A sensor apparatus includes: an element substrate; a detecting section disposed on an upper surface of the element substrate, the detecting section including a reaction section having an immobilization film to detect an analyte; a first IDT electrode configured to generate an acoustic wave which propagates toward the reaction section, and a second IDT electrode configured to receive the acoustic wave which has passed through the reaction section; and a protective film located on the upper surface of the element substrate so as to cover the first IDT electrode, the second IDT electrode, and at least part of the immobilization film, the protective film extending between and contacting with the immobilization film and at least one of the first IDT electrode and the second IDT electrode.

A fluidic device incorporating at least one BAW resonator structure (e.g., a biosensing device) and a fluidic passage includes one or more features that provide filtration capability. Certain embodiments include at least one group of pillars extending into the fluidic passage which are arranged between an active region of the at least one BAW resonator structure and at least one fluidic port. Individual pillars are separated from one another by inter-pillar spaces that provide redundant fluid flow paths while preventing passage of obstruction media such as particulate matter, cells, and/or bubbles. Certain embodiments provide porous material arranged in fluid communication with at least one fluidic port and configured to filter contents of fluid supplied thereto. Porous material (e.g., porous membranes) may be provided in a cover structure of a fluidic device or within a filtration cartridge.

The invention provides a chemical detection system for detecting at least one target chemical species, including a self-sensed cantilevered probe array having a plurality of self-sensed cantilevered probes, at least one chemical-sensitive coating material applied to at least one cantilevered probe in the cantilevered probe array, and an interface circuit that is coupled to the cantilevered probe array. At least one cantilevered probe in the cantilevered probe array exhibits a shifted cantilevered probe response when the cantilevered probe array is exposed to the target chemical species and the interface circuit actuates the cantilevered probe. A handheld chemical detection system and a method of operation are also disclosed.

A quartz crystal microbalance (QCM) sensor is proposed. The QCM sensor comprises a piezoelectric substrate and at least two electrodes in contact with the substrate to induce shear deformations therein through the inverse piezoelectric effect. The substrate has a sensing surface, and, on that surface, a pattern of plasmonic nanoparticle accumulations protruding from the surface. Each accumulation of nanoparticles comprises a plurality of plasmonic nanoparticles arranged about a hump. Plasmonic hot spots are present between neighbouring accumulations of the pattern that are separated a distance that amounts to or to less than the average diameter of the accumulations of the pattern.

Apparatus for chemical detection includes a pair of interdigitated transducers (IDTs) formed on a piezoelectric substrate. The apparatus includes a layer of adsorptive material deposited on a surface of the piezoelectric substrate between the IDTs, where each IDT is conformed, and is dimensioned in relation to an operating frequency and an acoustic velocity of the piezoelectric substrate, so as to function as a single-phase uni-directional transducer (SPUDT) at the operating frequency. Additionally, the apparatus includes the pair of IDTs is spaced apart along a propagation axis and mutually aligned relative to said propagation axis so as to define an acoustic cavity that is resonant to surface acoustic waves (SAWs) at the operating frequency, where a distance between each IDT of the pair of IDTs ranges from 100 wavelength of the operating frequency to 400 wavelength of the operating frequency.

An odor measurement apparatus includes an odor sensor detecting an odor and an imaging device having a lens portion, in which an imaging direction of the imaging device and an introduction direction of air when the air is guided to a sensor surface of the odor sensor through an introduction port are substantially the same direction. The odor measurement apparatus detects odor substances contained in air using a sensor when an odor is measured, and measures attribute information of a measurement target or the like of the odor. An odor data management apparatus stores and manages odor data measured by the odor measurement apparatus.

To provide a biosensor including a suctioning mechanism while using a detection element such as a surface acoustic wave device, included are: a first cover member 1 including an element-accommodating recess 5 on an upper face thereof; a detection element 3 including an element substrate 10, and at least one detection unit 13 located on the upper face of the element substrate 10 to perform detection of an analyte; and a second cover member 2 joined to the first cover member 1 and covering the detection element 3, and including an inflow port 14 from which the analyte flows in and a groove 15 extending from the inflow port 14 to at least above the detection unit.

Disclosed is an integrated circuit comprising a substrate (10); and an optical CO.sub.2 sensor comprising: first and second light sensors (12, 12′) on said substrate, said second light sensor being spatially separated from the first light sensor; and a layer portion (14) including an organic compound comprising at least one amine or amidine functional group over the first light sensor; wherein said integrated circuit further comprises a signal processor (16) coupled to the first and second light sensor for determining a difference in the respective outputs of the first and second light sensor. An electronic device comprising such a sensor and a method of manufacturing such an IC are also disclosed.

A fluidic device includes a base structure including at least one bulk acoustic wave (BAW) resonator structure having a fluidic passage containing at least one functionalized active region overlaid with functionalization material suitable to bind an analyte. One or more of a wall structure, a cover structure, or a portion of the base structure defining the fluidic passage includes additional functionalization material to form at least one absorber configured to bind at least one analyte. The dynamic measurement range of a BAW resonator structure is increased when the at least one absorber is placed upstream of the at least one functionalized active region.

A piezoelectric resonator for use in a sensor arrangement for detecting or measuring an analyte in a medium, comprises a quartz crystal plate, having a first crystal surface and a second crystal surface. The first crystal surface is provided with a first electrode, which has a surface area of less than 15 mm.sup.2 and the second crystal surface is provided with a second electrode. The first electrode may have a rectangular surface shape. A flow cell for use in an apparatus for detecting or measuring an analyte in a medium, comprises walls that form a sensing chamber together with the resonator, and inlet and outlet openings for leading a fluid through the sensing chamber. A part of the resonator constitutes one of the walls of the sensing chamber and is arranged such that the first electrode is situated inside the sensing chamber.