G01N2291/0423

Analyte depletion for sensor equilibration
11813612 · 2023-11-14 ·

Methods include treating a portion of a sample composition to be tested for presence of an analyte by depleting or blocking the target analyte. The treated composition may be used to equilibrate an acoustic wave sensor prior to exposing the sensor to the untreated sample composition for analysis. By using the treated sample composition, in which the analyte is depleted or blocked, to equilibrate the sensor, the sensor may be equilibrated with a composition having a similar viscosity and non-specific binding characteristics to the untreated sample composition, which should result in improved accuracy when analyzing the analyte in the untreated sample composition.

Self-calibrating analyte sensor

A sensor device comprises at least one transducer and a sensing material disposed on the transducer. The sensing material adsorbs or absorbs an amount of analyte (e.g., a target gas) that depends on a temperature of the sensing material and a concentration of the analyte. At least one detector is arranged to measure responses of the transducer to sorption or desorption of the analyte in the sensing material while the sensing material is heated and/or cooled according to at least one temperature profile. The device also comprises a humidity sensor that is arranged to detect a humidity level of the environment or sample containing the analyte. A processor or controller is programmed to determine the quantity (e.g., concentration) of the analyte by comparing values of the transducer measurement signals to reference data indicative of expected or pre-measured responses of the transducer to known concentrations of the analyte at the same humidity level as indicated by the humidity sensor while the sensing material is subjected to the same or similar temperature profile.

Surface acoustic wave sensors for air data probes

An air data system includes an air data probe and a surface acoustic wave (SAW) sensor attached to the air data probe for detecting particulate accumulation. The air data probe includes a probe head, a strut connected to the head, and a mounting plate connected to the strut. The probe head has an inlet, an interior surface extending from the inlet, and an exterior surface extending from the inlet.

DIAGNOSTIC METHODS AND DEVICE

A method for evaluating Dry Eye Disease (“DED”) in a human or animal subject is provided. Thread thinning dynamics of a tear sample of the subject are determined using an acoustically-driven microfluidic extensional rheometry instrument. At least one physical parameter value of the tear sample is calculated based at least in part on the determined thread thinning dynamics. DED is evaluated based at least in part on the at least one calculated physical parameter value of the tear sample. A device for evaluating Dry Eye Disease (DED) in a human or animal subject is also provided. The device includes an acoustically-driven microfluidic extensional rheometry instrument and a processing device configured to evaluate DED based at least in part on the calculated at least one physical parameter value of the tear sample.

Method and system for controlling the integrated health of a mechanical structure by diffuse elastic waves

A method for monitoring the structural health of a structure that supports guided propagation modes of elastic waves, includes the following steps: a) acquiring an ambient noise propagating through the structure by means of at least one pair of non-collocated elastic-wave sensors; b) estimating a function representative of an impulse response of the structure for elastic propagation between the constituent sensors of said pair; c) extracting at least one dispersion curve of the elastic propagation through the structure by time-frequency analysis of this function representative of an impulse response; and d) estimating at least one parameter indicative of a mechanical property of a constituent material of the structure from the dispersion curve obtained in step c). A system for implementing such a method is also provided.

Sample liquid sensor device
11435318 · 2022-09-06 · ·

A specimen liquid sensor apparatus includes a specimen liquid sensor having an external terminal and a reader on which the specimen liquid sensor can be detachably attached. The reader includes a first portion, a second portion that can be displaced with respect to the first portion. A connection terminal located on an upper surface of the first portion, and an external terminal of the specimen liquid sensor and a connection terminal of the reader are in contact with each other in a closed state in which the specimen liquid sensor is located between an upper surface of the first portion and a lower surface of the second portion.

Method, apparatus, system and sensor for detecting multi-mode electromagnetic acoustic and magnetic flux leakage

The disclosure discloses a method, apparatus and system for detecting multi-mode electromagnetic acoustic and magnetic flux leakage and a sensor. The method comprises: S102, receiving an operation instruction for detecting an object to be detected, the operation instruction is used for controlling a detection sensor to enter into any one or more of working modes as follows: magnetic flux leakage detection, ultrasonic bulk wave detection, ultrasonic guided wave detection and surface wave detection; S104, controlling the detection sensor to output a corresponding detection signal according to the operation instruction; and S106, detecting the object to be detected on the basis of the detection signal. The technical solution achieves a purpose of using one sensor to realize various detection modes, such as magnetic flux leakage and electromagnetic acoustic modes, reduces complexity and cost of a detection system, and improves detection efficiency.

Surface wave detection of surface defects

A moving robot has at least one surface wave transducer or a transmitter and receiver, to identify defects on or in a surface on which the robot moves, and provide data indicative of the location, size and/or orientation of the defects from robot position data.

Fluid meter and fluid measuring module for a fluid measuring device and assembly

A fluid meter has a housing comprising a flow channel for fluid to be measured and at least one elongate module-receiving opening forming a passage from an outer surface of the housing to the flow channel. At least one fluid-measuring module, prefabricated separately, from the housing with a base section formed as a waveguide for surface acoustic waves, and at least one signal transformer to excite surface acoustic waves in the waveguide and/or receive surface acoustic waves from the waveguide is provided. When inserted into the module-receiving opening, the base section of the fluid-measuring module forms part of the flow channel inner wall and contacts fluid flowing through it. Surface acoustic waves emitted by the signal transformer can be coupled out of the waveguide and can propagate through fluid in the flow channel as bulk acoustic waves and/or bulk acoustic waves can be coupled into the waveguide and received by the signal transformer.

ANALYTE DEPLETION FOR SENSOR EQUILIBRATION
20220288582 · 2022-09-15 ·

Methods include treating a portion of a sample composition to be tested for presence of an analyte by depleting or blocking the target analyte. The treated composition may be used to equilibrate an acoustic wave sensor prior to exposing the sensor to the untreated sample composition for analysis. By using the treated sample composition, in which the analyte is depleted or blocked, to equilibrate the sensor, the sensor may be equilibrated with a composition having a similar viscosity and non-specific binding characteristics to the untreated sample composition, which should result in improved accuracy when analyzing the analyte in the untreated sample composition.