Utilization of a contact device placed on the eye in order to detect physical and chemical parameters of the body as well as the non-invasive delivery of compounds according to these physical and chemical parameters, with signals being transmitted continuously as electromagnetic waves, radio waves, infrared and the like. One of the parameters to be detected includes non-invasive blood analysis utilizing chemical changes and chemical products that are found in the conjunctiva and in the tear film. A transensor mounted in the contact device laying on the cornea or the surface of the eye is capable of evaluating and measuring physical and chemical parameters in the eye including non-invasive blood analysis. The system utilizes eye lid motion and/or closure of the eye lid to activate a microminiature radio frequency sensitive transensor mounted in the contact device. The signal can be communicated by wires or radio telemetered to an externally placed receiver. The signal can then be processed, analyzed and stored. Several parameters can be detected including a complete non-invasive analysis of blood components, measurement of systemic and ocular blood flow, measurement of heart rate and respiratory rate, tracking operations, detection of ovulation, detection of radiation and drug effects, diagnosis of ocular and systemic disorders and the like.

To acquire information relating to a vessel wall thickness by: acquiring interference signal sets of a plurality of frames including interference signal sets corresponding to a plurality of frames forming an image of the same cross section of an fundus; generating 3-D tomographic image data on the fundus from the interference signal sets of the plurality of frames; generating 3-D motion contrast data in the fundus from the interference signal sets corresponding to the plurality of frames that form the same cross section; extracting a vessel from the fundus based on the 3-D tomographic image data or the 3-D motion contrast data; detecting a coordinate of an outer surface of a vessel wall of the vessel based on the 3-D tomographic image data; and detecting a coordinate of an inner surface of the vessel wall of the vessel based on the 3-D motion contrast data.

The invention concerns a method for measuring parameters necessary for producing corrective spectacles using an instrument (1) comprising the following steps: S1: positioning the wearer at a predefined distance from the frame (2) of the instrument (1), S2: placing a screen (5) of the instrument (1) opposite the wearer and displaying at least one image, S3: placing the frame of the corrective spectacles on the face of the wearer, S4: substituting the screen (5) with a one-way mirror (4) of the instrument, S5: taking the measurements.

An ophthalmic apparatus which photographs an endothelial cell and measures a coat thickness of a cornea of an eye to be examined in a non-contact manner; comprising an image pickup unit (19) for photographing a corneal endothelium of the eye to be examined, a control unit (49) for detecting a cell wall of the endothelial cell from a corneal endothelial image photographed by the image pickup unit and for performing an image processing of hatching the cell wall with a boundary line, a display unit (54) for displaying an analytical image in which the cell wall hatched with the boundary line, and an operation unit (55), wherein the control unit changes the shading of the boundary line based on an input from the operation unit.

A method, a device, and a computer program for determining a refractive error of at least one eye of a user are disclosed, as well as a method for manufacturing a spectacle lens for the user. The method entails: displaying a periodic pattern on a screen, wherein a parameter of the periodic pattern includes at least one spatial frequency, wherein the parameter of the periodic pattern is varied; detecting a reaction of the user indicating that the user is able to perceive the periodic pattern; determining a point in time at which the user perceives the periodic pattern; and determining a value for the refractive error of the eye or eyes of the user from the periodic pattern at that point in time, wherein the value for the refractive error is determined from the at least one spatial frequency, determined at the point in time, of the periodic pattern.

The ophthalmological device of an embodiment includes an optical system for inspection, a display, a subject's eye position acquiring unit, and a control unit. The optical system for inspection includes a photographic optical system for photographing an eyeground of the subject's eye. The subject's eye position acquiring unit acquires a three-dimensional position of the subject's eye. The control unit acquires information on positional displacement of the optical system for inspection with respect to the subject's eye on the basis of the three-dimensional position to cause a screen of the display to display two alignment index images to be varied in position with respect to a reference position of alignment preset in the display in a pseudo manner, in accordance with the information on positional displacement.

An image processing method includes acquiring a first direction fundus image imaged in a state in which an examined eye is directed in a first direction, and a second direction fundus image imaged in a state in which the examined eye is directed in a second direction different to the first direction, generating a combined image for analyzing a fundus-peripheral portion of the examined eye by combining the first direction fundus image and the second direction fundus image, and outputting the combined image.

End user interactions at a display are monitored for predetermined conditions to provide augmentation of display presentation by a red light that illuminates in the 650 to 800 nm range, such as at substantially 670 nm. Instructions stored in non-transient memory and executed on a processor present visual images of varied color contrast and evaluate end user inputs to determine an end user visual acuity. Over time and use of the display and red light, end user visual acuity is periodically tested to evaluate the effectiveness of red light illumination to restore visual acuity.

Methods and systems herein can include displaying at least one image to a test subject, wherein the at least one image has a visual appearance to the test subject based on physical characteristics of the eyes of the test subject, obtaining input from the test subject regarding the visual appearance of the at least one image, and calculating an optical parameter of the test subject based on the input from the test subject.

An ophthalmologic apparatus includes a data acquisition unit, a movement mechanism, an image acquisition unit, an analyzer, and a controller. The data acquisition unit includes an optical system for optically acquiring data of a fundus of a subject's eye. The movement mechanism is configured to change relative position between the subject's eye and the data acquisition unit. The image acquisition unit is configured to acquire an image of the fundus. The analyzer is configured to specify a relative movement direction and relative movement amount of the data acquisition unit with respect to the subject's eye based on a flare region formed all around a fundus region in the image. The controller is configured to control the movement mechanism based on the relative movement direction and the relative movement amount to change relative position between the subject's eye and the data acquisition unit in an optical axis direction of the optical system.