An optical setup to detect fluorescence in samples is described, taking advantage of the geometry of sample vials to optimize both the excitation of fluorescence within said sample vials and the detection of fluorescence from the sample as it is emitted. Said optical geometry can be adapted for different sample containers and can be used in a variety of optical setup, both in single sample test systems as well as sample arrays.

Method and gas analyzer for measuring the concentration of a gas component in a measurement gas, a wavelength-tunable laser diode is actuated with a current, one part of the light generated by the laser diode is guided through the measurement gas to a measuring detector to generate a measuring signal, the other part of the light is guided to a monitor detector to generate a monitor signal, the current is varied in periodically consecutive scanning intervals to scan an absorption line of interest of the gas component as a function of the wavelength, the current is further modulated with a radio-frequency noise signal having a lower cut-off frequency selected as a function of the properties of the laser diode and high enough to ensure no wavelength modulation occurs and the measuring signal is correlated with the monitor signal and then evaluated to generate a measurement result.

An illuminator/collector assembly can deliver incident light to a sample and collect return light returning from the sample. A sensor can measure ray intensities as a function of ray position and ray angle for the collected return light. A ray selector can select a first subset of rays from the collected return light at the sensor that meet a first selection criterion. In some examples, the ray selector can aggregate ray intensities into bins, each bin corresponding to rays in the collected return light that traverse within the sample an estimated optical path length within a respective range of optical path lengths. A characterizer can determine a physical property of the sample, such as absorptivity, based on the ray intensities, ray positions, and ray angles for the first subset of rays. Accounting for variations in optical path length traversed within the sample can improve accuracy.

An active remote sensing system is provided with an array of laser diodes that generate light directed to an object having one or more optical wavelengths that include at least one near-infrared wavelength between 700 nanometers and 2500 nanometers. One of the laser diodes pulses with pulse duration of approximately 0.5 to 2 nanoseconds at repetition rate between one kilohertz and about 100 megahertz. A beam splitter receives the laser light, separates the light into a plurality of spatially separated lights and directs the lights to the object. A detection system includes a photodiode array synchronized to the array of laser diodes and performs a time-of-flight measurement by measuring a temporal distribution of photons received from the object. The time-of-flight measurement is combined with images from a camera system, and the remote sensing system is configured to be coupled to a wearable device, a smart phone or a tablet.

An optical system measures one or more physiological parameters with a wearable device that includes a light emitting diode (LED) source including a driver and a plurality of semiconductor sources that generate an output optical light. One or more lenses deliver a lens output light to tissue of a user. A detection system receives at least a portion of the lens output light reflected from the tissue and generates an output signal having a signal-to-noise ratio. The detection system comprises a plurality of spatially separated detectors and an analog to digital converter. The detection system increases the signal-to-noised ratio by comparing a first signal with the LEDs off to a second signal with the LEDs on. An imaging system including a Bragg reflector is pulsed and has a near infrared wavelength. A beam splitter splits the light into a sample arm and a reference arm to measure time-of-flight.

Disclosed is a method for measuring the absorbance of light of a substance in a solution in a measuring cell (23; 223′), said method comprising the steps of: transmitting (S1) a first light beam (27; 27′) from a light source (25; 25′) towards a beam splitter (29; 29′); dividing (S3) the first light beam (27; 27′) into a signal light ray (31; 31′) and a reference light ray (33; 33′) by the beam splitter (29; 29′); modulating (S5) the signal light ray (31; 31′); modulating the reference light ray (33; 33′); providing (S9) the measuring cell (23; 23′) such that the signal light ray (31; 31′) passes through the measuring cell; detecting (S11) a signal in a detector (39; 39′), which signal is the combined signal intensity of the signal light ray (31; 31′) and the reference light ray (33; 33′) detected by the detector (39; 39′); performing synchronous detection (S15) of the detected signal in order to reconstruct the intensities of the signal light ray (31; 31′) and the reference light ray (33; 33′) from the combined signal detected by the detector (39; 39′), said synchronous detection being based on the modulation performed to the signal light ray and the reference light ray. Disclosed also is a measuring device for carrying out said method.

The present disclosure is drawn to devices and systems for target detection in samples (e.g., food samples and clinical samples). The allergen detection system includes a sampler, a disposable analytic cartridge and a detection device with an optimized optical system. The allergen detection utilizes nucleic acid molecules as detection agents and detection probes.

An apparatus includes an optical emitter configured to emit a first optical signal along an optical path towards a target object in an outdoor environment. The apparatus includes an optical detector positioned collinearly with respect to the optical emitter. The optical detector is configured to detect a second optical signal that is retro-reflected from the target object. The apparatus includes a lock-in amplifier coupled to the optical detector. The lock-in amplifier is configured to generate, based on the first optical signal and the second optical signal, a signal indicative of a retro-reflectivity of the target object in the outdoor environment.

An objective of the present invention is to provide an optical measurement device capable of performing remote optical measurement. An optical measurement device may include a light source that generates irradiation light with a beam shape, a beam control unit configured to control an irradiation direction of the irradiation light L1, a condensing unit configured to condense returned light generated by irradiating a part of a measurement target with the irradiation light, and a detection unit configured to detect information regarding the measurement target included in the returned light condensed by the condensing unit. The beam control unit can control the irradiation direction of the irradiation light for measurement to any direction, and thus the condensing unit can efficiently receive the faint returned light from the measurement target.

A detection unit receives an optical signal that has passed through a space to be measured. A spectrum extraction unit extracts a range to be measured from the optical signal received by the detection unit. The spectrum extraction unit extracts an optical signal formed as a gas molecule of a gas to be measured absorbs energy of the optical signal. A determination unit determines the presence of an anomaly in the space to be measured based on a waveform of the optical signal extracted by the spectrum extraction unit.