A method includes enabling a first radiating source configured to output a first beam, enabling a second radiating source configured to output a second beam, directing the first beam to irradiate a sample at an angle of incidence of ten degrees of Brewster's angle or less, directing the second beam to irradiate a sample at an angle of incidence of ten degrees or less (the first beam and the second beam only pass through a single scan lens before irradiating the sample), measuring scattered radiation data resulting from the irradiation of the sample by the second beam, measuring reflected radiation resulting from irradiation of the sample by the first beam, and determining the presence of a defect based at least in part on one of the measurements. The radiating sources may be enabled in an alternating fashion so to improve resulting measurement performance.

A microscope device (1) comprises: a first microscope part (10) including a first illumination optical system that irradiates a sample with a first illumination light toward a first direction and a first detection optical system that receives detection light from the sample in response to the irradiation with the first illumination light and guides the detection light to a first detector; and a second microscope part (50) including a second illumination optical system that irradiates the sample with a second illumination light toward a second direction and a second detection optical system that receives detection light from the sample in response to the irradiation with the second illumination light and guides the detection light to a second detector, the second direction being different from the first direction, wherein the microscope device comprises any one of the predetermined features.

This disclosure is directed to exemplary embodiments of systems, methods, techniques, processes, products and product components that can facilitate users making improved absorbance or fluorescence measurements in the field of spectroscopy with reduced (minimal) sample waste, and increased throughput, particularly in the study of biological sciences. A measuring system is provided having: a base unit with a means for locating a pipette tip; a pipette tip designed to interact with the base unit for purposes of accurate pipette tip positioning; at least one light supplying unit positioned to supply light to a liquid sample in the pipette tip and at least one light collecting unit positioned to collect light from a liquid sample in the pipette tip.

Among other things, the present invention is related to devices and methods for improving optical analysis of a thin layer of a sample sandwiched between containing between two plates.

Among other things, the present invention is related to devices and methods for improving optical analysis of a thin layer of a sample sandwiched between containing between two plates.

A method includes illuminating an overlay target with a plurality of measurement cells. The method further includes receiving time-varying interference signals from a first and second photodetector as an overlay target is scanned along a stage-scan direction by a translation stage when implementing a metrology recipe. The overlay target may include a plurality of measurement cells, where each measurement cell includes a grating-over-grating structures including a first-layer grating feature on a first layer of the sample and a second-layer grating feature on a second layer of the sample in an overlapping region. The first-layer grating feature and the second-layer grating feature may have a similar pitch. The method includes determining one or more differential signals between the first photodetector and the second photodetector for each measurement cell of the plurality of measurement cells. The method includes determining an overlay measurement based on the determined one or more differential signals.

A system may include a light source, to generate a probe signal, comprising incident radiation; an optical probe, to direct the incident radiation through a fluid sample; a motor, to move the optical probe along a probe axis, to change a path length of the incident radiation through the fluid sample; and a detector, to receive the incident radiation as attenuated radiation after passing through the fluid sample. The system may include a control system, arranged to: initiate an absorbance measurement by directing movement of the optical probe along the probe axis; direct the light source to emit the incident radiation; and automatically adjust at least one measurement parameter of a set of measurement parameters for the sample measurement, based upon a slope parameter m, wherein m is derived from a rate of change in an intensity of the attenuated radiation with a change in the path length.

The present application discloses an apparatus for measuring the concentration of ozone within a fluid and includes a conduit defining at least one passage therein, the conduit has at least one reflective coating selective applied thereto and defining one or more transmission regions on the conduit, a multi-wavelength light source system having at least one light source configured to direct at least one optical signal having a first wavelength through an ozonated fluid within the conduit and at least one UV light source configured to direct at least one UV optical signal having a second wavelength band through the ozonated fluid wherein the optical signal and the UV optical signal traverse through the conduit along different optical paths via at least one reflection from the reflective coating applied to the conduit, and at least one detector positioned proximate to the transmission regions formed on the conduit and configured to detect the optical signal and the UV signal thereby permitting measurement of the concentration of ozone within an ozonated fluid.

The embodiments of the present invention disclose a method, system, device and electronic apparatus for measuring concentration of water and lipids components. The method includes acquiring an optical absorption coefficient of a sample to be measured irradiated by a light source of at least two wavelengths, wherein a wavelength of the light source of at least two wavelengths is not greater than 1000 nm; and acquiring an extinction coefficient of water irradiated by the light source of at least two wavelengths and an extinction coefficient of lipids irradiated by the light source of at least two wavelengths; determining a concentration of water in the sample to be measured and a concentration of lipids in the sample to be measured, respectively, based on the optical absorption coefficient of the sample to be measured irradiated by the light source of at least two wavelengths, the extinction coefficient of water irradiated by the light source of at least two wavelengths, and the extinction coefficient of lipids irradiated by the light source of at least two wavelengths.