form a monolayer, the monolayer within respective regions of the sample carrier having respective, different densities from each other, due to the respective regions of the sample carrier having respective heights that are different from each other. Microscopic images are acquired of each of the plurality of regions. Measurements are performed upon cell types that have a relatively high density upon microscopic images of a region of the sample chamber having a relatively low height, and measurements are performed upon cell types that have a relatively low density upon microscopic images of a region of the sample chamber having a relatively great height. Other applications are also described.

Apparatus and methods are described for determining a property of a biological sample. A sample carrier includes a glass substrate configured to define a first surface of a sample chamber that is configured to receive the sample, and a plastic substrate configured to define a second surface of the sample chamber. The height of the sample chamber at each location within the sample chamber is defined by a gap between the first surface and the second surface. An adhesive adheres the glass substrate to the plastic substrate. The plastic substrate is shaped such that the sample chamber defines a first region and a second region, with the sample chamber defining a predefined variation in height between the first region and the second region. Other applications are also described.

This disclosure is directed to exemplary embodiments of systems, methods, techniques, processes, products and product components that can facilitate users making improved absorbance or fluorescence measurements in the field of spectroscopy with reduced (minimal) sample waste, and increased throughput, particularly in the study of biological sciences. A method and device for photometric measurement of liquids. The method includes the steps of: The method includes the steps of; providing a pipette tip, the pipette tip being made of an optically clear body having an outer wall and an inner wall, the inner wall defining an inner space for receiving a liquid sample, the inner space providing a cross-sectional path length for light; positioning the pipette tip between a light source and a light collector; measuring light transmission through the liquid sample; adjusting the inner space of the pipette tip to change the cross-sectional length, and measuring light transmission through the liquid sample. This can be accomplished by moving the light source from a first position to at least a second position to provide a plurality of cross-sectional path lengths through the liquid sample or by moving the pipette tip from a first position to at least a second position to provide a plurality of cross-sectional path lengths through the liquid sample.

Among other things, the present invention is related to devices and methods for improving optical analysis of a thin layer of a sample sandwiched between containing between two plates.

Device for improving an optical detecting smoke apparatus and implementing thereof. Apparatus and methods for detecting the presence of smoke in a small, long-lasting smoke detector are disclosed. Specifically, the present disclosure shows how to build one or more optimized blocking members in a smoke detector to augment signal to noise ratio. This is performed while keeping the reflections from the housing structure to a very low value while satisfying all the other peripheral needs of fast response to smoke and preventing ambient light. This allows very small measurements of light scattering of the smoke particles to be reliable in a device resistant to the negative effects of dust. In particular, geometrical optical elements, e.g., cap and optical defection elements, are disclosed.

Among other things, the present invention is related to devices and methods for improving optical analysis of a thin layer of a sample sandwiched between containing between two plates.